chloramphenicol

Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Chloramphenicol acts primarily on the 50S subunit of the bacterial 70S ribosome and is active against peptidyltransferases, inhibiting the formation of peptide bonds.

Chloramphenicol palmitate is a broad-spectrum antibiotic with activity against gram-positive and gram-negative bacteria. Chloramphenicol palmitate can be used in studies about acting as a bacterial selection agent in transformed cells containing chloramphenicol resistance genes.

Chloramphenicol stearate is an antibiotic useful for the therapy of numbers of bacterial infections. This includes an eye ointment to treat conjunctivitis.

Dextramycine is an optic isomer of chloramphenicol.

Chloramphenicol succinate sodium is broad-spectrum antibiotic with antibacterial activity.

L-erythro-Chloramphenicol functions as a potent inhibitor of electron transport.

Chloramphenicol succinate is a water-soluble prodrug of Chloramphenicol, a bacteriostatic antibiotic that binds to bacterial ribosomes to block their translation. CPSA is a competitive substrate and inhibitor of succinate dehydrogenase (SDH). In vitro, Kemicetine succinate can be oxidized by succinate dehydrogenase to release chloramphenicol.

m-Chloramphenicol (m-threo-Chloramphenicol), an impurity of Chloramphenicol, is a broad-spectrum antibiotic known for its potent capability to inhibit bacterial protein biosynthesis [1].

Chloramphenicol-d5 is a deuterated compound of Chloramphenicol. Chloramphenicol has a CAS number of 56-75-7. Chloramphenicol, a broad-spectrum antibiotic, blocks bacterial protein synthesis.

Chloramphenicol (Standard) is the standard substance of Chloramphenicol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Chloramphenicol acts primarily on the 50S subunit of the bacterial 70S ribosome and is active against peptidyltransferases, inhibiting the formation of peptide bonds.

Chloramphenicol-d5 (Standard) is the standard substance of Chloramphenicol-d5, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Chloramphenicol-d5 is a deuterated compound of Chloramphenicol. Chloramphenicol has a CAS number of 56-75-7. Chloramphenicol, a broad-spectrum antibiotic, blocks bacterial protein synthesis.

Chloramphenicol acetate, an acetylated and inactive derivative of chloramphenicol, is synthesized in E. coli and S. aureus through the action of the inducible enzyme chloramphenicol acetyltransferase, utilizing acetyl coenzyme A (acetyl-CoA), to impart resistance to chloramphenicol. This compound exhibits no antibiotic activity against S. sonnei in turbidimetric assays.

Chloramphenicol 3-O-β-D-glucuronide is a biochemical reagent utilized in glycobiology research. Glycobiology focuses on the structure, synthesis, biology, and evolution of sugars, involving carbohydrate chemistry, glycans' formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to fundamental research, biomedicine, and biotechnology.

Rose Bengal Chloramphenicol Agar is a selective medium designed for counting yeasts and molds in a variety of foods. The medium maintains a neutral pH, and chloramphenicol serves as a selective agent to inhibit bacterial growth.

Chloramphenicol-BSA is a hapten-carrier protein conjugate formed by coupling Chloramphenicol to bovine serum albumin (BSA). As a hapten, Chloramphenicol alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. Chloramphenicol-BSA may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M TBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

Chloramphenicol-OVA is a hapten-carrier protein conjugate formed by coupling Chloramphenicol to chicken Ovalbumin (OVA). As a hapten, Chloramphenicol alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. Chloramphenicol-OVA may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M TBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

Thiamphenicol (Dextrosulphenidol) is a methylsulfonyl analog of chloramphenicol. It is an antibiotic and immunosuppressive agent.

Levomecol, a broad-spectrum antibiotic derived from Streptomyces venezuelae, comprises Chloramphenicol and Methyluracil. It exerts its bacteriostatic effect by binding to the bacterial ribosome, inhibiting protein synthesis by blocking peptidyl transferase.

Azidamfenicol inhibits ribosomal peptidyltransferase with a Ki of 22 µM. Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic.

Furalazine is an antimicrobial agent. Furalazine was more effective in reducing the duration of positive stool culture than chloramphenicol. It may be potentially used in the treatment of cholera.

Bromamphenicol is a dibrominated derivative of the antibiotic chloramphenicol. It inhibits rat liver mitochondrial and E. coli protein synthesis by 90.6 and 98.8%, respectively, when used at a concentration of 93 μM, and inhibits DNA synthesis in human lymphoblastoid cells by 83% at 1 mM. Bromamphenicol can also bind to the major adhesin subunit DraE from E. coli.

Corynecin V is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.

Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneumoniae, and S. aureus among others.

Corynecin III is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It inhibits the growth of Gram-positive and Gram-negative bacteria, including S. faecalis, S. aureus, B. subtilis, E. coli, P. aeruginosa, P. vulgaris, S. sonnei, S. typhosa, and K. pneumoniae (MICs = 2.6-83 μg/ml).