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TargetMol | Tags Bioluminescence imaging

Luciferase

Luciferase is a key enzyme used in bioluminescent imaging, which can catalyze the oxidation reaction of the substrate luciferin to generate light signals. Through genetic engineering technology, luciferase is introduced into cells or organisms to monitor biological processes such as gene expression, protein interaction and tumor growth in real time. Its high sensitivity and low background signal make it an important tool for in vivo imaging, drug screening and disease research.

D-Luciferin potassium
T4139115144-35-9
D-Luciferin potassium (D-Luciferin K Salt) is a popular bioluminescent substrate of luciferase in the presence of ATP.
  • $41
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TargetMol | Inhibitor Hot
D-Luciferin Sodium
T19743103404-75-7
D-Luciferin Sodium is a heterocyclic light-emitting compound and natural ligand for luciferase used to detect cell activity. The salt form of luciferin dissolves in water or other typical buffers.
  • $30
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CycLuc1
T150301247879-16-8
CycLuc1, a brain-penetrant luciferase substrate, may be a superior BLI substrate compared to D-luciferin for monitoring tumor growth in intracranial GBM (glioblastoma) xenografts.
  • $40
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Diphenylterazine
T18978344940-63-2
Diphenylterazine (DTZ) is a bioluminescent agent. It produces very little background of its own, giving it an excellent signal-to-noise ratio.
  • $30
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Gly-Pro-AMC hydrobromide
T78410115035-46-6
Gly-Pro-AMC hydrobromide (Gly-Pro-AMC HCl) is a specific fluorescent dye used in cytofluorescence assays to detect Dipeptidyl peptidase IV (DPP-IV) activity.
  • $68
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pyCTZ
T395712125486-34-0
PyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, functions as an ATP-independent substrate for LumiLuc luciferase, producing intense blue bioluminescence when combined with luciferases. This compound is also applicable in aequorin-based calcium sensing.
  • $1,520
6-8 weeks
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DPP-8/9 probe-1
T863043020859-80-4
DPP-8/9 probe-1 (compound 20) is a fluorescent probe designed to specifically target and label Dipeptidyl Peptidase DPP8/9, allowing for its visualization through fluorescence microscopy in vitro when active. This compound incorporates a nitrobenzoxadiazole (NBD) tag, demonstrating a high affinity and selectivity for DPP8/9, with significant preference over other S9 family enzymes, evidenced by IC 50 values of 210 nM and 15 nM, respectively. [9] [1]
  • $1,670
8-10 weeks
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N-(NBD-Aminolauroyl)safingol
T86947474943-07-2
N-(NBD-Aminolauroyl)safingol is characterized by its role as a fluorescent group.
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N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium
T86946185503-88-2
N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium (1,8-EDNAS sodium) serves as a multifunctional dye with diverse applications in both scientific and industrial fields. Within biological experiments, this dye enables researchers to investigate cell structures, track biomolecules, assess cell functions, identify various cell types, detect biomolecules, examine tissue pathology, and monitor microorganisms. It is employed extensively in fundamental scientific research and a broad array of clinical diagnostics. Beyond biological uses, 1,8-EDNAS sodium is also integral in traditional sectors like textile dyeing and in innovative areas including functional textile processing, food pigments, and dye-sensitized solar cells.
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BZiPAR
T85930254451-46-2
BZiPAR is a fluorescent probe and a substrate of trypsin that becomes fluorescent after cleavage by the protease [1].
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