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Search Result

Search Results for " sgk "

Targets

SGK SGK

14

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6635 EMD638683 SGK
EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).
T9977 SGK1-IN-4 SGK
SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.
T2622 GSK 650394 GSK650394 SGK , Influenza Virus
GSK 650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor.
T12890 SGK1-IN-1 Others
SGK1-IN-1 is a highly active and selective SGK-1 inhibitor(IC50 of 1 nM).
T12891 SGK1-IN-2 Others
SGK1-IN-2 (14h) is a selective inhibitor of SGK1 (serum and glucocorticoid regulated kinase 1)(with an IC50 of 5 nM at 10 μM ATP concentration).
T13847 PROTAC SGK3 degrader-1 SGK3-PROTAC1 SGK
PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, which induces degradation of endogenous SGK3.PROTAC SGK3 degrader-1 inhibits GDC0941-induced proliferation of can...
T19913 CKI-7 CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl ROCK , SGK , Casein Kinase , CDK , S6 Kinase
CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
T63741 SGK1-IN-3
SGK1-IN-3 is a potent, orally active SGK1 inhibitor. Among them, the serine/threonine kinase SGK1, an activator of the β-linked protein pathway and a powerful stimulator of cartilage degradation, has been found to be upr...
T71947 SGK1 inhibitor
SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphor...
T73247 PIM1-IN-4 Pim
PIM1-IN-4 (Compound 8) is a potent PIM1 inhibitor with significant inhibitory activity against five additional enzymes: SGK-1, PKA, CaMK-1, GSK3β, and MSK1, rendering it a potentially useful agent for cancer research [1]...
T10829 CKI-7 free base CKI-7 Casein Kinase
CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
T10275 AKT-IN-3 Akt
AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kin...
T2356 Ro-3306 Apoptosis , ERK , SGK , PKA , CDK , PKC
RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for CDK1 is >15-fold higher than a diverse panel of human kinases.
T14779 BRD7389 SGK , FLT , Pim , CDK , S6 Kinase , DAPK
BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.

Recombinant Proteins

Species：
Human (2)
Expression System：
Baculovirus-Insect Cells (2)
Tag：
His,GST (2)
Cat No. Product Name Species Expression System
TMPY-04466 STK40 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
STK40 is localized to both the cytoplasm and the nucleus. It is ubiquitously expressed. Mechanistically, Stk40 interacts with Rcn2, which also activates Erk1/2 to induce ExEn specification in mouse ESCs. Stk40 is able to...
TMPY-04561 SGK3 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein that belongs to the protein kinase ...
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