10-pyrene-pc

10-Pyrene-PC is a substrate for all PLA2s with the exception of cPLA2 and PAF-AH. Upon phospholipid hydrolysis, 10-pyrenyldecanoic acid is produced from 10-pyrene-PC. The monomeric 10-pyrenyldecanoic acid exhibits fluorescence (excitation 345 nm, emission 395 nm), allowing quantitation of phospholipase activity.

SM-102 is the only ionizable amino cationic lipid currently clinically approved for RNA therapeutics and can be used to synthesize lipid nanoparticles (LNPs). It shows potential in the development of LNPs for the delivery of mRNA-based vaccines.

Fructooligosaccharides (FOS) are naturally occurring functional oligosaccharides, which are composed of 2 to 10 fructose molecules combined with glucose molecules. They are widely found in natural plants such as bananas, onions, garlic, chicory, and honey. As a typical prebiotic, fructooligosaccharides cannot be digested and absorbed by the human body, but are selectively fermented by beneficial gut bacteria, especially bifidobacteria, to promote gut health, support microbial balance.

Dibenzofuran possesses multiple biological activities, including inhibition of the aryl hydrocarbon receptor and bovine viral diarrhoea virus.

Sodium caprate (Sodium decanoate) is the sodium salt of caproic acid, a 10-carbon saturated fatty acid. It has an amphiphilic character and can form liquid crystalline phases and micelles in an aqueous solution.

Chitin is a large, structural polysaccharide found in the cell walls of fungi, the exoskeletons of insects, and certain hard structures in fish and invertebrates.

Phosphatidylethanolamines (bovine) are a mixture of phosphatidylethanolamines isolated from bovine brain with different fatty acyl groups at the sn-1 and sn-2 positions.Phosphatidylethanolamines (bovine) are the most abundant phospholipids in prokaryotes and the second most abundant in mammalian, plant and yeast cell membranes. Phosphatidylethanolamines (bovine) are the most abundant phospholipids in prokaryotes and the second most abundant phospholipids in the cell membranes of mammals, plants, and yeast, accounting for about 25% of the total mammalian phospholipids.

N-Phenylurea, with CAS No. 64-10-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-Phenylurea provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

o-Phenanthroline monohydrate (1, 10-Phenanthroline monohydrate) is an inhibitor of metallopeptidases, inhibits zinc-dependent hydrolysis of Fa-Gly-Leu-NH2 by B. subtilis neutral protease and B. thermoproteolyticus thermolysin.

Methyl Undecenate (Methyl undec-10-enoate) is a fatty acid methyl ester of 10-undecenoic acid. It has a role as a metabolite. It derives from a 10-undecenoic acid.

Methyl Nonanoate is an organic compound containing an ester group that is widely used in biochemical experiments and drug synthesis research.

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) is a phospholipid commonly found in cell membranes, with cholesterol compositions ranging from 0 to 60 mol%.

Polyoxyl 10 oleyl ether is an emulsifying agent. It is used as vehicle for organic compunds in aqueous solutions.

Butyl cinnamate is an agent of mosquito repellent.

9-Decenoic acid (Dec-9-enoic acid) is a monounsaturated fatty acid with 10 carbon atoms that is used in organic synthesis and biochemical experiments.

Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 µg/ml) but not against K. pneumoniae, S. typhimuriu

Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, it acts as an antioxidant. Coenzyme Q2 is a precursor of coenzyme Q10 that has 2, rather than 10, isoprenoid units on the ubiquinone base. It can act as an electron acceptor for bacterial Complex I. In mammalian cells, exogenous coenzyme Q2 prevents the production of reactive oxygen species associated with Complex I activity. Forms of coenzyme Q with shorter isoprenoid chains, including coenzyme Q2, induce p53-dependent apoptosis in human B-cell acute lymphoblastoid leukemia BALL-1 cells.

Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lopez, J.A.V., Nogawa, T., Futamura, Y., et al.Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647J. Antibiot. (Tokyo)72(12)991-995(2019) 2.Ishida, S., Arai, M., Niikawa, H., et al.Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium speciesBiol. Pharm. Bull.34(6)917-920(2011) 3.Kalinovskaya, N.I., Romaneko, L.A., Irisawa, T., et al.Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activityMicrobiol. Res.166(8)654-661(2011) 4.Matsubara, K., Sakuda, S., Tanaka, M., et al.Morphological changes in insect BM-N4 cells induced by nocardamineBiosci. Biotechnol. Biochem.62(10)2049-2051(1998)

2-Amino-6-chloropurine is a precursor in the synthesis of nucleoside analogs with antiviral activity against Epstein-Barr virus (EBV) and human herpes virus 6 (HHV-6).1 1.Qiu, Y.-L., Ksebati, M.B., Ptak, R.G., et al.(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activityJ. Med. Chem.41(1)10-23(1998)

Dehydroergosterol (DHE) is a naturally occurring fluorescent sterol analog that is a compound for real-time detection/elaboration of the sterol environment and intracellular sterol transport in organisms. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells.

Concanavalin A is a natural product, a phytoalexin (glycan-binding protein). Concanavalin A has antitumor activity and can also induce acute liver injury.

Genevant CL1 (lipid 10) is an ionisable lipid (pKa=6.3) suitable for preparing lipid nanoparticles (LNP) for delivering nucleic acid payloads and intramuscular vaccines.

cis-10-Heptadecenoic acid is a minor constituent of ruminant fats.

Lipid 10, an ionizable amino lipid, is utilized in the production of Lipid nanoparticles (LNPs).