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Results for "
cadp-ribose
" in TargetMol Product Catalog- Inhibitors & Agonists2
Cyclic ADP-Ribose (ammonium salt)
Cyclic ADP-Ribose ammonium, cADP-Ribose ammonium, cADPR ammonium
T37475
Cyclic ADP-Ribose (ammonium salt) (cADPR) is an endogenous NAD⁺ metabolite that triggers Ca²⁺ release from ER stores via ryanodine receptors and is synthesized by CD38 and CD157. It may also activate TRPM2 in a temperature-dependent manner. Showing potential in research related in inflammation and immunology.
- $538
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8-bromo-Cyclic ADP-Ribose (sodium salt)
T37803
Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, which in turn activate ryanodine receptors. 8-bromo-cADP-Ribose is a stable, cell-permeable analog that blocks calcium release evoked by cADP-ribose in sea urchin egg homogenates with an IC50 value of 1.7 μM. It is commonly used to investigate intracellular signaling through cADP-ribose in isolated cells and tissues.
- $589
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