Didymin (Neoponcirin) has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy. Didymin may be a potential therapeutic molecule for the treatment of neurodegenerative disorders associated with oxidative stress.
Clinopodiside A, a triterpenoid saponin isolated from Clinopodium polycephalum, has antitumor activity and induces cytotoxicity through BLK and RasGRP2 signaling-mediated autophagy in T24 bladder cancer cells.