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Results for "

Photosensitizer-1

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    21
    TargetMol | Inhibitors_Agonists
  • Dye Reagents
    6
    TargetMol | Dye_Reagents
  • Natural Products
    1
    TargetMol | Natural_Products
Photosensitizer-1
T753521886-13-1
Photosensitizer-1 (Compound CLB-13) is a photosensitizer [1] .
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2-4 weeks
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Type-I/-II Photosensitizer-1
T205475
Type-I -II Photosensitizer-1 (compound 8b) is a photosensitizer with anticancer properties. It exhibits significant phototoxicity against A549 and 4T1 tumor cells. Under laser irradiation, Type-I -II Photosensitizer-1 demonstrates strong oxygen-independent antitumor activity with an IC50 ranging from 1.50 to 1.76 μM.
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Antimicrobial photosensitizer-1
T743922933179-62-3
Antimicrobial Photosensitizer-1 demonstrates significant potential as an effective agent for treating infections caused by pathogenic microorganisms, with notable antimicrobial efficacy observed in S. aureus-infected mouse wound models [1].
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8-10 weeks
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Photosensitizer-1 hydrochloride
T753532771189-66-1
Photosensitizer-1 (Compound CLB-13) hydrochloride is a photosensitizer [1].
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2-4 weeks
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Antitumor photosensitizer-1
T829982344751-89-7
Antitumor Photosensitizer-1 (Compound 8) is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity, positioning it as a promising new candidate for photodynamic therapy research [1].
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8-10 weeks
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LTB
Lon-TK-BMS-1
T203434
LTB is a prodrug formed through the conjugation of the glycolysis inhibitor (Lonidamine) and the PD1 PDL1 blocker (BMS-1) via a thioketal bond. LTB can encapsulate the photosensitizer Chlorin e6 (Ce6), constructing a co-delivery photodynamic nanoplatfform through self-assembly (LTB-6 NPs).
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TBC-1
T2046572522115-48-4
TBC-1 is a chlorophyll-a derivative that acts as a photosensitizer for photodynamic therapy (PDT). It efficiently generates type I ROS and targets the endoplasmic reticulum. TBC-1 demonstrates in vitro biocompatibility and PDT effectiveness under both normoxic and hypoxic conditions.
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10-14 weeks
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PSDalpha
T74335
PSDalpha, an ERα degrader consisting of a photosensitizer (PS), triphenylamine benzothiadiazole (TB), and 17β-estradiol connected via an acetylene bond, demonstrates superior anti-proliferative effects on MCF-7 cells. Its peak absorption wavelength in the visible region is 465 nm [1].
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Antitumor photosensitizer-3
T74601
Antitumor Photosensitizer-3 (Compound I), a chlorin derivative, effectively induces apoptosis and necrosis in tumor cells upon exposure to 650 nm laser irradiation. This compound demonstrates reduced skin phototoxicity compared to the positive reference m-THPC in vivo [1].
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Benz-AP
T746292416220-53-4
Benz-AP, a potent photosensitizer, generates singlet oxygen inversely related to Human carboxylesterase 2 (hCES2) activity, showcasing enhanced photocytotoxicity in cancer cells within low hCES2 environments. Moreover, upon Two-photon excitation (TPE), Benz-AP induces the production of reactive oxygen species (ROS), effectively killing cancer cells and tumor spheroids [1].
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ICy-OH
T749222863682-80-6
ICy-OH, a iodinated photosensitizer, serves as a potent anticancer agent, capable of deep tissue imaging (λ ex =640 nm, λ em =690-740 nm) and selectively triggering cell death in pancreatic cancer cells through the cell pyroptosis pathway [1].
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Mal-Pc
T750002670367-74-3
Mal-Pc, a phthalocyanine-based molecular photosensitizer featuring maleimides, interacts with GSH to diminish its levels and decrease aggregation, enhancing the ROS (Reactive Oxygen Species)-dependent efficacy of photodynamic therapy (PDT) in targeting cancer cells [1].
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8-10 weeks
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Vitamin K5
T7531783-70-5
Vitamin K5 (Synkamin), a photosensitizer and antimicrobial agent, serves as a specific PKM2 inhibitor, demonstrating IC 50 values of 28, 191, and 120 μM against PKM2, PKM1, and PKL, respectively. It induces apoptosis in colon 26 cells and is utilized in infection and cancer research. Additionally, Vitamin K5 finds application as a preservative in pharmaceuticals, foods, and beverages [1] [2] [3].
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TSPP tetrasodium
T7844239050-26-5
TSPP tetrasodium, a photosensitizer, has demonstrated significant efficacy in the in vivo regression of cancer and microbial infections (Ex: 413 nm, Em: 640 nm) [1][2].
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    Antibacterial agent 140 chloride
    T78903
    Antibacterial agent 140 chloride, a first-of-its-kind Ru-based AIEgen photosensitizer, shows promise in detecting and treating Gram-positive bacteria (G+). It effectively discriminates against and exterminates G+ by interacting with lipoteichoic acids (LTA), displaying robust antibacterial activity under light irradiation [1].
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    Antitumor photosensitizer-4
    T79711
    Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. This photosensitizer (PS) induces apoptosis and reactive oxygen species (ROS) production, while demonstrating significant phototoxicity against both HepG2 and B16-F10 cells [1].
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    Purpurin 18 methyl ester
    T8134651744-55-9
    Purpurin 18 methyl ester, a derivative of chlorophyll-a, serves as a photosensitizer for photodynamic therapy (PDT), exhibiting the ability to induce cancer cell apoptosis [1].
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    Photosensitizer-2
    T814832138330-43-3
    Photosensitizer-2 (compound 1), an organic D-π-A sensitizer, exhibits antitumor properties and potent phototoxicity due to an acrylic acid moiety. It demonstrates significant activity against HeLa cells, with IC 50 values of 20.9 ± 4.5 μM (dark) and 0.046 ± 0.012 μM (irradiation) [1].
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    8-10 weeks
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    Antitumor photosensitizer-2
    T829972344751-92-2
    Compound 11, also known as Antitumor Photosensitizer-2, is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity, representing a promising candidate for photodynamic therapy research [1].
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    8-10 weeks
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    Antifungal agent 87
    T85680692730-21-5
    Antifungal agent 87(10) is a highly potent PDT antimycotic photosensitizer (PDT-IC₅₀ = 1 nM for T. rubrum) [1].
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    10-14 weeks
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    Hexyl 5-aminolevulinate
    HAL
    T86573140898-97-1
    Hexyl 5-aminolevulinate (HAL), a highly lipophilic photosensitizer, enhances photodynamic therapy (PDT) efficiency [1]. This compound is utilized in research on photodynamic therapy (PDT).
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    2-4 weeks
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