mest — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4118	SB 271046 hydrochloride	SB 271046A	5-HT Receptor
	SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and ...		5-HT Receptor
T1579	Mestranol	Devocin,Norquen,Menophase	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Mestranol (Devocin), a semisynthetic estrogen, is used as an estrogen receptor agonist and must be demethylated to be biologically active.		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T1587	Exemestane	EXE,FCE 24304,PNU155971	Aromatase
	Exemestane (EXE) is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.		Aromatase
T12678	(Rac)-Telmesteine	3-(Ethoxycarbonyl)thiazolidine-4-carboxylic acid,3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid,3,4-Thiazolidinedicarboxylic Acid 3-Ethyl Ester	Protease
	(Rac)-Telmesteine (3,4-Thiazolidinedicarboxylic Acid 3-Ethyl Ester) is an inhibitor of protease and is thus a suitable enzyme stabilizer.		Protease
T71708	Minamestane		Aromatase
	Minamestane is a novel irreversible aromatase inhibitor.Minamestane induces time-dependent inhibition of human placental aromatase with a half-life of 4 minutes and a K of 59 nM.Minamestane has antitumor activity.		Aromatase
TQ0295	Coumestrol		Estrogen Receptor/ERR
	Coumestrol that existed in soybean products suppresses the proliferation of ES2 cells (IC50: 50 μM). It exhibits activities against neurological disorders, cancers and autoimmune diseases.		Estrogen Receptor/ERR
T12564	Prudomestin	3,5,7-Trihydroxy-4',8-dimethoxyflavone	Xanthine Oxidase
	Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) is a natural product isolated from the heartwood of Prunus domestica, with xanthine oxidase (XO) inhibitory activity with IC50 of 6 µM.		Xanthine Oxidase
T1536	Promestriene	3-propyl ethyl,17B-methyl estradiol,Promestriano	Estrogen/progestogen Receptor
	Promestriene (3-propyl ethyl) (INN) is a synthetic estrogen and glucocorticoid used topically in a 1% cream formulation. It is described as a tropic agent and antiseborrheic.		Estrogen/progestogen Receptor
T35772	Emestrin
	Emestrin is a mycotoxin originally isolated from E. striata that has antimicrobial, immunomodulatory, and cytotoxic activities.1,2,3,4,5 It is active against the fungi C. albicans and C. neoformans, as well as the bacter...
T28942	Telomestatin	SOT 095,GM95,(R)-Telomestatin,GM 95,GM-95
	Telomestatin is an inhibitor of the telomerase, it induces the formation of basket-type G-quadruplex (G4) structures from hybrid-type G-quadruplexes in the telomeric region.
T31485	Dimestrol
	Dimestrol can induce DNA damage.
T29886	Almestrone	BA-38372,BA 38372,Ciba-38372,BA38372,Ciba 38372
	Almestrone (developmental code names Ba 38372, Ciba 38372), also known as 7α-methylestrone, is a synthetic, steroidal estrogen which was synthesized in 1967 but was never marketed. It is used as a precursor in the synthe...
T68775	Etamestrol
	Etamestrol is a synthetic, steroidal estrogen described as an ovulation inhibitor or hormonal contraceptive
T33032	Lynestrenol mixture with mestranol
	Lynestrenol mixture with mestranol is a bioactive chemical.
T68720	Plomestane
	Plomestane is a selective inhibitor of aromatization in human breast tissue and may provide a mechanism for controlling estrogen responsive processes.
T24012	Domesticine, (-)-	L-Domesticine
	Domesticine, (-)- is an antagonist of alpha-1D-adrenoceptor.
T20956	Telmesteine
	Telmesteine is a mucolitic drug.
TN5883	4'-O-Methylcoumestrol	9-O-Methylcoumestrol
	4'-O-Methylcoumestrol is a natural product from Glycyrrhiza pallidiflora Maxim.
T82220	Hedysarimcoumestan B
	Hedysarumcoumestan B, a natural product, is isolated from the roots of Hedysarum multijugum [1].
T35676	17β-hydroxy Exemestane
	17β-hydroxy Exemestane is the primary active metabolite of exemestane . It is formed by metabolism of exemestane by the cytochrome P450 (CYP) isoforms CYP1A and CYP4A11. 17β-hydroxy Exemestane is an aromatase inhibitor (...