antiallodynic

Inosine (NSC-20262) is an endogenous purine nucleoside produced from the metabolic breakdown of adenosine. It is an agonist of adenosine receptors A1R and A2AR, possessing anti-inflammatory, immunomodulatory, cytoprotective, and neuroprotective effects, and can be used to establish hyperuricemia models.

L-DOPA (Levodopa) is an orally active metabolic precursor of the neurotransmitter dopamine. It can cross the blood-brain barrier and be converted into dopamine in the brain. L-DOPA exhibits anti-hyperalgesic effects and holds potential in Parkinson’s disease research, and it can also be used to induce Parkinson’s disease models.