10pyrenepc

10-Pyrene-PC is a substrate for all PLA2s with the exception of cPLA2 and PAF-AH. Upon phospholipid hydrolysis, 10-pyrenyldecanoic acid is produced from 10-pyrene-PC. The monomeric 10-pyrenyldecanoic acid exhibits fluorescence (excitation 345 nm, emission 395 nm), allowing quantitation of phospholipase activity.

SM-102 is the only ionizable amino cationic lipid currently clinically approved for RNA therapeutics and can be used to synthesize lipid nanoparticles (LNPs). It shows potential in the development of LNPs for the delivery of mRNA-based vaccines.

Fructooligosaccharides (FOS) are naturally occurring functional oligosaccharides, which are composed of 2 to 10 fructose molecules combined with glucose molecules. They are widely found in natural plants such as bananas, onions, garlic, chicory, and honey. As a typical prebiotic, fructooligosaccharides cannot be digested and absorbed by the human body, but are selectively fermented by beneficial gut bacteria, especially bifidobacteria, to promote gut health, support microbial balance.

o-Phenanthroline monohydrate (1, 10-Phenanthroline monohydrate) is an inhibitor of metallopeptidases, inhibits zinc-dependent hydrolysis of Fa-Gly-Leu-NH2 by B. subtilis neutral protease and B. thermoproteolyticus thermolysin.

Methyl Undecenate (Methyl undec-10-enoate) is a fatty acid methyl ester of 10-undecenoic acid. It has a role as a metabolite. It derives from a 10-undecenoic acid.

Polyoxyl 10 oleyl ether is an emulsifying agent. It is used as vehicle for organic compunds in aqueous solutions.

Butyl cinnamate is an agent of mosquito repellent.

9-Decenoic acid (Dec-9-enoic acid) is a monounsaturated fatty acid with 10 carbon atoms that is used in organic synthesis and biochemical experiments.

Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 µg ml) but not against K. pneumoniae, S. typhimuriu

Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, it acts as an antioxidant. Coenzyme Q2 is a precursor of coenzyme Q10 that has 2, rather than 10, isoprenoid units on the ubiquinone base. It can act as an electron acceptor for bacterial Complex I. In mammalian cells, exogenous coenzyme Q2 prevents the production of reactive oxygen species associated with Complex I activity. Forms of coenzyme Q with shorter isoprenoid chains, including coenzyme Q2, induce p53-dependent apoptosis in human B-cell acute lymphoblastoid leukemia BALL-1 cells.

Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lopez, J.A.V., Nogawa, T., Futamura, Y., et al.Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647J. Antibiot. (Tokyo)72(12)991-995(2019) 2.Ishida, S., Arai, M., Niikawa, H., et al.Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium speciesBiol. Pharm. Bull.34(6)917-920(2011) 3.Kalinovskaya, N.I., Romaneko, L.A., Irisawa, T., et al.Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activityMicrobiol. Res.166(8)654-661(2011) 4.Matsubara, K., Sakuda, S., Tanaka, M., et al.Morphological changes in insect BM-N4 cells induced by nocardamineBiosci. Biotechnol. Biochem.62(10)2049-2051(1998)

2-Amino-6-chloropurine is a precursor in the synthesis of nucleoside analogs with antiviral activity against Epstein-Barr virus (EBV) and human herpes virus 6 (HHV-6).1 1.Qiu, Y.-L., Ksebati, M.B., Ptak, R.G., et al.(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activityJ. Med. Chem.41(1)10-23(1998)

Lipid 10, an ionizable amino lipid, is utilized in the production of Lipid nanoparticles (LNPs).

Ionizable Lipid-1 (compound II-10), with a pKa of 6.16, is an ionizable lipid capable of forming lipid nanoparticles (LNP) with a bilayer structure [1].

16:0-10 Doxyl PC is a reagent used in biochemical reactions.

4-trans,7-cis,10-cis,13-cis,16-cis,19-cis-Docosahexaenoic acid is a reagent used in biochemical reactions.

Cholesteryl 10-undecenoate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

10:0 PS is a reagent used in biochemical reactions.

10:0 PA (1,2-Didecanoyl-sn-glycero-3-phosphate) sodium is an anionic lipid used in the formulation of nanoemulsions to enhance the oral bioavailability of Etoposide.

1,2-Didecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium is a reagent used in biochemical reactions.

Cross-linked dextran G 10 is a weak cation exchanger and hydrophilic gel, suitable for use as a gel filtration medium (spherical proteins separation range: >700 Da; polysaccharides separation range: >700 Da).

Ionizable lipid-1 (compound II-10) is a lipid with an ionizable characteristic (pKa=6.16) that is utilized in the creation of lipid nanoparticles (LNP) with a bilayer structure.

Genevant CL1 monohydrochloride is an ionizable cationic lipid (lipid 10, pKa=6.3) used for the delivery of mRNA lipid nanoparticles (LNP) in vaccine applications.

Ethyl cellulose (viscosity 10 cP) is a non-toxic and biodegradable polymer known for its unique capabilities in forming oil gels, delivering active ingredients, and film-forming in the food and pharmaceutical industries. It can serve as a pharmaceutical excipient, such as a coating agent, flavoring agent, and tablet filler.