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825658-63-7

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
RTI-7470-44
T62706825658-63-7
RTI-7470-44 is a potent and selective human trace amine-associated receptor 1 (hTAAR1) antagonist (IC50: 8.4 nM) that crosses the blood-brain barrier. RTI-7470-44 increases the spontaneous firing rate of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain in mice. RTI-7470-44 can be used to study schizophrenia, drug addiction and Parkinson's disease (PD).
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6-8 weeks
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