apoa1

Expression system: E. coli
Length: 25-265, Partial
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 25-265, Partial
Activity: Not Tested

Expression system: E. coli
Length: 19-267, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-264, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 25-264, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-267, Full Length
Activity: ELISA

Expression system: E. coli
Length: 25-267, Partial
Activity: Not Tested

APOA1BP, now renamed NAXE, encodes an epimerase essential in the cellular metabolite repair for NADHX and NADPHX. The enzyme catalyzes the epimerization of NAD(P)HX, thereby avoiding the accumulation of toxic metabolites.Pathogenic biallelic mutations in NAXE in children from four families with (sub-) acute-onset ataxia, cerebellar edema, spinal myelopathy, and skin lesions.

Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA1 (aa 36-68) contains putative fibronectin- and laminin-binding motifs. This region also binds heparin sulfate proteoglycans at mildly acidic pH and promotes aggregation of A-SAA.

Expression system: HEK293 Cells
Length: 1-396, Full Length
Activity: Not Tested