z-isomer — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2280	Endoxifen (Z-isomer)	Endoxifen Z-isomer	Estrogen Receptor/ERR , EGFR , Potassium Channel , Estrogen/progestogen Receptor , HER
	Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptors that also inhibits aromatase activity.
T11766	Eltanexor Z-isomer	KPT-8602 (Z-isomer)	Others
	Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively.Eltanexor Z-isomer is the less active isomer of KPT-8602. KPT-8602 is a...		Others
T6827	Endoxifen Z-isomer hydrochloride	Endoxifen HCl	Estrogen Receptor/ERR , Potassium Channel , Estrogen/progestogen Receptor , HER
	Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
T1816	(Z)-JIB-04	NSC 693627,Z-JIB-04	Others
	(Z)-JIB-04 (NSC 693627) is an isomer of JIB-04.		Others
T11200	Endoxifen (E-isomer)	E-Endoxifen,Endoxifen E-isomer	Estrogen Receptor/ERR
	Endoxifen E-isomer (E-Endoxifen) is the E-isomer of (Z)-Endoxifen. Endoxifen E-isomer has antiestrogenic effects.		Estrogen Receptor/ERR
T16032L	(Z)-MDL 105519		Others
	(Z)-MDL 105519 is an inactive isomer of MDL105519.		Others
T8137	(Z)-Aconitic acid	Cls-Aconitic acid	Others , Endogenous Metabolite
	(Z)-Aconitic acid is the cis-isomer of Aconitic acid.is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.		Others , Endogenous Metabolite
T1109	(Z)-Capsaicin	Zucapsaicin,Civamide,cis-Capsaicin	TRP/TRPV Channel , HSV
	(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeutic efficacy in pain ac...		TRP/TRPV Channel , HSV
T13380	(Z)-Pitavastatin calcium		Others
	(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent of hydroxymethylglutaryl-CoA (HMG-CoA) reductase.		Others
T12611	R 80123		Others
	R 80123 is a highly selective inhibitor of phosphodiesterase,is the Z-isomer of R 79595		Others
T15186	(E)-4-Hydroxytamoxifen		Others
	(E)-4-Hydroxytamoxifen is a less active isomer of (Z)-4-hydroxytamoxifen and also is an estrogen receptor modulator.		Others
T35291	Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene
	Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene is the fluorine analog of Methyl eugenol (ME), the attractant of the oriental fruit fly B. dorsalis.The E-isomer is twice as active as the Z-isomer Z-1,2-Dimethoxy-4-(3-fluo...
T74028	(Z)-2-Octenoic acid
	Z-2-Octenoic acid, the Z-isomer of 2-Octenoic acid, is also known as trans-2-Octenoic acid and serves as a metabolite in Mucor species.
T37099	(Z)-4EGI-1
	(Z)-4EGI-1, the Z-isomer of 4EGI-1, serves as an inhibitor of both the eIF4E/eIF4G interaction and translation initiation. It effectively binds to eIF4E, exhibiting an IC50 of 43.5 μM and a Kd value of 8.74 μM. Notably, ...
T83878	Z-CITCO
	Z-CITCO acts as an agonist for the constitutive androstane receptor (CAR; with an EC50 of 3.9 µM in human receptor reporter assays) and is the cis isomer of the CAR agonist CITCO.
T3645	Endoxifen E-isomer hydrochloride	E-Endoxifen hydrochloride	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride) , a tamoxifen metabolite, is effective specific Estrogen Response Modifier (SERM).		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T37213	5-trans Latanoprost
	Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been chan...
T35854	9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
	9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a r...
T37214	5-trans Latanoprost (free acid)
	Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endog...
T36608	(±)8-HEPE
	(±)8-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 8(S)-HEPE and 8(R)-HEPE. The ability of (±)8-HEPE to induce hatching of E. modestus and B. balanoides eggs is probably due to the pres...