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α-Conotoxin GI

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α-Conotoxin GI
alpha-conotoxin GI,α-Conotoxin GI
T3532576862-65-2
α-conotoxin GI, a conopeptide isolated from the venom of the cone snail Conus geographus, is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors (nAChR) such as α-conotoxin MI or d-Turbocurarine.
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α-Conotoxin GI acetate
α-Conotoxin GI acetate (76862-65-2 Free base)
T35325L
α-Conotoxin GI acetate is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors (nAChR).
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α-Conotoxin GID
T80165547741-78-6
α-Conotoxin GID is a paralytic peptide neurotoxin that selectively antagonizes nAChR with IC50 values of 5 nM (α7), 3 nM (α3β2), and 150 nM (α4β2). This small, disulfide-rich peptide has potential for chronic pain inhibition. The presence of a C-terminal carboxylate is crucial, as substitution with a C-terminal carboxamide results in loss of activity against α4β2 nAChR. Derived from species of the genus Conus [1] [2] [3].
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α-Conotoxin GIC
T80478757236-92-3
α-Conotoxin GIC is a selective and potent antagonist of the α3β2 nicotinic acetylcholine receptor, exhibiting an inhibition constant (IC50) of 1.1 nM [1].
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