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Search Results for " cancer-initiating "

Targets

6

Compounds

39

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T2345 PTC-209 PTC209,PTC 209 BMI-1 , Autophagy
PTC-209 is a potent and selective BMI-1 inhibitor.
T6178 PTC-209 hydrobromide PTC-209 HBr BMI-1 , Autophagy
PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).
T38637 Roy-Bz
Roy-Bz is a potent and selective activator of protein kinase C delta (PKCδ). It effectively inhibits proliferation in colon cancer cells by initiating a mitochondrial apoptotic pathway that relies on PKCδ and involves th...
T36485 Becatecarin
Becatecarin is a water-soluble, diethylaminoethyl analog of the antineoplastic antibiotic rebeccamycin. It intercalates into DNA, stabilizing the DNA-topoisomerase complex. This results in the potent catalytic inhibition...
T35940 Darinaparsin Dimethylarsinic glutathione,Darinaparsin
Darinaparsin is a dimethylated arsenic linked to glutathione. It is cytotoxic to DU145, LNCaP, and PC3 prostate cancer cells (IC50s = 5-10 &#181M) and patient-derived primary prostate cancer cells (IC50s = 2.5-20 &#181M)...
T79558 Fac-[Re(CO)3(L3)(H2O)][NO3]
Fac-[Re(CO)3(L3)(H2O)][NO3] (Compound 3), a rhenium(I) tricarbonyl aqua complex, acts as an anticancer agent through the induction of mitochondrial dysfunction. It exhibits cytotoxicity against prostate cancer cells, dem...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01730 CD24 Protein, Human, Recombinant (hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03016 CD24 Protein, Mouse, Recombinant (hFc) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-04976 PDGFC Protein, Mouse, Recombinant (His) Mouse Yeast
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-00731 Cathepsin B Protein, Human, Recombinant (His) Human HEK293
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...
TMPK-01381 CSPG4/MCSP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The chondroitin sulfate proteoglycan-4 (CSPG4) is a cell surface proteoglycan overexpressed in a huge range of human and canine neoplastic lesions by tumor cells, tumor microenvironment and cancer initiating cells. CSPG4...
TMPK-00993 Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His) Canine HEK293
Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via in...
TMPK-01365 CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His & AVI), Biotinylated Human HEK293
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protecti...
TMPK-01366 CA125/MUC16 Protein, Human, Recombinant (aa 12660-12923, His & AVI), Biotinylated Human HEK293
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protecti...
TMPK-01359 CA125/MUC16 Protein, Human, Recombinant (His & Avi) Human HEK293
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protecti...
TMPK-01394 CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His) Human HEK293
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protecti...
TMPY-05298 CD24 Protein, Human, Recombinant (rFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-06940 CD24 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03032 CD24 Protein, Rat, Recombinant (hFc) Rat HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05299 CD24 Protein, Human, Recombinant (mFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00977 LEPR Protein, Mouse, Recombinant (mFc) Mouse Human Cells
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPY-03590 PDGFRB Protein, Rhesus, Recombinant (His) Rhesus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01207 PDGFRB Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05497 PDGFRB Protein, Human, Recombinant (hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00975 LEPR Protein, Mouse, Recombinant (hFc) Mouse Human Cells
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPY-03474 PDGFRB Protein, Rat, Recombinant (hFc) Rat HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00976 LEPR Protein, Mouse, Recombinant (His) Mouse Human Cells
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPY-04937 PDGFRB Protein, Human, Recombinant (His), Biotinylated Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05358 PDGFRB Protein, Human, Recombinant Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00411 LEPR Protein, Human, Recombinant (hFc) Human Human Cells
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPY-03140 PDGFRB Protein, Rat, Recombinant (His) Rat HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00385 PDGFRB Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00898 PDGFC Protein, Human, Recombinant (hFc) Human HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-05252 Myeloperoxidase/MPO Protein, Human, Recombinant (His) Human HEK293
MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important en...
TMPY-02251 PDGFC Protein, Mouse, Recombinant (hFc) Mouse HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-00269 PDGFC Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-02815 PDGFC Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-04408 CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in pro...
TMPY-06938 FLT3 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-05738 FLT3 Protein, Human, Recombinant (hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-03704 FLT3 Protein, Mouse, Recombinant (His) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-04503 Cathepsin B Protein, Rat, Recombinant (His) Rat HEK293
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...
TMPY-02144 Cathepsin B Protein, Mouse, Recombinant (His) Mouse HEK293
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...
TMPY-01576 Artemin Protein, Mouse, Recombinant (hFc) Mouse HEK293
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored...
CD24 Protein, Human, Recombinant (hFc)
TMPY-01730
Species: Human
Expression System: HEK293
CD24 Protein, Mouse, Recombinant (hFc)
TMPY-03016
Species: Mouse
Expression System: HEK293
PDGFC Protein, Mouse, Recombinant (His)
TMPY-04976
Species: Mouse
Expression System: Yeast
FLT3 Protein, Human, Recombinant (T227M, His)
TMPY-01247
Species: Human
Expression System: HEK293
Cathepsin B Protein, Human, Recombinant (His)
TMPY-00731
Species: Human
Expression System: HEK293
CSPG4/MCSP Protein, Cynomolgus, Recombinant (His)
TMPK-01381
Species: Cynomolgus
Expression System: HEK293
Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)
TMPK-00993
Species: Canine
Expression System: HEK293
CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His & AVI), Biotinylated
TMPK-01365
Species: Human
Expression System: HEK293
CA125/MUC16 Protein, Human, Recombinant (aa 12660-12923, His & AVI), Biotinylated
TMPK-01366
Species: Human
Expression System: HEK293
CA125/MUC16 Protein, Human, Recombinant (His & Avi)
TMPK-01359
Species: Human
Expression System: HEK293
CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His)
TMPK-01394
Species: Human
Expression System: HEK293
CD24 Protein, Human, Recombinant (rFc)
TMPY-05298
Species: Human
Expression System: HEK293
CD24 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06940
Species: Human
Expression System: HEK293
CD24 Protein, Rat, Recombinant (hFc)
TMPY-03032
Species: Rat
Expression System: HEK293
CD24 Protein, Human, Recombinant (mFc)
TMPY-05299
Species: Human
Expression System: HEK293
LEPR Protein, Mouse, Recombinant (mFc)
TMPJ-00977
Species: Mouse
Expression System: Human Cells
PDGFRB Protein, Rhesus, Recombinant (His)
TMPY-03590
Species: Rhesus
Expression System: HEK293
PDGFRB Protein, Human, Recombinant (His)
TMPY-01207
Species: Human
Expression System: HEK293
PDGFRB Protein, Human, Recombinant (hFc)
TMPY-05497
Species: Human
Expression System: HEK293
LEPR Protein, Mouse, Recombinant (hFc)
TMPJ-00975
Species: Mouse
Expression System: Human Cells
PDGFRB Protein, Rat, Recombinant (hFc)
TMPY-03474
Species: Rat
Expression System: HEK293
LEPR Protein, Mouse, Recombinant (His)
TMPJ-00976
Species: Mouse
Expression System: Human Cells
PDGFRB Protein, Human, Recombinant (His), Biotinylated
TMPY-04937
Species: Human
Expression System: HEK293
PDGFRB Protein, Human, Recombinant
TMPY-05358
Species: Human
Expression System: HEK293
LEPR Protein, Human, Recombinant (hFc)
TMPJ-00411
Species: Human
Expression System: Human Cells
PDGFRB Protein, Rat, Recombinant (His)
TMPY-03140
Species: Rat
Expression System: HEK293
PDGFRB Protein, Rhesus, Recombinant (hFc)
TMPY-00385
Species: Rhesus
Expression System: HEK293
PDGFC Protein, Human, Recombinant (hFc)
TMPY-00898
Species: Human
Expression System: HEK293
Myeloperoxidase/MPO Protein, Human, Recombinant (His)
TMPY-05252
Species: Human
Expression System: HEK293
PDGFC Protein, Mouse, Recombinant (hFc)
TMPY-02251
Species: Mouse
Expression System: HEK293
PDGFC Protein, Cynomolgus, Recombinant (hFc)
TMPY-00269
Species: Cynomolgus
Expression System: HEK293
PDGFC Protein, Human, Recombinant (His)
TMPY-02815
Species: Human
Expression System: Baculovirus-Insect Cells
CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)
TMPY-04408
Species: Human
Expression System: Baculovirus-Insect Cells
FLT3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06938
Species: Human
Expression System: HEK293
FLT3 Protein, Human, Recombinant (hFc)
TMPY-05738
Species: Human
Expression System: HEK293
FLT3 Protein, Mouse, Recombinant (His)
TMPY-03704
Species: Mouse
Expression System: HEK293
Cathepsin B Protein, Rat, Recombinant (His)
TMPY-04503
Species: Rat
Expression System: HEK293
Cathepsin B Protein, Mouse, Recombinant (His)
TMPY-02144
Species: Mouse
Expression System: HEK293
Artemin Protein, Mouse, Recombinant (hFc)
TMPY-01576
Species: Mouse
Expression System: HEK293
TargetMol