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Cat No. | Product Name | Synonyms | Targets |
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T9189 | Iptacopan hydrochloride | Iptacopan HCl,LNP023 hydrochloride | Complement System |
Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity b... | |||
T13041 | Surfactin | HSV | |
Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, with anti-bacterial, anti-fungal, antimycoplasma and hemolytic eff... | |||
TP1018L | Urechistachykinin II acetate | Urechistachykinin II acetate(149097-04-1 free base),Uru-TK II acetate | Others |
Urechistachykinin II acetate (Uru-TK II acetate) is an invertebrate rapid kinin-related peptide (TRPs) isolated from carotenoid worms, shows antimicrobial activities without a hemolytic effect | |||
T1386 | Phenazopyridine hydrochloride | Urodine,Pyridium,Phenazopyridine HCl | Sodium Channel |
Phenazopyridine hydrochloride (Pyridium) is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include nausea, interference with the oxygen-carrying capacity of red... | |||
T76867 | Ravulizumab | ALXN1210 | Complement System |
Ravulizumab (ALXN1210) is a humanized monoclonal antibody targeting complement factor 5 that specifically binds to human complement protein C5 with high affinity to block complement activation. Ravulizumab can be used fo... | |||
T8509 | Danicopan | ACH-4471 | Complement System |
Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the ... | |||
T25702 | Levovirin | ICN 17261,L-Ribavirin,ICN-17261,ICN17261 | |
Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin. Levovirin has similar immunomodulatory activity but does not have direct antiviral activity or h... | |||
T79468 | Antimicrobial agent-22 | ||
Antimicrobial agent-22 (THI 6c) constitutes a broad-spectrum, multi-target antibacterial with notable rapid bactericidal efficacy and effective anti-biofilm activity, paired with low cytotoxicity and hemolytic properties... | |||
T80394 | Des(8-14)brevinin-1PMa | ||
Des(8-14)brevinin-1PMa is a host-defense peptide known for its potent antimicrobial properties, particularly against Staphylococcus aureus and Echerichia coli. Additionally, this compound demonstrates hemolytic activity ... | |||
T81514 | Peptide 5f | ||
Peptide 5f, sourced from wasp venom, exhibits antimicrobial properties effective against both bacterial and fungal pathogens, while demonstrating minimal hemolytic activity on human red blood cells [1]. | |||
T16992 | Taribavirin hydrochloride | Others | |
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin hydrochloride is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distr... | |||
T80373 | Maximin 77 | ||
Maximin 77 is an antimicrobial peptide with antibacterial activity against S. aureus (MIC: 18.8 μg/mL) and exhibits hemolytic activities against human red cells [1]. | |||
T38259 | Phenelfamycin E | ||
Phenelfamycin E is an antibiotic originally isolated from Streptomyces. It is active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus128 μg/ml). Phenelfamycin E (4-64 mg/kg) inc... | |||
T80398 | Brevinin-1PMa | ||
Brevinin-1PMa is a host-defense peptide with antimicrobial properties effective against both Staphylococcus aureus and Escherichia coli, as well as demonstrated hemolytic activity [1]. | |||
T80370 | Maximin 42 | ||
Maximin 42 is an antimicrobial peptide with antibacterial activity against S. aureus (MIC: 37.5 μg/mL) and exhibits hemolytic activities against human red cells [1]. | |||
T75582 | Naja Melanoleuca Venom | ||
Naja Melanoleuca Venom (Forest Cobra Venom) is a snake venom derived from Naja Melanoleuca, exhibiting hemolytic activity against human erythrocytes. It contains α-neurotoxins that isolate from the venom and inhibit the ... | |||
T80366 | Maximin 49 | ||
Maximin 49, an antimicrobial peptide, exhibits antibacterial activity against S. aureus (MIC: 18.8 μg/mL) and demonstrates hemolytic activities on human and rabbit red cells [1]. | |||
T80363 | Maximin 41 | ||
Maximin 41, an antimicrobial peptide, exhibits antibacterial activity against S. aureus with a minimum inhibitory concentration (MIC) of 75 μg/mL and demonstrates hemolytic activities against human red cells [1]. | |||
T16993 | Taribavirin | Others | |
Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cel... | |||
T63552 | FtsZ-IN-1 | ||
FtsZ-IN-1 is a potent FtsZ inhibitor with a quinoline ring and has a strong inhibitory effect on Gram-positive bacteria (MIC: 0.5-8 μg/mL).FtsZ-IN-1 enhances FtsZ polymerization and significantly promotes cell elongation... | |||
T80368 | Im5 | ||
Im5, an antimicrobial peptide, exhibits antibacterial activity, with minimum inhibitory concentrations (MIC) of 10 μM for E. coli, 2.5-5 μM for S. aureus, and 0.5-1 μM for B. subtilis, as well as hemolytic activity with ... | |||
T74527 | Anti-MRSA agent 4 | ||
Anti-MRSA agent 4 (compound 7a), a selective and potent inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA) growth, demonstrates a minimum inhibitory concentration (MIC) of ≤ 0.26 µM. It exhibit... | |||
T76570 | PSM-β | ||
PSM-β, an active peptide isolated from Staphylococcus epidermidis, acts as an analog of staphylococcal toxins and is also known as a phenol-soluble modulin (PSM). PSM-β exhibits bacteriostatic properties and possesses mi... | |||
T80365 | Maximin H39 | ||
Maximin H39, an antimicrobial peptide, exhibits antibacterial activity against C. albicans, S. aureus, and B. subtilis with minimum inhibitory concentrations (MIC) of 9.4, 9.4, and 18.8 μg/mL, respectively. It also demon... | |||
T80369 | Maximin 68 | ||
Maximin 68, an antimicrobial peptide, exhibits antibacterial activity against C. albicans, S. aureus, E. coli, and B. subtilis, with MIC values of 18.8, 9.4, 37.5, and 9.4 μg/mL, respectively. It also possesses hemolytic... | |||
T80139 | CRAMP-18 (mouse) | Antibiotic | |
CRAMP-18 (mouse) is an antibiotic peptide with demonstrated efficacy against Gram-negative bacteria, including S. typhimurium and P. aeruginosa, while exhibiting no hemolytic activity. This compound shows promise for res... | |||
T80364 | Maximin 45 | ||
Maximin 45, an antimicrobial peptide, exhibits antibacterial activity against S. aureus, E. coli, and B. subtilis with minimum inhibitory concentrations (MIC) of 4.7, 9.4, and 75 μg/mL, respectively. Additionally, it pos... | |||
T71266 | Omadacycline HCl | ||
Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant S... | |||
T78914 | S-F24 | ||
S-F24 is a broad-spectrum antifungal agent that demonstrates potent inhibition of CYP3A4, with an IC50 of 0.4 μM. It exhibits a favorable safety profile, characterized by high selectivity, minimal hemolytic effects, and ... | |||
T73127 | C16-K-cBB1 | ||
C16-K-cBB1 is a potent, selective antimicrobial agent effective against Methicillin-resistant Staphylococcus aureus (MRSA), demonstrated by its minimal inhibitory concentration (MIC) of 1 µg/mL. This compound exhibits ex... | |||
T74553 | YSK 05 | ||
YSK 05, a pH-sensitive cationic lipid, enhances the intracellular trafficking of non-viral vectors, significantly improves gene silencing and hemolytic activities in its modified form YSK 05-MEND, and effectively overcom... | |||
T76468 | Cecropin A (1-7)-Melittin A (2-9) | ||
Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide that exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative aerobic bacteria, in addition to antimalarial properties. Not... | |||
T80367 | Maximin 78 | ||
Maximin 78 is an antimicrobial peptide with antibacterial activity against C. albicans, S. aureus, and B. subtilis, exhibiting minimum inhibitory concentrations (MIC) of 37.5, 4.7, and 37.5 μg/mL, respectively. Additiona... | |||
T78935 | Quorum Sensing-IN-2 | ||
Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor that curtails bacterial pathogenicity without impeding growth. It demonstrates minimal hemolytic activity while effectively inhibiting bacterial infections... | |||
T74788 | FtsZ-IN-5 | ||
FtsZ-IN-5 is a potent inhibitor of FtsZ, promoting polymerization while inhibiting its GTPase activity, thereby preventing bacterial division and leading to cell death. It exhibits bactericidal activity without significa... | |||
T74790 | FtsZ-IN-7 | ||
FtsZ-IN-7 is a potent inhibitor of FtsZ, enhancing FtsZ polymerization while inhibiting its GTPase activity, therefore disrupting bacterial cell division and culminating in bacterial cell death. It exhibits bactericidal ... | |||
T80378 | Tilapia piscidin 3 | ||
Tilapia piscidin 3, an antimicrobial peptide, exhibits antibacterial properties effective against both gram-positive and gram-negative bacteria. It has demonstrated minimum inhibitory concentrations (MICs) of 2.44 µg/mL ... | |||
T80252 | BMAP-18 | ||
BMAP-18 is a biologically active peptide, a truncated derivative of BMAP-27, which is part of the Cathelicidin family of peptides known for their potent bactericidal properties against pathogens such as Staphylococcus au... | |||
T80262 | SMAP-18 | ||
SMAP-18, an 18-amino acid residue peptide amide, is a biologically active truncated variant of Sheep myeloid antimicrobial peptide-29 (SMAP-29). It retains potent antimicrobial activity against Pseudomonas strains, other... | |||
T74789 | FtsZ-IN-6 | ||
FtsZ-IN-6 is a potent inhibitor of FtsZ, enhancing its polymerization while inhibiting its GTPase activity, thereby obstructing bacterial cell division and causing bacterial cell death. This compound exhibits bactericida... | |||
T74791 | FtsZ-IN-8 | ||
FtsZ-IN-8, a potent inhibitor of FtsZ, both promotes FtsZ polymerization and inhibits its GTPase activity, leading to the inhibition of bacterial division and subsequent bacterial cell death. This compound exhibits bacte... | |||
T82474 | Empasiprubart | ARGX-117 | |
Empasiprubart (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. It inhibits the formation of C3 proconvertase, obstructing classical and lectin pathway activation by binding to the Sushi-2... | |||
T80286 | TP4 (Nile tilapia piscidin) | Necroptosis | |
TP4 (Nile tilapia piscidin) is an orally active piscidin-like antimicrobial peptide that exhibits inhibition of various gram-positive and negative bacterial strains with a minimum inhibitory concentration (MIC) ranging f... | |||
T37873 | CAP 3 | ||
CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 μM, respectively). CAP 3 increas... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN6864 | Prosaikogenin F | (2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol | Others |
Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3... | |||
TN2088 | Platycodin D2 | IL Receptor , HBV | |
Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses. Polygalaci... | |||
T3368 | Alpha-Hederin | Helixin,Tauroside E,α-Hederin,Hederoside C | Apoptosis , Others |
Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties. | |||
T3891 | Oroxylin A-7-O-glucuronide | Oroxylin A Glucoronide,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide | Others |
Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM)... | |||
T41138 | Prosaikogenin H | ||
Prosaikogenin H, an intestinal metabolite derived from saikosaponin, exhibits weak hemolytic activity. | |||
TN4804 | Platycoside A | Antifection | |
Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG1 antibody responses in the immunized mi... | |||
TN5930 | Ocotillone | ||
Ocotillone has potent antibacterial activity against Gram-negative bacteria, P. aeruginosa and S. typhimurium, that are without hemolytic activity, whereas it has weak antimicrobial activity against Gram-positive bacteri... | |||
T76129 | Hemocyanin | ||
Hemocyanin, a substantial copper-bearing respiratory protein, serves as a crucial molecule in non-specific innate immune defense, exhibiting phenoloxidase, antiviral, antibacterial, hemolytic, and antitumor activities [1... | |||
T36439 | Gramicidin A | Antibacterial , HIF , Parasite | |
Gramicidin A is a peptide antibiotic isolated from B. brevis.Gramicidin A is a highly hydrophobic channel-forming ion carrier that forms monovalent cation-permeable channels in artificial membranes.Gramicidin A induces t... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01075 | Von Willebrand Factor/vWF Protein, Human, Recombinant (His) | Human | CHO |
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vasc... | |||
TMPH-00512 | Lysenin-related protein 2 Protein, Eisenia foetida, Recombinant (His & Myc) | Eisenia fetida | E. coli |
Pore-forming toxin that specifically binds sphingomyelin in the plasma membrane of various cells. Has hemolytic activity. It also has antibacterial activities against B.megaterium. | |||
TMPH-00636 | Hemolysin E, chromosomal Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells. | |||
TMPH-03554 | HlgB Protein, S. aureus, Recombinant (E. coli, His) | Staphylococcus aureus | E. coli |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. | |||
TMPH-03555 | HlgB Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | Yeast |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. | |||
TMPH-03557 | HlgC Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | Yeast |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. | |||
TMPH-03553 | HlgA Protein, S. aureus, Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. | |||
TMPH-03556 | HlgC Protein, S. aureus, Recombinant (E. coli, His) | Staphylococcus aureus | E. coli |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. | |||
TMPY-04765 | PKLR Protein, Human, Recombinant (His) | Human | E. coli |
Pyruvate kinase (PKLR) is a critical erythrocyte enzyme that is required for glycolysis and production of ATP. Pyruvate kinase deficiency (PKD) is the most frequent red blood cell enzyme abnormality of the glycolytic pat... | |||
TMPJ-01306 | CFHR5 Protein, Human, Recombinant (His) | Human | Human Cells |
Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other... | |||
TMPH-00037 | Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His) | Aggregatibacter actinomycetemcomitans | Yeast |
Virulence factor that plays an important role in immune evasion. Lyses human lymphocytes and monocytes. Binds to the LFA-1 integrin on the surface of the host cell and to cholesterol-containing membranes, which probably ... | |||
TMPJ-01034 | TIM Protein, Human, Recombinant (His) | Human | E. coli |
Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3... | |||
TMPH-03035 | M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His) | Myrmecia pilosula | Baculovirus |
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum ... | |||
TMPH-02174 | PYCR1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
TMPH-02414 | Lys-gingipain W83 Protein, Porphyromonas gingivalis, Recombinant (His) | Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the fun... | |||
TMPH-00387 | Toxin CfTX-1 Protein, Chironex fleckeri, Recombinant (His & SUMO) | Chironex fleckeri | E. coli |
May cause profound effects on the cardiovascular system of anesthetized rats (at 25 ug/kg), since the fraction containing this toxin and CfTX-2 produces an initial increase in mean arterial pressure, followed by cardiova... | |||
TMPJ-00800 | BPGM Protein, Human, Recombinant (His) | Human | E. coli |
Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,... | |||
TMPH-00511 | Lysenin Protein, Eisenia fetida, Recombinant (His) | Eisenia fetida | E. coli |
Pore-forming toxin that defensively acts against parasitic microorganisms by forming pores in sphingomyelin-containing membranes. Has hemolytic activity and is also cytotoxic to spermatozoa of some species of invertebrat... | |||
TMPY-02023 | CD46 Protein, Human, Recombinant (His) | Human | HEK293 |
CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white bloo... | |||
TMPY-03271 | Thrombomodulin Protein, Rat, Recombinant (His) | Rat | HEK293 |
Thrombomodulin, also known as THBD (CD141), is an integral membrane protein that reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the ... | |||
TMPJ-00836 | G6PD Protein, Human, Recombinant (His) | Human | Human Cells |
Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by ... | |||
TMPJ-00979 | GSH-S Protein, Human, Recombinant (His) | Human | E. coli |
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glyci... | |||
TMPY-05829 | Thrombomodulin Protein, Human, Recombinant (His) | Human | HEK293 |
Thrombomodulin, also known as THBD (CD141), is an integral membrane protein that reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the ... | |||
TMPY-02835 | DEFB103A Protein, Human, Recombinant (His) | Human | E. coli |
Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. B... | |||
TMPY-04129 | Complement factor H/CFH Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Complement factor H, also known as H factor 1, and CFH, is a sialic acid containing glycoprotein that plays an integral role in the regulation of the complement-mediated immune system that is involved in microbial defens... | |||
TMPY-04141 | Complement factor H/CFH Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Complement factor H, also known as H factor 1, and CFH, is a sialic acid containing glycoprotein that plays an integral role in the regulation of the complement-mediated immune system that is involved in microbial defens... |