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Enzyme substrate dyes Enzyme substrate dyesProtease substrates
Protease substrate dyes are compounds designed specifically for detecting protease activity. They are usually composed of a peptide segment that can be recognized and cleaved by a specific protease and a chromogenic or fluorophore. When the protease acts on the substrate, a chromogenic or fluorescent signal is released, thereby achieving quantitative analysis of protease activity. This type of dye is widely used in intracellular protease activity research, drug screening, and disease diagnosis.
- 4-MUNANA4-Methylumbelliferyl-N-acetyl-α-D-Neuraminic Acid sodium saltT3812076204-02-94-MUNANA is a fluorescent substrate employed in neuraminidase activity assays and serves as a neuraminidase substrate analogue.
- $31
SizeQTY - Nitro blue tetrazolium chlorideNBTT19032298-83-9Nitro blue tetrazolium chloride (NBT), an NADPH-diaphorase substrate (IC50 = 3-4 M) and well-known scavenger of superoxide anions, competitively inhibits nitric oxide synthase. Additionally, NBT, as a substrate for dehydrogenases, is used with the alkaline phosphatase substrate BCIP in western blotting and immunohistological staining procedures.
- $42
SizeQTY - ABTS diammonium saltAzBTS-(NH4)2T1890830931-67-0ABTS diammonium salt (AzBTS-(NH4)2) is a substrate of horseradish peroxidase.
- $35
SizeQTY - Boc-Gln-Ala-Arg-AMC hydrochlorideT74040201849-55-0Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorescent compound used as a substrate for trypsin and for assessing the protein hydrolysis activity of TMPRSS2.
- $47
SizeQTY - 4-Methylumbelliferyl oleateT7838618323-58-54-Methylumbelliferyl oleate is a fluorescent substrate for lipases (Ex/Em=320/450 nm), which can be cleaved by lipase and can be used to measure pancreatic inhibitory activity.
- $30
SizeQTY - X-Gluc Dicyclohexylamine5-Bromo-4-chloro-3-indolyl-beta-D-glucuronide cyclohexylammonium saltT1907618656-96-7X-Gluc Dicyclohexylamine (5-Bromo-4-chloro-3-indolyl-beta-D-glucuronide cyclohexylammonium salt) is a reagent to detect β-glucuronidase and can be used in molecular biology experiments to mark and select the expression of target genes.
- $30
SizeQTY - BCIPX-phosphate p-toluidine salt, BCIP p-toluidine saltT189236578-06-9BCIP (BCIP p-toluidine salt) (BCIP p-toluidine salt) is an artificial chromogenic substrate. It is used for the sensitive colorimetric detection of alkaline phosphatase activity.
- $85
SizeQTY - Ac-YVAD-AFCT78431219137-85-6Ac-YVAD-AFC is a fluorescent peptide substrate used to detect caspase-1. When cleaved, it releases the fluorescent molecule AFC, with an excitation wavelength of 400 nm and an emission wavelength of 505 nm.
- $44
SizeQTY - Z-IETD-AFCT36333219138-02-0Z-IETD-AFC is a fluorescent substrate for caspase-8 and granzyme B. It can be used to quantify cysteinyl aspartate-8 or granzyme B activity.
- $60
SizeQTY - MeOSuc-AAPV-AMCMeOSuc-Ala-Ala-Pro-Val-AMCT3836472252-90-5MeOSuc-AAPV-AMC (MeOSuc-Ala-Ala-Pro-Val-AMC) is a tetrapeptide that is a fluorescent substrate for human leukocyte and porcine pancreatic elastase.
- $40
SizeQTY - DansylcadaverineMonodansyl cadaverineT1896810121-91-2Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.
- $29
SizeQTY - 4-Methylumbelliferyl-β-D-glucuronide hydrateMUGT18887881005-91-04-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) is a fluorogenic substrate (λex=362 nm, λem=445 nm).
- $39
SizeQTY - IDT307IDT 307T385161141-41-9IDT307 is a fluorescent analog of MPP+, a fluorescent substrate for DAT (fluorescent substrate APP+), and can be used for rapid identification and characterization of PMAT inhibitors.
- $29
SizeQTY - BCDA5-bromo-4-chloroindoxyl acetateT188803252-36-6BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate utilized to detect esterase activity.
- $30
SizeQTY - Msr-RatioMsr-Ratio, Msr-greenT398172290635-22-0In houseMsr-Ratio (Msr-green) (Msr-green) is a ratiometric fluorescent probe specifically designed for the detection of methionine sulfoxide reductase (MSR) activity. It has an excitation wavelength of 375 nm and an emission wavelength of 550 nm. This probe offers the ability to monitor the enzyme activity both in vitro and in live cells, making it a valuable tool for studying MSR function.
- $30
SizeQTY
- 5-Bromo-4-chloro-3-indoxyl-beta-D-cellobiosideT60017177966-52-85-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases.
- $31
SizeQTY - EDANS sodiumN-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid Sodium Salt, EDANS sodium salt, EDANS sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt], 5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium saltTD0082100900-07-0EDANS sodium (5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt) is a donor for developing FRET-based nucleic acid probes that is widely used in real time PCR assays.
- $37
SizeQTY - Mca-YVADAP-Lys(Dnp)-OHT76090189696-01-3Mca-YVADAP-Lys(Dnp)-OH serves as a fluorogenic substrate specifically for caspase-1 and angiotensin-converting enzyme 2 (ACE2) [1].
- $195
SizeQTY - Gly-Gly-AMCH-Gly-Gly-AMCT82281208645-74-3Gly-Gly-AMC (H-Gly-Gly-AMC) is a fluorogenic substrate for cathepsin C, used for quantifying cathepsin C activity.
- $113
SizeQTY - 6-alkyne NAD+ sodiumβ-Nicotinamide-N6-propargyladenine dinucleotide sodium, Click Tag 6-alkyne NAD sodium, 6-Parg NAD sodium, 6-alkyne Nicotinamide adenine dinucleotide sodiumT837996-alkyne NAD+ sodium (6-Parg NAD sodium) is a clickable signaling molecule and enzyme cofactor in NAD+ form. It is used in conjunction with fluorescence labeling for detecting poly(ADP-ribose) polymerase (PARP) protein substrates.
- $1,300
SizeQTY - Boc-Val-Pro-Arg-MCA hydrochlorideBoc-Val-Pro-Arg-MCA HClT7840970375-24-5Boc-Val-Pro-Arg-MCA hydrochloride (Boc-Val-Pro-Arg-MCA HCl) is a sensitive fluorescent substrate for the determination of trypsin-like serine proteases activity.
- $91
SizeQTY - Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2T370251926163-82-7Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.
- $738
SizeQTY - Boc-Leu-Ser-Thr-Arg-AMCT8586873554-93-5Boc-Leu-Ser-Thr-Arg-AMC serves as a fluorogenic substrate linked with AMC for proteases [1].
- Inquiry Price
SizeQTY - 7-Methyl-6-thioguanosineMESGT1902555727-10-1MESG, a chromophoric substrate, can be used to quantitate inorganic phosphate.Inquiry
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