21-amino

Endothelin-2 (49-69), human (Human endothelin-2), is a 21-amino-acid vasoactive peptide that binds to G-protein-coupled receptors ET-RA and ET-RB.

gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate possesses higher affinity than NKA for central NK-2 receptors; it shows lower affinity for NK-1 receptors, however, it potently stimulates salivary secretion, which is mediated by NK-1 receptor activation.

Histone H3 (21-44), derived from the 21-44 amino acid sequence of histone H3, is commonly used as a substrate in protein arginine methyltransferase assays to analyze methylation activity.

Histone H3 (1-21) is a truncated form of the Histone H3 protein consisting of amino acids 1 to 21. It serves as a common substrate for methyltransferase assays targeting Histone 3 at lysine 4 and lysine 9, as well as for acetyltransferase assays targeting Histone 3 at lysine 9 and lysine 14.

2-Amino-4-(ethylthio)butanoic acid is a valuable organic compound for life sciences research [Catalog Number: T66823, CAS Number: 67-21-0].

Forigerimod (IPP-201101), a potent CD4 T-cell modulator, is a 21-amino-acid fragment of the U1 small nuclear ribonucleoprotein 70 kDa, phosphorylated at Ser140, known for its ability to inhibit autophagy effectively. It has applications in researching autoimmune disorders, including systemic lupus erythematosus (SLE) [1] [2] [3] [4].

Forigerimod TFA (IPP-201101 TFA), a CD4 T-cell modulator, is a phosphorylated 21-amino-acid fragment derived from U1 small nuclear ribonucleoprotein 70 kDa, specifically at Ser140. It notably inhibits autophagy and is utilized in researching autoimmune disorders, including systemic lupus erythematosus (SLE) [1] [2] [3] [4].

Catestatin TFA, a 21-amino acid residue peptide, exhibits both cationic and hydrophobic properties. This endogenous peptide plays a crucial role in regulating cardiac function and blood pressure. It functions as a non-competitive nicotinic antagonist by interacting with nicotinic acetylcholine receptors (nAChRs) to inhibit catecholamine release.

LL-37 GKE acetate, a peptide with 21 amino acids and the active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production, is less toxic than LL-37 for hemolysis and apoptosis in human cultured smooth muscle cells, and possesses antimicrobial activity and therapeutic potential for sepsis.

Mad1 (6-21) TFA, a fragment encompassing amino acids 6 to 21 of the Mad1 protein, exhibits a strong affinity for the PAH2 domain of mammalian Sin3A with a dissociation constant (Kd) of approximately 29 nM [1].

ELAAWCRWGFLLALLPPGIAG TFA (P5), a 21-amino-acid peptide (aa 5-25) originating from the rat HER2/neu protein, has been shown to elicit cytotoxic T lymphocyte (CTL) responses in mice with HER2-positive tumors [1].

ELAAWCRWGFLLALLPPGIAG (P5), a 21-amino acid peptide (aa 5-25) derivative of the rat HER2/neu protein, has been shown to elicit cytotoxic T lymphocyte (CTL) responses in mice with HER2-positive tumors [1].

BNP (1-21), Pro (Human) is a 21-amino acid peptide and a form of B-Type Natriuretic Peptide (BNP), a cardiac natriuretic hormone that coexists with the homologous atrial natriuretic peptide in the heart's dual natriuretic peptide system. BNP plays a critical role in heart organogenesis and the transition to extrauterine life [1] [2] [3].

Acetyl-Heme-Binding Protein 1 (1-21) (human) is a peptide containing the first 21 amino acids of hemopexin Acetyl-Heme-Binding Protein 1, playing a role in heme binding, heme metabolism, and hemoglobin release [1].

Spike Binding Peptide 1 (SBP1), representing amino acids 21-43 of angiotensin-converting enzyme 2 (ACE2), has been utilized in a novel approach involving lipid nanoparticles (LNPs) encapsulated with oseltamivir phosphate and conjugated to SBP1. This formulation aims to investigate the possibility of achieving a controlled, long-term in vivo release of oseltamivir phosphate. Furthermore, a 2% concentration of SBP1 immobilized on crosslinked networks composed of hydroxy acrylate and ethylxanthate ethyl acrylate has demonstrated enhanced in vitro efficiency in capturing the spike glycoprotein of severe acute respiratory coronavirus 2 (SARS-CoV-2), also referred to as the surface glycoprotein.

Selenocysteine ​​is considered to be the 21st amino acid in ribosome-mediated protein synthesis, and its specific incorporation is directed by the UGA codon.

Fibronectin Adhesion-promoting Peptide acetate (Heparin Binding Peptide acetate) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.

Endothelin-3 (Rat, Human) (TFA) is a 21-amino acid vasoactive peptide of endothelial origin. It acts as an agonist for the endothelin receptor type B (EDNRB), is crucial for neural crest cell development, and promotes the migration of endothelial cell-derived cells (ENCCs).

Endothelin-3 (human, mouse, rabbit, rat) is a cyclic 21-amino acid peptide, acting as an endogenous neuropeptide and potent vasoconstrictor.

CEF3 (SIIPSGPLK) is a peptide representing amino acids 13-21 of the M1 protein in the influenza A virus. The M1 protein is a versatile component of the influenza A virus, carrying out crucial structural and functional tasks throughout the virus's life cycle.

Pep-1 (uncapped), which has 21 amino acid residues, is a known carrier peptide that delivers full-length native proteins in vitro and in vivo.

Endothelin-2 (49-69), human (TFA), is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB receptors.

Microcin J25 (MccJ25) is a cyclopeptide antibiotic made up of 21 unmodified amino acid residues. It effectively inhibits the DNA-dependent RNA polymerase (RNAP) of Gram-negative bacteria and exhibits antibacterial activity.

SA-21 is a polymeric peptide consisting of 21 amino acids (Ac-RLIEDICLPRWGCLWEDD-NH2) capable of binding to the ligand of urokinase-type plasminogen activator, Fab antibody fragments, and small proteins. It is useful for purifying albumin (Ki=1.9 μM).