creatine

Creatine (Methylguanidoacetic acid) is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine. Creatine functions as part of the cell's energy shuttle. The high energy phosphate group of ATP is transferred to creatine to form phosphocreatine in the following reaction: Cr + ATP <-> PCr + ADP. This reaction is reversibly catalyzed by creatine kinase. In the human body, creatine is synthesized mainly in the liver by the use of parts from three different amino acids: arginine, glycine, and methionine. 95% of it is later stored in the skeletal muscles and the rest is stored in the brain, heart, and testes.

Creatine riboside, a urinary metabolite, is a diagnostic and prognostic biomarker of lung cancer.

Creatine-D3 (Standard) is a reference standard of Creatine-D3 intended for quantitative analysis, quality control, and related biochemical research applications. Creatine-d3 is an isotopically labeled version of creatine. Creatine is an endogenous amino acid metabolite that plays a crucial role in cellular energy, particularly within muscles and the brain.

Creatine-CoA (Creatine-coenzyme A) is a derivative of coenzyme A.

Creatine monohydrate (Methylguanidoacetic acid monohydrate) is a key player in the phosphagen energy system, especially in muscle and the brain. Creatine monohydrate is the primary source of ATP during high-intensity, short-term activities.

Phosphocreatine disodium (Phosphocreatine disodium salt) is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in muscle, skeletal, and brain.

Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) mainly exists in the skeletal muscles of vertebrates. It is a substrate for the determination of creatine kinase and can be used for the regeneration of ATP during skeletal muscle contraction.

Phosphocreatine dipotassium, primarily found in the skeletal muscles of vertebrates, is an organic compound categorized under alpha amino acids and derivatives.

Creatine-D3 hydrate is a deuterium labeled Creatine hydrate. Under physiological and in pathological conditions, Creatine hydrate (T22300) is pivotal in energy metabolism of muscle and brain cells.

Creatine-D3 Hydrate (Standard) is a reference standard of Creatine-D3 Hydrate intended for quantitative analysis, quality control, and related biochemical research applications. Creatine-d3 hydrate (CREATINE-(METHYL-D3) MONOHYDRATE) is a deuterium labeled Creatine hydrate. Under physiological and in pathological conditions, Creatine hydrate is pivotal in energy metabolism of muscle and brain cells.

Creatine Kinase (CK/CPK), Porcine Heart (CPK, CK, Creatine Phosphokinase), serves as a biological material or organic compound applicable in life sciences research.

Creatine Kinase (CPK/CK), Bovine Heart (CK, CPK, Creatine Phosphokinase), is a biological material or organic compound suitable for use in life sciences research.

RGX-202 (β-GPA) is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARγ coactivator 1α (PGC-1α).

Creatine-D3 is an isotopically labeled version of creatine. Creatine (T4883) is an endogenous amino acid metabolite that plays a crucial role in cellular energy, particularly within muscles and the brain.

Creatine ethyl ester (CEE) is a readily available form of creatine commonly used in supplements. It can upregulate TLRs (TLR2, 3, 4, and TLR7) over a short period.

Creatine ethyl ester hydrochloride is a biologically active compound that can be utilized for life science research applications.

Creatine kinase (OcCK) catalyzes the reversible reaction of creatine and ATP to form phosphocreatine and ADP. Creatine kinase (OcCK) is a key enzyme for maintaining a constant ATP/ADP ratio during rapid energy turnover [1] .

Creatine-13C is Creatine (TMIM-00056) labeled with 13C. Creatine, an endogenous amino acid metabolite, plays a crucial role in cellular energy, particularly in muscle and brain tissues.

Creatine (Standard) is a naturally occurring nitrogenous organic acid that is stored in the body primarily as Creatine Phosphate, an important source of rapid intracellular energy supply.Creatine has neuroprotective and cardiovascular protective effects, and exerts anti-inflammatory activity through inhibition of TNF-alpha expression. As a standard, Creatine can be used for quantitative analysis to study energy metabolic pathways and related diseases.

Creatine monohydrate (Standard) is the analytical standard of Creatine (monohydrate), primarily used for quantitative analysis and metabolic research. Creatine is an endogenous amino acid metabolite synthesized from arginine, glycine, and methionine. It plays a fundamental role in cellular energy metabolism, particularly within tissues with high and fluctuating energy demands like skeletal muscle and the brain. Through the action of creatine kinase (CK), creatine is phosphorylated to phosphocreatine (PCr), serving as a rapid energy buffer to regenerate ATP from ADP, thereby maintaining cellular energy homeostasis during intense activity or metabolic stress.

Creatine Kinase MB (rCK-MB), Recombinant Human (CK-MB), serves as a biological material or organic compound applicable in life science research.

Creatine Kinase BB (CK-BB) Isoenzyme, derived from Porcine Brain (also known as CPK-1, CKBB isoenzyme, CK-BB), serves as a valuable biological material or organic compound for life science research.

Creatine Kinase MM (CK-MM), Human Skeletal Muscle (CK-MM, CKMM), serves as a biomaterial or organic compound applicable in life science research.

Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation, improving cognitive, autistic and epileptic phenotypes in mouse models of creatine transporter deficiency (CTD).