antimicrobial agent-26

Antimicrobial agent-26 is a powerful antimicrobial that has demonstrated the ability to counteract antibiotic resistance in vitro [1].

Antibacterial agent 26 is an antimicrobial compound that is a potent DHFR inhibitor (S. aureus DHFR Ki of 0.020 nM).

Antibacterial agent 243 is a potent antimicrobial compound with EC50 values of 0.64 mg L for Valsa mali, 26 mg L for allicin, and 0.33 mg L for tebuconazole. It induces hyphal contraction and collapse, triggers the accumulation of reactive oxygen species within cells, modulates antioxidant enzyme activity, initiates lipid peroxidation, and ultimately causes irreversible oxidative damage to Valsa mali cells.

Vitamin K5 (Synkamin), a photosensitizer and antimicrobial agent, serves as a specific PKM2 inhibitor, demonstrating IC 50 values of 28, 191, and 120 μM against PKM2, PKM1, and PKL, respectively. It induces apoptosis in colon 26 cells and is utilized in infection and cancer research. Additionally, Vitamin K5 finds application as a preservative in pharmaceuticals, foods, and beverages [1] [2] [3].