albendazole

Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.

Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.

Albendazole-d3, a deuterated compound of Albendazole, is an anthelmintic and can be used to study the metabolism of Albendazole in vivo.

Albendazole sulfoxide D3 is deuterium-labeled Albendazole sulfoxide. Albendazole sulfoxide is a broad-spectrum anthelmintic.

Albendazole sulfone is a metabolite of albendazole with antiparasitic and anthelmintic activity, exhibiting cytotoxicity against the human hepatocellular carcinoma cell line HuH-7 with a CC50 < 5 µM.

Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helminths, including liver flukes, tapeworms, and roundworms. It eliminates Trichostrongylus in the fourth stomach of cattle and sheep when orally administered at doses ranging from 2.5 to 10 mg kg as well as other species in the fourth stomach and the small and large intestine. Albendazole (0.05% in the diet) protects mice against lethal infection with A. suum larvae. It also inhibits growth of HT-29 human colorectal cancer cells (IC50 = 0.12 µM), halts the cell cycle at the G2 M phase, and induces apoptosis. In an HT-29 mouse xenograft model, it inhibits peritoneal tumor growth when administered intraperitoneally at a dose of 150 mg kg but not when administered orally. Albendazole inhibits mammalian tubulin polymerization and inhibits binding of [3H]mebendazole t......

Albendazole sulfone-d3 is a deuterated compound of Albendazole sulfone.

ABZ-amine (Amino albendazole) is an impurity of Albendazole, a drug indicated for treating various worm infestations.

AHR-5333 mandelate is an anti-allergy compound which has been shown to protect against antigen-induced anaphylactic collapse and ascaris antigen-induced skin hypersensitivity. AHR-5333 mandelate has also been shown to inhibit 5-HETE, LTB4 and LTC4 synthesis.