Chelating Agents

trans-1,2-Cyclohexanediaminetetraacetic acid is a commonly used aminopolycarboxylic acid and a potent chelating agent for heavy metal ions.

2',3'-O-Isopropylidene-6-mercaptopurine riboside is a compound with excellent metal complexation activity. It is utilized in the study of mechanisms involving metal complexation.

(S)-p-SCN-Bn-DOTA is a bifunctional chelator (Bifunctional Chelator; BFC), serving as a macrocyclic DOTA derivative for tumor pre-targeting. It is utilized for the conjugation of peptides and radionuclides.

NOTA-bis(tBu)ester (NOTA-bis(t-Butylester)) is a derivative of NOTA and serves as a bifunctional chelator suitable for drug conjugation.

p-NCS-Bz-DOTA-GA is a bifunctional chelating agent.

EDTA disodium salt is a type of chelating agent formed by a central metal ion chelated with four carboxylate groups and two amino groups. This compound is capable of binding and chelating metal ions such as calcium, magnesium, and iron, making it useful across industrial, medical, and research settings. In food and beverages, it serves as a preservative; in pharmaceuticals, it acts as a stabilizer; in water treatment, it functions as a chelating agent; and in biochemical and biomedical research, it is utilized as a reagent. Furthermore, EDTA disodium salt has been studied for potential roles in treating heavy metal poisoning and cardiovascular diseases.

DOTMP is a bifunctional chelating agent designed for the stable attachment of radioactive metals to the carrier component of radiopharmaceuticals.

Dibenzo-24-crown-8-ether serves as a phase-transfer catalyst, facilitating the reduction of H2PtCl6·6H2O and FeCl2·4H2O in a thermal system to synthesize 17 nm monodisperse iron-platinum (FePt) alloy nanoparticles.

Diaza-15-crown-5, a crown ether compound, can extend the lifespan of the M intermediate in BR membranes. By altering the surface charge of the BR membrane, Diaza-15-crown-5 affects the interactions between BR molecules and enhances the overall stability of the membrane, allowing the M state to be sustained longer.

Boric anhydride, 99.98% trace metals basis (Boron trioxide, 99.98% trace metals basis) is a biochemical reagent.

Butyne-DOTA is a bifunctional chelator (Bifunctional Chelator; BFC), serving as a macrocyclic DOTA derivative designed for tumor pre-targeting applications. It is utilized for the conjugation of peptides and radionuclides.

DOTAM-mono-acid is a bifunctional chelator (BFC) and a macrocyclic DOTA derivative designed for tumor pre-targeting applications. It is suitable for conjugation with peptides and radionuclides.

Sodium oxalate, ACS, 99.5% (Ethanedioic acid (sodium), ACS, 99.5%), is a biochemical reagent.

Trehalose C14 is a surfactant.

DOTA-amide is a bifunctional chelator (Bifunctional Chelator; BFC) that serves as a macrocyclic DOTA derivative for tumor pretargeting. It's suitable for conjugation with peptides and radionuclides.

Azido-mono-amide-DOTA is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative designed for tumor pretargeting. It facilitates the conjugation of peptides and radionuclides.

Cucurbituril is a container molecule resembling a hollow pumpkin, featuring two identical openings at each end and a hydrophobic cavity in the middle. Its unique chemical properties enable it to selectively encapsulate guest molecules, such as drugs or catalysts, within its cavity, protecting them from environmental influences. Cucurbituril holds significant potential applications in drug delivery, catalysis, and materials science.

NODAGA-tris(t-Bu ester) (NODAG) is a derivative of NODAGA. It can be utilized for labeling peptides, antibodies, and other molecules, followed by radiolabeling for use in PET imaging.

15-Crown-5 is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Benzo-15-crown-5-ether can serve as a chelating agent for sodium and potassium.

DTPA-tetra (t-Bu ester) is a bifunctional chelator (BFC) and a macrocyclic DPTA derivative used in tumor pre-targeting strategies. It is applicable for the conjugation of peptides and radionuclides.

Azido-mono-amide-DOTA-tris(t-Bu ester) is a biochemical reagent commonly used as a click chemistry reagent.

Benzo-18-crown-6-ether (B18C6) is an organic compound used to create stable microcapsule responsive layers, which can be assembled into bilayer microcapsules. For instance, 18-Crown-6-ether is employed to prepare a responsive layer and then coated with a K+-stabilized G-quadruplex cross-linked hydrogel layer. When Mg2+ ions are present, 18-Crown-6-ether and K+ ions enable dissociation and locking with the G-quadruplex cross-linked layer, allowing for switchable controlled release of the load.

18-Crown-6-ether (18C6; 1,4,7,10,13,16-Hexaoxacyclooctadecane) is an organic compound utilized in forming stable microcapsule responsive layers, which can be further assembled into bilayer microcapsules. For instance, a responsive layer can be prepared using 18-Crown-6-ether and coated with a K+ stabilized G-quadruplex crosslinked hydrogel layer. In the presence of Mg2+ ions, 18-Crown-6-ether and K+ ions can respectively dissociate and lock with the G-quadruplex crosslinked layer, achieving switchable controlled release of the payload.