anaerobic infections

Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Chloramphenicol acts primarily on the 50S subunit of the bacterial 70S ribosome and is active against peptidyltransferases, inhibiting the formation of peptide bonds.

Alalevonadifloxacin is a DNA gyrase and DNA topoisomerase inhibitor and a novel antibacterial compound of the quinolone class targeting MRSa. Alalevonadifloxacin is potentially useful in the treatment of bacterial Gram-positive, Gram-negative and anaerobic infections.

Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.

Tinidazole (CP12574)a is a 5-nitroimidazole derivative with the antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitrite anions and metronidazole. Metronidazole's nitro group, in turn, is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and DNA strand breaks with multiple hits having an additive effect and ultimately leading to cell death.

Metronidazole Benzoate (Benzoyl metronidazole) is a derivative of Metronidazole and benzoic acid, which has antibacterial, anti-parasitic and anti-trichomonas functions and is often used to treat infections caused by anaerobic bacteria.

Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and Gram-positive bacteria, and is commonly used in abdominal cavity infections, pelvic infections, and certain types of gynecological infections, and is highly effective against anaerobic bacteria.

Morinidazole shows antibacterial activity and can be used in studies about bacterial infections research such as appendicitis and pelvic inflammatory disease caused by anaerobic bacteria.

Omadacycline tosylate (PTK 0796 tosylate) is an orally administered aminocyclitol antibacterial agent and tetracycline antibiotic exhibiting broad-spectrum antimicrobial activity against Gram-positive, Gram-negative, anaerobic, and atypical pathogens. Omadacycline tosylate binds to the 30S ribosomal subunit of bacteria to inhibit protein synthesis and may be employed in studies of pneumonia and cutaneous infections.

Omadacycline (Amadacycline), a new tetracycline antibiotic, can inhibit the 30s subunit of bacterial ribosome.

Metronidazole hydrochloride (SC 326421), an orally active nitroimidazole antibiotic, is effective for researching anaerobic infections. This compound is capable of crossing the blood-brain barrier and may cause inflammation and skeletal muscle contraction with long-term use [1] [2] [3] [4].

Sitafloxacin hydrochloride (DU6859a), a potent fluoroquinolone antibiotic with oral activity, demonstrates antichlamydial activity and a broad antibacterial spectrum against gram-positive, gram-negative, and anaerobic bacteria, in addition to atypical pathogens. It is utilized in researching respiratory tract and urinary tract infections [1] [2].

Sitafloxacin (DU6859a) monohydrate is a potent oral fluoroquinolone antibiotic with antichlamydial and broad-spectrum antibacterial activities against gram-positive, gram-negative, anaerobic bacteria, and atypical pathogens, effective in researching respiratory and urinary tract infections [1] [2].

Metronidazole-d4 is a deuterium labeled compound for Metronidazole, which can be used for isotopic tracing.Metronidazole is a synthetic nitroimidazole derivative, an antibiotic and antiprotozoal agent with oral activity and blood-brain-barrier penetration for infections caused by anaerobic bacteria.

Metronidazole-d4 (Standard) is the standard substance of Metronidazole-d4, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Metronidazole-d4 is a deuterium labeled compound for Metronidazole, which can be used for isotopic tracing.Metronidazole is a synthetic nitroimidazole derivative, an antibiotic and antiprotozoal agent with oral activity and blood-brain-barrier penetration for infections caused by anaerobic bacteria.