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Results for "
2829282-00-8
" in TargetMol Product Catalog- Inhibitors & Agonists1
ly367385 hydrochloride
T603552829282-00-8
LY367385 hydrochloride is a potent and selective mGluR1a antagonist with an IC50 value of 8.8 μM for inhibiting quisqualate-induced phosphoinositide (PI) hydrolysis, showing significantly higher selectivity compared to its >100 μM IC50 value for mGlu5a. This compound exhibits neuroprotective, anticonvulsant, and antiepileptic effects [1] [2].
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(±)-LY367385
T39406198419-90-8
(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 exhibits a high inhibitory activity against quisqualate-induced phosphoinositide (PI) hydrolysis, with an IC50 value of 8.8 μM. In contrast, its inhibitory activity against mGlu5a is greater than 100 μM.
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T15818198419-91-9
LY367385 is a highly effective and selective mGluR1a antagonist. LY367385 has neuroprotective, anticonvulsant, and antiepileptic effects. Compared with > 100 μM for mGlu5a, LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis.
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