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  • GABA Receptor
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bzr

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  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
TCS 1105
N-(4-fluorobenzyl)-2-(1H-indol-3-yl)-2-oxoacetamide
T23444185391-33-7
TCS 1105 is a GABAA benzodiazepine receptor (BZR) ligand. TCS 1105 blocks Sema3A induced axonal growth cones collapse. TCS 1105 reduces anxiety-like behavior and enhances offensive behavior and social dominance in mice.
  • $34
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TargetMol | Inhibitor Sale
Ro15-4513
T1677591917-65-6
Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist.
  • $143
5 days
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GABA-IN-4
T20550161-38-1
GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.
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10-14 weeks
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Anxiolytic/nonsedative agent-1
TCS 1205
T23445355022-97-8
Anxiolytic nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.
  • $58
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