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136904-69-3

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
2′-Thioadenosine
PD157432
T78634136904-69-3
2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, demonstrating an IC50 value of 45 µM against ErbB-2. It achieves covalent inactivation of ErbB-1 through modification of a cysteine residue within the enzyme's active site [1].
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8-10 weeks
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