factor

3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) is a bile acid metabolite that inhibits TH17 cell differentiation by directly binding to the transcription factor RORγt with a Kd of 1.13 μM.

α-Factor Mating Pheromone, yeast acetate (Mating Factor α acetate) is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.

Euphorbia factor L25 is a useful organic compound for research related to life sciences and the catalog number is T125089.

Euphorbia factor L7a is a diterpene found in the seeds of Morinda citrifolia.

Euphorbia factor L9 is a useful organic compound for research related to life sciences and the catalog number is T126086.

Euphorbia factor L22 is a useful organic compound for research related to life sciences and the catalog number is T125686.

Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.

Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, anti-osteoclastogenic, and multidrug-resistant regulatory effects.

Deoxy euphorbia factor L1 is a natural product found in the seeds of Euphorbia lathyris L

Euphorbia factor L7b,a natural product obtained from the herbs of Euphorbia pekinensis Rupr.

α-Factor Mating Pheromone (yeast TFA) is a tridecapeptide secreted by Saccharomyces cerevisiae α cells and interacts with the Ste2p receptor [1].

Epidermal Growth Factor, murine submaxillary gland, is a bioactive polypeptide isolated from the submaxillary gland of mice. This growth factor acts as a mitogen, promoting the proliferation of epithelial cells, fibroblasts, and glial cells under a variety of experimental conditions.

Euphorbia factor L24 is a useful organic compound for research related to life sciences and the catalog number is T125685.

Euphorbia factor L8 is a diterpene from Morinda citrifolia seeds.

Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation.

Nimbolide suppresses CDK4 CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene derived from the leaves and flowers

5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.

Phorbol 12-myristate 13-acetate (PMA), a member of the phorbol ester group of natural products, activates PKC, SphK, and NF-κB, and induces THP1 cell differentiation.

5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.

Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathway.

1-PeCSO is isolated from onion or garlic bulbs. It acts as a key compound in garlic greening and reacts with lachrymatory factor synthase.

DMAPT (Dimethylamino Parthenolide) is an orally active NF-κB inhibitor and a Parthenolide (PTL) analogue with an LD50 value of 1.7 μM for primary acute myeloid leukemia cells. It has potential anti-tumor and anti-metastatic effects.

Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.

Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.