bifunctional

Cy5-bifunctional dye TEA (146368-15-2 free base) is a water-soluble far-infrared cyanine fluorescent dye(Ex/Em=650/670 nM，). It is characterized by high fluorescence intensity, photostability, and biocompatibility. Cy5-bifunctional dye TEA (146368-15-2 free base) can be used for the aqueous-phase labeling of proteins, antibodies, and nucleic acids. Cy5-bifunctional dye TEA (146368-15-2 free base) can also be used for live-cell imaging and in vivo tumor imaging.

Sulfo-Cy3 diacid NHS ester is a CY3-derived dye. Cy3 (Sulfo-Cyanine3) is an amine-reactive cyanine orange dye with Ex/Em=550/570 nm, commonly used for fluorescent labelling of proteins and nucleic acids.

Cy5-bifunctional dye potassium is a water-soluble bifunctional dye with two NHS ester terminal groups. The NHS ester can react specifically and efficiently under neutral or mildly alkaline conditions with primary amines, such as lysine residue side chains or amino silane-coated surfaces, forming covalent bonds. This dye is applicable for amine cross-linking and other advanced labeling applications.

Cy5-bifunctional dye is a derivative of CY5. CY5 is an amine-reactive fluorophore with excitation/emission wavelengths of 650/670 nm, commonly employed for labelling nucleic acids and proteins.

4-(2-Azidoethyl)phenol is a bifunctional small molecule probe featuring both a phenolic hydroxyl group and an azide structure. Its core application lies in the phenol moiety serving as a substrate for APEX2 (ascorbate peroxidase), generating reactive radicals in situ in the presence of H₂O₂ to label neighboring proteins. Concurrently, the terminal azide group can be linked to alkyne-labeled detection molecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) to achieve biotinylation or fluorescence visualization. 4-(2-Azidoethyl)phenol is widely used in proximity labeling-based proteomics research.

PE-VF750 Maleimide is a bifunctional dye designed for thiol reactions, featuring a maleimide group that enables covalent bonding with thiol groups. It possesses an excitation/emission (Ex/Em) profile of 495-566/777 nm. The individual dyes PE and VF within PE-VF750 Maleimide have excitation wavelengths of 495 nm and 566 nm, respectively. The emission wavelength (Em) for PE-VF594 Maleimide is 777 nm.

PE-VF680 Maleimide is a bifunctional dye known for its capability to undergo thiol reactions, featuring a maleimide group that reacts with thiol groups to form covalent bonds. Its excitation/emission (Ex/Em) spectrum is 495-566/701 nm. The two dyes within PE-VF680, PE and VF, have excitation wavelengths (Ex) of 495 nm and 566 nm, respectively, with PE-VF594 Maleimide exhibiting an emission wavelength (Em) of 701 nm.

Biotin-PEG-Biotin (MW 20000) is a bifunctional PEG derivative with biotin labels at each terminal end. Biotin facilitates protein labeling as an enzyme co-factor, while the hydrophilic and low-toxicity nature of PEG imparts water solubility to the compound.

Aminomethyltrioxsalen hydrochloride, a Psoralen derivative, penetrates intact cells and, upon ultraviolet light irradiation, creates interstrand crosslinks between pyrimidine residues in nucleic acid helices. As a bifunctional nucleic acid intercalating agent, it serves as a probe for identifying double-stranded regions in heterogeneous nuclear RNA (hnRNA) to analyze its secondary structure.