candesartan

Candesartan (CV 11974) is an angiotensin II receptor blocker widely used in the treatment of hypertension and heart failure.

Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). Upon hydrolysis to candesartan during gastrointestinal absorption, it selectively competes with angiotensin II for binding to the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation.

Methyl candesartan (Candesartan Methyl Ester) is a potent angiotensin 2 receptor antagonist used in the study of hypertension.

Candesartan-d4 is the deuterated form of Candesartan. It is an orally active Angiotensin II AT1 receptor blocker and PPAR-γ agonist with long-lasting antihypertensive effects, used as an internal standard in PK studies.

1H-1-ethyl Candesartan Cilexetil is a process-related impurity in the bulk synthesis of candesartan cilexetil, which is a potent, long-acting and selective angiotensin II type 1 receptor (AT1) antagonist.

Candesartan-D4 (Standard) is a reference standard of Candesartan-D4 intended for quantitative analysis, quality control, and related biochemical research applications.

Trityl candesartan is a crucial intermediate used in the synthesis of Candesartan and Candesartan cilexetil, which are angiotensin II receptor antagonists.

Candesartan (Standard) is a reference standard for research and analysis in studies involving Candesartan. Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.