ecdysone

Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death.

Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.

Tebufenozide is a novel nonsteroidal ecdysone agonist. It shows good efficacy and playing an increasingly important role in the control of Lepidopteran pests.

Ponasterone A is an ecdysteroid with high affinity for the ecdysteroid receptor. It enables rapid switching on and off of reporter genes and is a potent regulator of gene expression in cells and transgenic animals.

β-Gentiobiose is a natural oligosaccharide that promotes fruit ripening.

Crustecdysone (Standard) is a reference standard for research and analysis in studies involving Crustecdysone. Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.

2-O-Acetyl-20-hydroxyecdysone is an ecdysone present in insects and terrestrial plants. 2-O-Acetyl-20-hydroxyecdysone inhibits amyloid-β42-induced cytotoxicity and is able to reduce the formation of Aβ oligomers by promoting fibrillogenesis, which converts Aβ oligomers into less toxic fibers.

3-O-Acetyl-20-Hydroxyecdysone, a steroid extracted from the roots of Cyanotis arachnoidea C.B.Clark, is characterized by its unique structural modifications.

20,26-Dihydroxyecdysone is a predominant ecdysteroid metabolite [1].

Halofenozide is an ecdysteroid agonist and used as a pesticide.

Insecticidal agent 9 (Compound I-17) is an insecticide with strong pest control properties. It exhibits LC50 values of 93.32 mg/L and 114.79 mg/L against Plutella xylostella and Ostrinia furnacalis, respectively. At a concentration of 500 mg/L, it achieves an 86.1% mortality rate for Spodoptera frugiperda. The compound effectively targets ecdysone receptors (EcR) and three chitinase enzymes (OfChtI, OfChtII, and OfChi-h), demonstrating excellent binding activity with EcR and inhibition rates for the chitinases. Insecticidal agent 9 is suitable for research in pest management.

Muristerone A, a phytoecdysteroid analog of ecdysone, is a potent ecdysteroid receptor agonist with a Kd of 1 nM [1].

RG-102240 is a ligand for the insect ecdysone receptor (EcR). Its IC50 values against wild-type G:CfE (DEF) and A110P mutant are 85 nM and 13 nM, respectively. It activates reporter gene expression of both wild-type CfEcR and the A110P mutant.

Makisterone A is a natural product exhibiting agonistic activity toward the ecdysone receptor in Sf-9 cells (IC50 = 112 nM).

Tebufenozide (Standard) is the standard substance of Tebufenozide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Tebufenozide is a novel nonsteroidal ecdysone agonist. It shows good efficacy and playing an increasingly important role in the control of Lepidopteran pests.