cis-Vitamin K1

Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] .

8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car is a H+/K+ ATPase inhibitor with IC50 of 0.38μM.

Vitamin K1 (Phylloquinone) a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.

K-Ras-IN-1 is a K-Ras inhibitor.

Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.

9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer resulting from the interaction of vitamin A palmitate in corn flakes. It exhibits a biological activity of 26% compared to all-trans-vitamin A palmitate, which is known to be the most biologically active form of vitamin A.

PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.

High affinity and potent ghrelin receptor inverse agonist (Ki values are 4.9 and 31 nM in COS7 and HEK293T cells, respectively). Blocks ghrelin receptor-mediated Gq- and G13-dependent signaling pathways.

Vitamin K1-d4 is a deuterated compound of Vitamin K1. Vitamin K1 has a CAS number of 84-80-0. Vitamin K1 (Phylloquinone) is a naturally-occurring vitamin. Vitamin K1 is essential for blood clotting, bone and vascular metabolism.

Vitamin K (Kephton) has blood coagulation action and is important for coagulation factors, matrix-Gla protein, and osteocalcin.

K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.

13-cis-Vitamin A palmitate (13-cis-Retinyl palmitate), a derivative of vitamin A palmitate found in corn flakes, is the 13-cis isomer exhibiting 75% of the biological activity of all-trans-vitamin A palmitate, which is the most active form of vitamin A [1].

cis-1-Benzyl-4-(methoxycarbonyl)pyrrolidine-3-carboxylic acid is a Other heterocyclic compound - pyrrolidine, building block - electrophile.

cis MZ 1 is a negative Control for MZ1. Exhibits no significant VHL binding affinity.

Vitamin K1 2,3-epoxide (Phylloquinone oxide) is reduced to vitamin k and is involved in the vitamin k cycle.

cis-8-Dodecen-1-ol is a Grapholita molesta inducer, a sex pheromone component of female Grapholita molesta, commonly used in agriculture.

Vitamin K1-d7 is a deuterated compound of Vitamin K1.

cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) is an aroma compound which typically described as green grassy or the smell of cut grass . cis-3-Hexen-1-ol has been found in many fresh fruits and vegetables and widely used as an added flavor in processed food and perfume. cis-3-Hexen-1-ol is also an attractant to various insects[1][2].

K-(D-1-Nal)-FwLL-NH2 TFA is a potent and high-affinity inverse agonist of the ghrelin receptor, exhibiting Ki values of 4.9 nM in COS7 cells and 31 nM in HEK293T cells. This compound effectively inhibits ghrelin receptor-mediated Gq- and G13-dependent signaling pathways.

K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).

K-Ras ligand-Linker Conjugate 1 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker, facilitating the recruitment of E3 ligases VHL, CRBN, MDM2, and IAP. It can be utilized in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].

ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases.