Powder: -20°C for 3 years
In solvent: -80°C for 2 years
(Rac)-Nedisertib is a racemate of Nedisertib, a potent inhibitor of <a href="/target/DNA_PK" style="display: inline; color: #c13a36">DNA-PK</a>(IC50 of <3 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 8-10 weeks | $ 970.00 | |
50 mg | 8-10 weeks | $ 1,980.00 | |
100 mg | 8-10 weeks | $ 2,500.00 |
Description | (Rac)-Nedisertib is a racemate of Nedisertib, a potent inhibitor of DNA-PK(IC50 of <3 nM). |
Targets&IC50 | DNA-PK:3 nM |
In vitro | (Rac)-Nedisertib potently inhibits DNA-PK with an IC50 of <3 nM for DNA-PK, 0.5-5 μM for cellular pDNA-PK and 15-25 μM for KV11.1 (hERG, human ether a-go-go related gene). |
Synonyms | (Rac)-M3814 |
Molecular Weight | 481.91 |
Formula | C24H21ClFN5O3 |
CAS No. | 1637542-34-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 100 mg/mL (207.51 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(Rac)-Nedisertib 1637542-34-7 DNA Damage/DNA Repair PI3K/Akt/mTOR signaling DNA-PK (Rac)Nedisertib (Rac)-M3814 (Rac) Nedisertib Inhibitor inhibitor inhibit