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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
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TargetMol
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Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Search Result

Search Results for " embryonic "

Targets

Others

76

Compounds

4

Natural Products

377

Recombinant Proteins

4

Libraries

Cat No. Product Name Synonyms Targets
T27246 EG1 Others
EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.
T16695 Pyrintegrin Integrin
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...
T11996 MELK-8a hydrochloride MELK
MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 2 nM). 
T38155 N-Acetyl-D-cysteine Reactive Oxygen Species
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.
T8987 Epiblastin A Casein Kinase
Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).
T2161 Cardiogenol C Wnt/beta-catenin
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
T24706 RBC10 RBC 10,RBC-10 GTPase
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines.
T9681 MAK-683 hydrochloride Histone Methyltransferase
MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED). MAK683 exhibits IC50s of 59, 26, 89 nM in EED Alphascreen binding, ELISA and LC-MS assay.
T21981 Phthalazinone pyrazole Aurora Kinase
Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.
T6848 GSK1016790A GSK101 Calcium Channel , TRP/TRPV Channel
GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells.
T1874 PPQ-102 PPQ102,CFTR Inhibitor,PPQ 102 CFTR , Autophagy
PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).
T2431 ID-8 ID8 DYRK
ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.
T1759 OTSSP167 MELK inhibitor,OTS167 MELK
OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.
T21559 OTSSP167 hydrochloride MELK
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).
T11997 MELK-IN-1 Nintedanib Impurity L,MELK inhibitor 17 MELK
MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).
T8005 Cardiogenol C hydrochloride Cardiogenol C HCl,Cardiogenol C Wnt/beta-catenin
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
T11571 HLY78 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine Wnt/beta-catenin
HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.
T3221 Oct3/4-inducer-1 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile Others , OCT
Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.
T7196 HG-10-102-01 LRRK2
HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).
TP1286 Carcinoembryonic Antigen CEA Others
Carcinoembryonic antigen (CEA) is a protein that is present in certain tissues of a developing baby (fetus)
T3162 IDE1 Others
IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM...
T15201 MAK683 Histone Methyltransferase
MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).
T24152 HTH-01-091 HTH-01091,HTH01-091,HTH 01-091,HTH 01091 Serine/threonin kinase , Pim , MELK , DYRK , CDK , RIP kinase
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK and CLK2. HTH-01-091 can be used to study breast cancer.
T6948 Pluripotin SC1 ERK , Raf , S6 Kinase
Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP.
T11469 GSK-3484862 DNA Methyltransferase
GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer.
T3458 EED226 Histone Methyltransferase
EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.
T22322 EEDi-5285 UM-EEDi-5285,EEDI5285 Histone Methyltransferase
EEDi-5285, an orally active and highly potent inhibitor targeting embryonic ectoderm development (EED) protein, exhibits anti-cancer activity. It demonstrates exceptional efficacy with an IC50 value of 0.2 nM, indicating...
T78170 Kras4B G12D-IN-1 Ras
Kras4B G12D-IN-1 is an anticancer agent that functions as an inhibitor of the Kras4B G12D protein. It effectively reduces the expression of Kras protein in mouse embryonic fibroblasts (MEFs) harboring the Kras4B G12D mut...
T2019 OAC2 OCT
OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibrobl...
T2301 SB 202190 FHPI,SB202190 Apoptosis , p38 MAPK , Autophagy
SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably. SB 202190 has antitumor activity and also induces the differentiation of human embryonic stem cells i...
T35834L (Sar¹)-Angiotensin II acetate RAAS
(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. It can stimulate protein synthesis and cell...
T60143 MitoBloCK-6 Apoptosis
MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC 50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 with IC 50 of 1.4 μM. MitoBloCK-6 can induce apoptosis via cytochrome c release in human embryo...
T2310 CHIR-99021 Laduviglusib,CT99021,CHIR-99021 GSK-3 , Wnt/beta-catenin , Autophagy
CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in...
TP1345 Kisspeptin-10, human (TFA)(374675-21-5,FREE) GPR , Kisspeptin
Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role i...
T3637 Pifithrin-β hydrobromide Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide) Ferroptosis , p53
Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorder...
T28866 Stemazole Apoptosis
Stemazole is a novel small molecule human stem/progenitor cell proliferation activator that promotes the survival of human embryonic stem cells and maintains stemness, and promotes the survival of oligodendrocyte precurs...
T36935 PKUMDL-LC-101-D04 GPX4-Activator-1d4,PKUMDL-LC-101-D04 GPX
PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 μM in a cell-free...
T77697 BML-278 BML278,BML 278 Sirtuin , Histone Methyltransferase
BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and can be used to improve early embryonic development.BML-278 ind...
T2310L CHIR-99021 HCl CT99021 HCl,Laduviglusib HCl GSK-3
CHIR-99021 HCl (Laduviglusib HCl) is a highly potent and selective inhibitor of GSK-3α/β, with IC50 values of 10 nM and 6.7 nM respectively. It demonstrates remarkable selectivity for GSK-3, with over 500-fold selectivit...
T70578 BX-795 hydrochloride
BX-795 hydrochloride is a TBK1 and IKKε inhibitor. BX-795 is a potential maternal embryonic leucine zipper kinase inhibitor.
T24129 HBX28258 HBX 28258,HBX-28258
HBX28258 is a recombinant human USP7 protein inhibitor. In human colon cancer and embryonic kidney cell, it acts by binding the active site through a covalent mechanism and selectively inactivating USP7 protein.
T70520 TWS-119
TWS-119 is an inhibitor of glycogen synthase kinase-3β (GSK-3β) that induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs).
T35549 Elsinochrome A
Elsinochrome A is a perylenequinone fungal metabolite that has been found inHypomycesand has anticancer activity.1Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus ...
T40154 FTX-6058
FTX-6058 is a potent orally active inhibitor targeting Embryonic Ectoderm Development (EED). It effectively induces HbF protein expression in both cell and murine models. This compound holds significant potential for res...
T73867 HTH-01-091 TFA
HTH-01-091 TFA, a potent and selective inhibitor of maternal embryonic leucine zipper kinase (MELK), exhibits an IC50 of 10.5 nM. Besides its primary target, it also inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK, and CLK2, pos...
T40155 FTX-6058 hydrochloride
FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED), with the ability to induce HbF protein expression in both cell and murine models. This compound is particularly valu...
T35561 MS351
MS351 is an antagonist of chromobox 7 (CBX7) that acts by binding the CBX7 chromodomain. It enhances the binding of long noncoding RNA to the CBX7 chromodomain when used at 25 μM. MS351 induces transcriptional derepressi...
T69743 MEDS433
MEDS433 is a dihydroorotate dehydrogenase inhibitor (IC50 1.2 nM). MEDS433 inhibited the in vitro replication of hCoV-OC43 and hCoV-229E, as well as of SARS-CoV-2, at low nanomolar range. Notably, the anti-SARS-CoV-2 act...
T73945 MAK683-CH2CH2COOH hydrochloride
MAK683-CH2CH2COOH, targeting embryonic ectoderm development protein (EED), alongside a VHL ligand for E3 ubiquitin ligase, contributes to the formulation of PROTAC EED degrader-1 and PROTAC EED degrader-2 [1].
T69429 Y27632 HCl hydrate
Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepa...

Compounds

EG1
T27246
Synonym:
Target: Others
Pyrintegrin
T16695
Synonym:
Target: Integrin
MELK-8a hydrochloride
T11996
Synonym:
Target: MELK
N-Acetyl-D-cysteine
T38155
Synonym:
Target: Reactive Oxygen Species
Epiblastin A
T8987
Synonym:
Target: Casein Kinase
Cardiogenol C
T2161
Synonym:
Target: Wnt/beta-catenin
RBC10
T24706
Synonym: RBC 10,RBC-10
Target: GTPase
MAK-683 hydrochloride
T9681
Synonym:
Target: Histone Methyltransferase
Phthalazinone pyrazole
T21981
Synonym:
Target: Aurora Kinase
GSK1016790A
T6848
Synonym: GSK101
Target: Calcium Channel, TRP/TRPV Channel
PPQ-102
T1874
Synonym: PPQ102,CFTR Inhibitor,PPQ 102
Target: CFTR, Autophagy
ID-8
T2431
Synonym: ID8
Target: DYRK
OTSSP167
T1759
Synonym: MELK inhibitor,OTS167
Target: MELK
OTSSP167 hydrochloride
T21559
Synonym:
Target: MELK
MELK-IN-1
T11997
Synonym: Nintedanib Impurity L,MELK inhibitor 17
Target: MELK
Cardiogenol C hydrochloride
T8005
Synonym: Cardiogenol C HCl,Cardiogenol C
Target: Wnt/beta-catenin
HLY78
T11571
Synonym: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine
Target: Wnt/beta-catenin
Oct3/4-inducer-1
T3221
Synonym: 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile
Target: Others, OCT
HG-10-102-01
T7196
Synonym:
Target: LRRK2
Carcinoembryonic Antigen CEA
TP1286
Synonym:
Target: Others
IDE1
T3162
Synonym:
Target: Others
MAK683
T15201
Synonym:
Target: Histone Methyltransferase
HTH-01-091
T24152
Synonym: HTH-01091,HTH01-091,HTH 01-091,HTH 01091
Target: Serine/threonin kinase, Pim, MELK, DYRK, CDK, RIP kinase
Pluripotin
T6948
Synonym: SC1
Target: ERK, Raf, S6 Kinase
GSK-3484862
T11469
Synonym:
Target: DNA Methyltransferase
EED226
T3458
Synonym:
Target: Histone Methyltransferase
EEDi-5285
T22322
Synonym: UM-EEDi-5285,EEDI5285
Target: Histone Methyltransferase
Kras4B G12D-IN-1
T78170
Synonym:
Target: Ras
OAC2
T2019
Synonym:
Target: OCT
SB 202190
T2301
Synonym: FHPI,SB202190
Target: Apoptosis, p38 MAPK, Autophagy
(Sar¹)-Angiotensin II acetate
T35834L
Synonym:
Target: RAAS
MitoBloCK-6
T60143
Synonym:
Target: Apoptosis
CHIR-99021
T2310
Synonym: Laduviglusib,CT99021,CHIR-99021
Target: GSK-3, Wnt/beta-catenin, Autophagy
Kisspeptin-10, human (TFA)(374675-21-5,FREE)
TP1345
Synonym:
Target: GPR, Kisspeptin
Pifithrin-β hydrobromide
T3637
Synonym: Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide)
Target: Ferroptosis, p53
Stemazole
T28866
Synonym:
Target: Apoptosis
PKUMDL-LC-101-D04
T36935
Synonym: GPX4-Activator-1d4,PKUMDL-LC-101-D04
Target: GPX
BML-278
T77697
Synonym: BML278,BML 278
Target: Sirtuin, Histone Methyltransferase
CHIR-99021 HCl
T2310L
Synonym: CT99021 HCl,Laduviglusib HCl
Target: GSK-3
BX-795 hydrochloride
T70578
Synonym:
Target:
HBX28258
T24129
Synonym: HBX 28258,HBX-28258
Target:
TWS-119
T70520
Synonym:
Target:
Elsinochrome A
T35549
Synonym:
Target:
FTX-6058
T40154
Synonym:
Target:
HTH-01-091 TFA
T73867
Synonym:
Target:
FTX-6058 hydrochloride
T40155
Synonym:
Target:
MS351
T35561
Synonym:
Target:
MEDS433
T69743
Synonym:
Target:
MAK683-CH2CH2COOH hydrochloride
T73945
Synonym:
Target:
Y27632 HCl hydrate
T69429
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T19720 Colcemid C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine Microtubule Associated
Colcemid (NSC-3096) is an inhibitor of microtubule polymerization. It used to study embryonic cloning.
T4S1102 Liensinine diperchlorate Liensinine-Perchlorate Mitophagy , Others , Autophagy
Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus. It inhibits late autophagy by blocking autophagosome-lysosome fusion and exhibits biological activities such as...
T75661 Thymopentin acetate
Thymopentin acetate, primarily secreted by the epithelial cells of the thymic cortex and medulla, serves as an effective immunomodulatory agent. It possesses a short plasma half-life of 30 seconds and significantly enhan...
T36954 Nemorosone
Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma ce...

Natural Products

Colcemid
T19720
Synonym: C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine
Target: Microtubule Associated
Liensinine diperchlorate
T4S1102
Synonym: Liensinine-Perchlorate
Target: Mitophagy, Others, Autophagy
Thymopentin acetate
T75661
Synonym:
Target:
Nemorosone
T36954
Synonym:
Target:

Recombinant Proteins

Species：
Human (211)
Mouse (96)
Rat (22)
Cynomolgus (12)
Rhesus (9)
Canine (6)
Cynomolgus,Rhesus (6)
Bovine (2)
Human,Rhesus (2)
Apis mellifera (1)
Expression System：
HEK293 (220)
E. coli (93)
Human Cells (37)
Baculovirus-Insect Cells (20)
Yeast (3)
CHO (2)
Baculovirus (1)
Tag：
His (119)
hFc (62)
Tag Free (32)
C-6His (18)
None (17)
N-terminal 6xHis-tagged (16)
C-His (14)
His,GST (12)
C-Fc (11)
C-His-Avi (10)
Cat No. Product Name Species Expression System
TMPY-02379 EED Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
EED is essential for regulating the repressive histone modification, histone 3 lysine 27 tri-methylation (H3K27me3) at many developmental genes. EED depletion significantly impeded erythroid maturation. EED depletion imp...
TMPY-04126 MUSTN1 Protein, Human, Recombinant (His) Human E. coli
MUSTN1 (Musculoskeletal, Embryonic Nuclear Protein 1) is a Protein Coding gene. It may play an important role in regulating musculoskeletal development in mammals. It belongs to the MUSTANG family. The MUSTN1 protein is ...
TMPY-03104 FGF-17 Protein, Human, Recombinant Human E. coli
FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including ...
TMPY-01064 TIE2 Protein, Human, Recombinant (His) Human HEK293
TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play...
TMPY-00930 TIE2 Protein, Human, Recombinant (His & hFc) Human HEK293
TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play...
TMPJ-00090 FGF-9 Protein, Human, Recombinant Human E. coli
Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inc...
TMPY-00890 Noggin/NOG Protein, Human, Recombinant (hFc) Human HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-05202 Noggin/NOG Protein, Human, Recombinant Human HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-01061 FGF-10 Protein, Human, Recombinant Human E. coli
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-02594 Noggin/NOG Protein, Mouse, Recombinant (hFc) Mouse HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-00972 FGFR2 Protein, Human, Recombinant (His & hFc) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His) Human,Rhesus HEK293
ERBB4 is a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. ERBB4 is ...
TMPY-03382 FGF-6 Protein, Human, Recombinant Human E. coli
FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi...
TMPY-00423 FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00804 FGF-9 Protein, Human, Recombinant (hFc) Human HEK293
Fibroblast growth factor 9 (FGF9) also known as Glia-activating factor or Heparin-binding growth factor 9, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell sur...
TMPY-03357 FGFR2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant Human Human Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPY-00210 FGF-2 Protein, Mouse, Recombinant (His) Mouse E. coli
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in...
TMPJ-00842 FGF-2 Protein, Rat, Recombinant Rat E. coli
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. ...
TMPY-00749 FGF-2 Protein, Human, Recombinant Human E. coli
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in...
TMPY-06842 BMP-4 Protein, Human, Recombinant (E399D) Human E. coli
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPJ-00562 PDGF-BB Protein, Mouse, Recombinant (His) Mouse E. coli
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPY-04811 DKK1 Protein, Mouse, Recombinant (His) Mouse HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-00756 FGF-1 Protein, Human, Recombinant Human E. coli
aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which re...
TMPY-00775 DKK1 Protein, Human, Recombinant (His) Human HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPJ-01471 Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant Human/Mouse/Rat Human Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purifi...
TMPY-01174 DKK1 Protein, Rhesus, Recombinant (N256Q, His) Rhesus HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-00548 HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-01296 HGFR/c-Met Protein, Human, Recombinant (His) Human HEK293
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-00130 VISTA Protein, Mouse, Recombinant (hFc) Mouse HEK293
VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by in...
TMPY-01896 HGFR/c-Met Protein, Mouse, Recombinant (His) Mouse HEK293
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-03219 VISTA Protein, Human, Recombinant (His) Human HEK293
VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by in...
TMPJ-00147 FOLR1 Protein, Human, Recombinant (hFc) Human Human Cells
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lung and cerebellum. The secreted form is derived from the me...
TMPY-02626 FGF-18 Protein, Human, Recombinant (His) Human HEK293
Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-05004 FGF-4 Protein, Human, Recombinant Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPY-06935 FGF-21 Protein, Human, Recombinant Human E. coli
Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes ...
TMPY-01630 Syndecan-1 Protein, Human, Recombinant (His) Human HEK293
Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development...
TMPJ-00037 FGF-2 Protein, Mouse, Recombinant Mouse E. coli
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo...
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-04104 LIF Protein, Human, Recombinant Human HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-04278 LIF Protein, Mouse, Recombinant Mouse HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-02509 Alpha-fetoprotein Protein, Human, Recombinant (His) Human HEK293
Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitamin D (Gc) protein, and alpha-albumin. AFP is a glycoprotein of 591 amino acids and a carbohydrate moie...
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His) Human HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-00663 Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) Human HEK293
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal...
TMPY-03532 LIF Protein, Human, Recombinant (His) Human HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-01413 Cripto Protein, Human, Recombinant (His) Human HEK293
Cripto/TDGF1 is a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hy...
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His) Mouse Human Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept...
TMPY-01076 Gp130/IL6ST Protein, Human, Recombinant (His & hFc) Human HEK293
Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines...
TMPY-01832 Gp130/IL6ST Protein, Mouse, Recombinant (His) Mouse HEK293
Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines...
TMPY-03577 Pleiotrophin/PTN Protein, Mouse, Recombinant Mouse Baculovirus-Insect Cells
HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, ...
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EED Protein, Human, Recombinant (His & GST)
TMPY-02379
Species: Human
Expression System: Baculovirus-Insect Cells
MUSTN1 Protein, Human, Recombinant (His)
TMPY-04126
Species: Human
Expression System: E. coli
FGF-17 Protein, Human, Recombinant
TMPY-03104
Species: Human
Expression System: E. coli
TIE2 Protein, Human, Recombinant (His)
TMPY-01064
Species: Human
Expression System: HEK293
TIE2 Protein, Human, Recombinant (His & hFc)
TMPY-00930
Species: Human
Expression System: HEK293
FGF-9 Protein, Human, Recombinant
TMPJ-00090
Species: Human
Expression System: E. coli
Noggin/NOG Protein, Human, Recombinant (hFc)
TMPY-00890
Species: Human
Expression System: HEK293
Noggin/NOG Protein, Human, Recombinant
TMPY-05202
Species: Human
Expression System: HEK293
FGF-10 Protein, Human, Recombinant
TMPY-01061
Species: Human
Expression System: E. coli
Noggin/NOG Protein, Mouse, Recombinant (hFc)
TMPY-02594
Species: Mouse
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (His & hFc)
TMPY-00972
Species: Human
Expression System: HEK293
ErbB4 Protein, Human, Rhesus, Recombinant (His)
TMPY-02813
Species: Human,Rhesus
Expression System: HEK293
FGF-6 Protein, Human, Recombinant
TMPY-03382
Species: Human
Expression System: E. coli
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
TMPY-00423
Species: Human
Expression System: HEK293
FGF-9 Protein, Human, Recombinant (hFc)
TMPY-00804
Species: Human
Expression System: HEK293
FGFR2 Protein, Mouse, Recombinant (hFc)
TMPY-03357
Species: Mouse
Expression System: HEK293
TGF beta 2 Protein, Human, Recombinant
TMPJ-00258
Species: Human
Expression System: Human Cells
FGF-2 Protein, Mouse, Recombinant (His)
TMPY-00210
Species: Mouse
Expression System: E. coli
FGF-2 Protein, Rat, Recombinant
TMPJ-00842
Species: Rat
Expression System: E. coli
FGF-2 Protein, Human, Recombinant
TMPY-00749
Species: Human
Expression System: E. coli
BMP-4 Protein, Human, Recombinant (E399D)
TMPY-06842
Species: Human
Expression System: E. coli
PDGF-BB Protein, Mouse, Recombinant (His)
TMPJ-00562
Species: Mouse
Expression System: E. coli
DKK1 Protein, Mouse, Recombinant (His)
TMPY-04811
Species: Mouse
Expression System: HEK293
FGF-1 Protein, Human, Recombinant
TMPY-00756
Species: Human
Expression System: E. coli
DKK1 Protein, Human, Recombinant (His)
TMPY-00775
Species: Human
Expression System: HEK293
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
TMPJ-01471
Species: Human/Mouse/Rat
Expression System: Human Cells
DKK1 Protein, Rhesus, Recombinant (N256Q, His)
TMPY-01174
Species: Rhesus
Expression System: HEK293
HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-00548
Species: Cynomolgus,Rhesus
Expression System: HEK293
HGFR/c-Met Protein, Human, Recombinant (His)
TMPY-01296
Species: Human
Expression System: HEK293
VISTA Protein, Mouse, Recombinant (hFc)
TMPY-00130
Species: Mouse
Expression System: HEK293
HGFR/c-Met Protein, Mouse, Recombinant (His)
TMPY-01896
Species: Mouse
Expression System: HEK293
VISTA Protein, Human, Recombinant (His)
TMPY-03219
Species: Human
Expression System: HEK293
FOLR1 Protein, Human, Recombinant (hFc)
TMPJ-00147
Species: Human
Expression System: Human Cells
FGF-18 Protein, Human, Recombinant (His)
TMPY-02626
Species: Human
Expression System: HEK293
FGF-4 Protein, Human, Recombinant
TMPY-05004
Species: Human
Expression System: E. coli
FGF-21 Protein, Human, Recombinant
TMPY-06935
Species: Human
Expression System: E. coli
Syndecan-1 Protein, Human, Recombinant (His)
TMPY-01630
Species: Human
Expression System: HEK293
FGF-2 Protein, Mouse, Recombinant
TMPJ-00037
Species: Mouse
Expression System: E. coli
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
TMPY-01613
Species: Mouse
Expression System: HEK293
LIF Protein, Human, Recombinant
TMPY-04104
Species: Human
Expression System: HEK293
LIF Protein, Mouse, Recombinant
TMPY-04278
Species: Mouse
Expression System: HEK293
Alpha-fetoprotein Protein, Human, Recombinant (His)
TMPY-02509
Species: Human
Expression System: HEK293
Periostin/OSF-2 Protein, Human, Recombinant (His)
TMPY-01020
Species: Human
Expression System: HEK293
Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His)
TMPY-00663
Species: Human
Expression System: HEK293
LIF Protein, Human, Recombinant (His)
TMPY-03532
Species: Human
Expression System: HEK293
Cripto Protein, Human, Recombinant (His)
TMPY-01413
Species: Human
Expression System: HEK293
Noggin/NOG Protein, Mouse, Recombinant (His)
TMPJ-01065
Species: Mouse
Expression System: Human Cells
gp130/IL6ST Protein, Human, Recombinant (His & hFc)
TMPY-01076
Species: Human
Expression System: HEK293
gp130/IL6ST Protein, Mouse, Recombinant (His)
TMPY-01832
Species: Mouse
Expression System: HEK293
Pleiotrophin/PTN Protein, Mouse, Recombinant
TMPY-03577
Species: Mouse
Expression System: Baculovirus-Insect Cells
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Cat No. Product Name
L4300 Wnt/Hedgehog/Notch Compound Library

240 compounds
A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L1380 Transcription Factor-Targeted Compound Library

704 compounds
Well-chosen 704 compounds with unique structures targeting transcription factor;
L4100 TGF-beta/Smad Compound Library

185 compounds
A unique collection of 185 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;
L8000 Stem Cell Differentiation Compound Library

1213 compounds
A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening;

Libraries

Wnt/Hedgehog/Notch Compound Library
L4300
Compounds: 240
Transcription Factor-Targeted Compound Library
L1380
Compounds: 704
TGF-beta/Smad Compound Library
L4100
Compounds: 185
Stem Cell Differentiation Compound Library
L8000
Compounds: 1213
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