bcs

Triafamone is a new sulfonanilide herbicide.

TNO155 is a protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11) inhibitor(IC50 : 0.011 µM),with potential antineoplastic activity.

bCSE-IN-1 (Compound 3i) is an inhibitor of bacterial cystathionine γ-lyase (Bacterial Cystathionine γ-Lyase) and exhibits antibacterial (antibacterial) activity.

UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)

Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity

MAC-VC-PABC-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].

DBCO-HS-PEG2-VA-PABC-SG3199 is a drug-linker conjugate for ADC (antibody-drug conjugate) that features a SG3199-based DNA minor groove cross-linking agent and a cleavable linker. This compound is suitable for the synthesis of ADCs.

Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel that ameliorates RBC dehydration in the SAD mouse. It blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 = 100 ± 12 nM) and inhibits RBC dehydration with an IC50 of 30 ± 20 nM. Senicapoc is used in the treatment of Sickle Cell Disease and Sickle Cell Anemia.

MC-VC-PABC-SP 141 is a potent antitumor conjugate for antibody-drug conjugation (ADC), featuring SP 141, a robust MDM2 inhibitor, connected through the cleavable linker [MC-VC-PABC], facilitating targeted cancer therapy.

BCN-HS-PEG2-VA-PABC-SG3199 (Compound 4) functions as a pyrrolobenzodiazepine-based agent linker for antibody-drug conjugates (ADC) [1]. This compound also serves as a click chemistry reagent, featuring a BCN group capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.

Fast garnet GBC sulfate salt, 90% (Azoic diazo No. 4, 90%), is a chromogenic substrate for alkaline phosphatase.

Pegulicianine is an imaging agent utilized to detect residual cancer cells in the tumor bed of female patients undergoing breast-conserving surgery (BCS).

EST64454 is a σ1 receptor (σ1R) antagonist clinical candidate for the treatment of pain. EST64454 shows an outstanding aqueous solubility, which together with its high permeability in Caco-2 cells will allow its classification as a BCS class I compound. It also shows high metabolic stability.

Bathocuproine disulfonate disodium (BCS) is an organic compound utilized as a highly sensitive colorimetric reagent for copper ions in biochemical and analytical applications. Its bright yellow color and specific light absorption make it effective for detecting and quantifying trace amounts of copper. In biochemistry, BCS is commonly employed to study the role of copper ions in various biological processes. Copper, being an essential nutrient for many organisms, can be toxic at high concentrations, thus precise measurement is crucial to understanding its impact on living systems. Analytically, BCS is often used for environmental monitoring and assessing copper pollution in water quality testing. It can detect copper even at very low concentrations, making it a valuable tool for identifying potential contamination sources and evaluating the impact of industrial activities on aquatic ecosystems.