alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.

1. gamma-Mangostin (Normangostin) as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells. 3. Gamma-Mangostin could serve as a micronutrient for colon cancer prevention and is a potential lead compound for the development of anti-colon cancer agents. 4. Gamma-Mangostin may acts as an antihypertensive agent , by causing vasorelaxation which is mediated via the NO-cGMP pathway.

Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1. The IC50s of Gambogic Acid for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 uM, respectively.

Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors [resulting in an anticancer effect], and may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.

Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.

8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has multifunctional activities against Alzheimer's disease (AD) and could be promising compounds for the therapy of AD.

1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal . 3. 5,7-Dihydroxychromone induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.

Morellic acid has anti-cancer activity, it strongly inhibited the migration of HUVEC at a low concentration of 0.5 μM in HUVEC cell migration assay in vitro. Morellic acid also has antiangiogenic activity.

Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers.

Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 activation with IC50 values of 3.2 micr

(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyase, which catalyzes the conversion of citrate and coenzyme A to oxaloacetate and acetyl coenzyme A (acetyl-CoA), primary building blocks of fatty acid and cholesterol synthesis.

Fuscaxanthone C is a natural product from Garcinia mangostana.

Gartanin is an androgen receptor degradation enhancer, it is also a potential neuroprotective agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK SIRT1 PGC-1α±signaling pathways.

2,4'-Dihydroxybenzophenone can effectively protect C57BL/6J mice from APAP-induced hepatotoxicity. Its mechanisms might be associated with its Antioxidant activity.

3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial activity with IC50 values in the rang

Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg mL. Beta-mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg mL. Beta-mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).

1,5,6-Trihydroxy-3,7-dimethoxyxanthone shows cytotoxic activity against the KB cell line.

GB 2a shows antioxidant and anti-inflammatory effects, it can prevent the carrageenan-induced paw oedema. GB 2a biflavonoid can promote inhibition on tyrosinase activity and reduced melanin biosynthesis in B16F10 cells, which suggests great potential for

Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines.

Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer.

3-(3-Hydroxy-3-methylbutanyl)-2,4,6-trihydroxybenzophenone is a natural product for research related to life sciences. The catalog number is TN2862 and the CAS number is 1432062-53-7.

Beta-Tocotrienol to serve as a new anticancer agent for treating human lung and brain cancers. It inhibits the growth of both A549 (GI50=1.38±0.334μM) and U87MG (GI50=2.53±0.604μM) cells at rather low concentrations.

1-Isomangostin has cytotoxic and anticomplementary activities.

Mangostanol is an acetylcholinesterase (AChE) selective inhibitor.Mangostanol has anti-cancer activity, it shows significant activities against the CEM-SS cell line, with IC50 values of 9.6 microg/ml.

Subelliptenone G is a natural product from Garcinia hanburyi Hook.f.

2,3',4,6-Tetrahydroxybenzophenone possesses significant antioxidant activity.

6-Prenylapigenin(4',5,7-Trihydroxy-6-prenylflavone) shows potent inhibitory activity on melanin formation, it may be potential sources for skin whitening agents. It also shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarci

8-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane is a natural product for research related to life sciences. The catalog number is TN3272 and the CAS number is 63565-07-1.

O-Demethylforbexanthone is a natural product for research related to life sciences. The catalog number is TN4686 and the CAS number is 92609-77-3.

1,6,7-Trihydroxyxanthone has anti-cancer activity ,at least in part, through the activation of miR-218 and suppression of Bmi-1 expression; can suppress cell growth and induce apoptosis in liver cancer cells.

7-Prenyljacareubin shows moderate cytotoxic activity against HL-60, SMMC-7721, A549, MCF-7, and SW480 cell lines.

Isomorellic acid is a cytotoxic caged xanthone [fungus deriving].

6-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane is a natural product for research related to life sciences. The catalog number is TN3154 and the CAS number is 86606-14-6.

Nigrolineaxanthone V is a natural product of Garcinia, Clusiaceae. The catalog number is TN4657 and the CAS number is 864516-31-4. Nigrolineaxanthone V can be used as a reference standard.

Garcinexanthone A is a natural product for research related to life sciences. The catalog number is TN4111 and the CAS number is 1107620-67-6.

2,5-Dihydroxyxanthone is a natural product for research related to life sciences. The catalog number is TN2731 and the CAS number is 35040-32-5.

Isogarciniaxanthone E is a natural product from Garcinia mangostana.

Latisxanthone C shows inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells, it may be a valuable antitumor promoter.

1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone, a natural product used in life sciences research, is cataloged under TN2494 with CAS number 160623-47-2.

1,7-Dihydroxy-3-methoxy-2-prenylxanthone is a natural product for research related to life sciences. The catalog number is TN2518 and the CAS number is 77741-58-3.

2,2',3'-Trihydroxy-4,6-dimethoxybenzophenone is a natural product for research related to life sciences. The catalog number is TN2677 and the CAS number is 219861-73-1.

Parvifolixanthone A is a natural product from Garcinia parvifolia.

Parvifolixanthone B is a natural product from Garcinia parvifolia.

1,2,5-Trihydroxyxanthone has antioxidative properties.

Paucinervin A has inhibitory effect against HeLa cell growth, with the IC50 value of 29.5 microM.

3-Isomangostin hydrate is a natural product for research related to life sciences. The catalog number is TN2954 and the CAS number is 26063-96-7.

3-Isomangostin hydrate formate is a natural product for research related to life sciences. The catalog number is TN2955 and the CAS number is 925705-36-8.

3-Prenyl-2,4,6-trihydroxybenzophenone is a natural product for research related to life sciences. The catalog number is TN2983 and the CAS number is 93796-20-4.

Isonormangostin is a natural product of Garcinia, Clusiaceae. The catalog number is TN4316 and the CAS number is 15404-80-5. Isonormangostin can be used as a reference standard.

1,5,6-Trihydroxyxanthone exhibits antibacterial activity against Gram-positive bacteria.