T4558 |
Trioxsalen
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Trimethylpsoralen,Trioxysalen,三甲沙林,Trisoralen |
DNA Alkylator/Crosslinker
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DHFR
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Trioxsalen 是一种呋喃香豆素和补骨脂素衍生物,与 UV-A 一起用于光疗治疗白癜风和手部湿疹。它是一种光化学 DNA 交联剂,可用于激光激活定位的基因组链间交联可视化。 |
T2410 |
Nedaplatin
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奈达铂,NSC 375101D |
DNA/RNA Synthesis
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Nedaplatin 是顺铂的衍生物,是肿瘤集落形成单位的 DNA 损伤剂,IC50为94 μM。 |
T0974 |
Novobiocin Sodium
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新生霉素钠,Albamycin,Cathomycin,Albamycinsodium |
Autophagy
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ABC
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Antibiotic
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Potassium Channel
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DNA gyrase
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Topoisomerase
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Antibacterial
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Novobiocin sodium 是源自 Streptomyces niveus 的抗生素。 它的化学结构类似于香豆素。Novobiocin 与 DNA 促旋酶结合并阻断三磷酸腺苷活性。 |
T34628 |
SG3199
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SG 3199,SG-3199 |
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SG3199 is a PBD dimer which binds in the minor groove of DNA, and forms covalent DNA interstrand cross-links in naked li... |
T72817 |
Colibactin 742
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Colibactin 742 是一种稳定的大肠杆菌素衍生物,可诱导DNA 链间交联、激活 Fanconi Anemia DNA 修复途径和 G2/M 期阻滞。 |
T68675 |
Porfiromycin
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Porfiromycin is a n N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Strepto... |
T68942 |
Caricotamide
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Caricotamide is a synthetic co-substrate that activates the human endogenous enzyme NRH:quinone oxidoreductase 2 (NQO2) ... |