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Isodon

  • Oridonin
    T279028957-04-2
    Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2.
    • $45
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  • Glaucocalyxin A
    T4S049879498-31-0
    1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expression of X-linked inhibitor of apoptosis protein. 3. Glaucocalyxin A inhibits Akt phosphorylation, suppresses proliferation, and promotes apoptosis in a dose-dependent manner, but not in normal glial cells. 4. Glaucocalyxin A inhibits collagen-stimulated tyrosine phosphorylation of Syk, LAT, and phospholipase Cγ2, the signaling events in collagen receptor GPⅥ pathway. 5. Glaucocalyxin A could potentially be developed as an antiplatelet and antithrombotic agent, can inhibit platelet p-selectin secretion and integrin activation by convulxin, is a GPVI selective ligand.
    • $100
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  • Lasiodonin
    TN441938602-52-7
    Lasiodonin is a natural product isolated from the leaves of Isodon parvifolius.
    • $179
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  • Lophanthoidin F
    TN4453120462-46-6
    Lophanthoidin F is a kind of natural product derived from the herbs of Rabdosia lophanthoides.
    • $179
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  • Lophanthoidin B
    TN4451120462-42-2
    Lophanthoidin B is a natural product isolated from the herbs of Rabdosia lophanthoides.
    • $195
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  • Bulleyanin
    TN3548123043-54-9
    Bulleyanin shows strong inhibition of mouse ehrlich ascites carcinoma (ECA), mouse sarcoma S-180, and mouse liver ascites.
    • $829
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  • Sculponeatin B
    TN497085287-60-1
    Sculponeatin A is a natural product from Rabdosia amethystoides.
    • $898
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  • Kamebanin
    TN437539388-57-3
    Kamebanin, a natural diterpenoid, has antibacterial activity. It also shows efficient cytotoxic activity against HeLa and HL-60 cells.
    • $786
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  • Maoyerabdosin
    TN449590468-72-7
    Maoyerabdosin is a kind of natural product derived from the herbs of Isodon.
    • $195
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  • Sculponeatin N
    TN49721169805-98-4
    Sculponeatin N may have protective effects on the lipid peroxidation-damaged live cells.
    • $195
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  • Lophanthoidin E
    TN4452120462-45-5
    Lophanthoidin E is a kind of natural product derived from the herbs of Rabdosia lophanthoides.
    • $195
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  • Maoecrystal B
    TN449496850-29-2
    Maoecrystal B is a diterpenoid isolated from the leaves of Isodon eriocalyx var.
    • $745
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  • Trichorabdal A
    TN517385329-59-5
    Trichorabdal A shows a very strong in vitro antibacterial activity against Helicobacter pylori.
    • $829
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  • Rosthornin A
    TN4919125164-55-8
    Rosthornin A is a kind of natural product derived from the herbs of Rabdosia rosthornii.
    • $829
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  • Sculponeatin O
    TN49731169806-00-1
    Sculponeatin O may have protective effects on the lipid peroxidation-damaged live cells.
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    • Epieriocalyxin A
      TN3967191545-24-1
      Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.
      • $216
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    • D-α-Tocopherol acetate
      T101658-95-7
      D-alpha-Tocopherol acetate (Vitamin E Acetate) is hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine.
      • $29
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    • Serrin A
      TN5001845959-98-0
      Serrin A shows weak to moderate cytotoxic activities (IC50<10 uM) against two human cancer cell lines.
      • $1,978
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    • Trichokaurin
      TN517223811-50-9
      Trichokaurin is a natural product of Isodon, Lamiaceae. The catalog number is TN5172 and the CAS number is 23811-50-9. Trichokaurin can be used as a reference standard.
      • $620
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    • Excisanin A
      TN404678536-37-5
      ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatment of breast cancer. Excisanin A shows comparable inhibitory effects on the LPS-induced production of NO and PGE2, and activation of NF-kappaB without affecting cell viability.Excisanin A induces apoptosis in colon cancer cell line SW620 as determined by Annexin V staining, the cleavage of caspase-3 and the proteolytic degradation of poly (ADP-ribose) polymerase (PARP).
      • $980
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    • Sculponeatin K
      TN4971477529-70-7
      Sculponeatin K is a natural product of Isodon, Lamiaceae. The catalog number is TN4971 and the CAS number is 477529-70-7. Sculponeatin K can be used as a reference standard.
      • $250
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    • Sculponeatic acid
      TN49691169806-02-3
      Sculponeatic acid is a natural product of Isodon, Lamiaceae. The catalog number is TN4969 and the CAS number is 1169806-02-3. Sculponeatic acid can be used as a reference standard.
      • $820
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    • 12E,14-Labdadien-20,8beta-olide
      TN26071639257-37-6
      12E,14-Labdadien-20,8beta-olide is a natural product from Isodon yuennanensis.
      • $750
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    • Augustifolin
      TN347066548-01-4
      Augustifolin is a natural product for research related to life sciences. The catalog number is TN3470 and the CAS number is 66548-01-4.
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    • 6-epi-Augustifolin
      TN3164369390-94-3
      6-epi-Augustifolin is a natural product for research related to life sciences. The catalog number is TN3164 and the CAS number is 369390-94-3.
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    • 16-Kaurene-2,6,15-triol
      TN264753452-32-7
      16-Kaurene-2,6,15-triol is a natural product for research related to life sciences. The catalog number is TN2647 and the CAS number is 53452-32-7.
      • $660
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    • Isodonal
      TN428416964-56-0
      Isodonal shows abilities to inhibit K562 cells camparable to that of cisplatin.
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    • Xerophilusin G
      TMA1742304642-94-2
      Xerophilusin G is a natural product of Isodon, Lamiaceae. The catalog number is TMA1742 and the CAS number is 304642-94-2. Xerophilusin G can be used as a reference standard.
      • $790
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    • Liangshanin A
      TN4432122717-54-8
      Liangshanin A is a natural product for research related to life sciences. The catalog number is TN4432 and the CAS number is 122717-54-8.
      • $950
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    • Effusanin E
      TN392276470-15-0
      Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p65 proteins to down-regulate COX-2 expression .
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    • Epinodosin
      TN397320086-60-6
      Epinodosin induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner.Epinodosin has a biphasic, dose-dependent effect on root growth and a strong inhibitory effect on root hair development in Lactuca sativa L. seedlings.
      • $550
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    • Effusanin A
      TN392030220-43-0
      Effusanin A has antibacterial activity. It exhibits DNA-damaging activity in assay which employed DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) yeast strains. Effusanin A shows inhibitory effects on DU145 cells with IC50 value of 3.16 micro
      • $179
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    • Effusanin B
      TN392176470-16-1
      Effusanin B shows antibacterial activity. It exhibits DNA-damaging activity in assay which employes DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) yeast strains.
      • $550
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    • Excisanin B
      TN404778536-36-4
      Excisanin B shows inhibitory effects on LPS-induced production of nitric oxide in murine macrophage RAW264.7 cells.
      • $710
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    • Rabdoternin F
      TN4891155977-87-0
      Rabdoternin F is a natural product from Rabdosia ternifolia.
      • $660
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    • Carpalasionin
      TN360283150-97-4
      Carpalasionin is a natural product from Rabdosia lasiocarpa.
      • $908
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    • Rabdosin B
      TN489084304-92-7
      Rabdosin B shows cytotoxic activity against three human tumour HepG2, GLC-82 and HL-60 cell lines, it induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner. Rabdosin B at higher concentrations inhibits root growth by affecting
      • $367
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    • Isodocarpin
      TN560410391-08-9
      Isodocarpin is a natural product for research related to life sciences. The catalog number is TN5604 and the CAS number is 10391-08-9.
      • $670
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    • 1,10:4,5-Diepoxy-7(11)-germacren-8-one
      TN247632179-18-3
      1,10:4,5-Diepoxy-7(11)-germacren-8-one is a natural product for research related to life sciences. The catalog number is TN2476 and the CAS number is 32179-18-3.
      • $540
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    • Pedalitin
      TMA256322384-63-0
      Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosmarinate and Pedalitin are mixed-type inhibitors.
      • $1,510
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    • alpha-Tocopherolquinone
      T70507559-04-8
      During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. alpha-Tocopherolquinone (Metarene) is reported to downregulate the respiratory activity of mitochondria. alpha-Tocopherolquinone has also displayed antioxidant activities after it is reduced to tocopherylhydroquinone.
      • $30
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    • Lasiodin
      TN185428957-08-6
      Lasiodin (Lasiokaurin) is a diterpene compound from the plant Camellia sinensis that inhibits the proliferation of NPC cells. Lasiodin has antioxidant, antitumor and antibacterial activities, induces cell cycle length and apoptosis, induces cell migration and invasion, and can be used in the study of nasopharyngeal carcinoma.
      • $147
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    • Kamebakaurin
      TWS197773981-34-7
      1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity. 3. Kamebakaurin has anti-cancer and anti-inflammatory activities through direct inhibition of DNA-binding activity of nuclear factor-kappa B (NF-κB) p50.4. Kamebakaurin has anti-neuroinflammatory activity via inhibition of c-Jun NH -terminal kinase and p38 mitogen-activated protein kinase pathway in activated microglial cells.
      • $100
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    • Glycerol 1-(26-hydroxyhexacosanoate)
      TN2380177602-14-1
      Glycerol 1-(26-hydroxyhexacosanoate) has weak activities antiplasmodial
      • $1,550
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    • Acetylsventenic acid
      TN3344126737-42-6
      Acetylsventenic acid is a natural product from Rabdosia excisa.
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    • Sventenic acid
      TN5081126778-79-8
      Sventenic acid is a natural product of Isodon, Lamiaceae. The catalog number is TN5081 and the CAS number is 126778-79-8. Sventenic acid can be used as a reference standard.
      • $820
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    • Odonicin
      TN469351419-51-3
      Odonicin is a kind of natural product derived from the herbs of Rabdosia longituba.
      • $708
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    • ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide
      TN395459885-89-1
      ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide is a natural product for research related to life sciences. The catalog number is TN3954 and the CAS number is 59885-89-1.
      • $590
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    • DL-alpha-Tocopherylacetate
      TN15907695-91-2
      Dl-alpha-tocopheryl acetate is a dietary supplement.
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    • Nodosin
      TN466110391-09-0
      Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia reperfusion injury in liver transplantation.
      • $116
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