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Cat No. | Product Name | Synonyms | Targets |
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T14494 | Balovaptan | RG7314 | Vasopressin Receptor |
Balovaptan (RG7314) is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors. It is used for the research of autism. | |||
T64174 | Vasopressin V2 receptor antagonist 1 | ||
Vasopressin V2 receptor antagonist 1 (Compound 4g) is a vasopressin V2receptor (V2R) antagonist (Ki: 3.8 nM). dominant polycystic kidney disease (ADPKD). | |||
T6288 | Mozavaptan | OPC31260l,OPC-31260 | Vasopressin Receptor |
Mozavaptan (OPC-31260) is a competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively. | |||
T4355 | Fuscoside | OPC 21268 | Vasopressin Receptor |
Fuscoside (OPC 21268) is a non-peptide Arginine vasopressin(AVP) Receptor V antagonist. | |||
T11857 | LIT-001 | Oxytocin Receptor | |
LIT-001 improves social interaction in a mouse model of autism.It is the first nonpeptide oxytocin receptor agonist with EC50 of 55 nM and Ki of 226 nM. | |||
T13920L | Terlipressin Acetate | Terlipressin diacetate anhydrous,Terlipressin acetate anhydrous | Vasopressin Receptor |
Terlipressin Acetate, a highly selective vasopressin V1 receptor agonist, on oxygen and glucose deprivation/re-oxygenation (OGD/R)-induced damage in intestinal epithelial cells (IEC-6).Terlipressin acetate exerts anti-in... | |||
T5148 | Atosiban acetate | RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164 | Oxytocin Receptor , Vasopressin Receptor |
Atosiban acetate (RW22164) is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban acetate (RW22164) inhibits... | |||
T2326 | Tolvaptan | OPC-41061 | Vasopressin Receptor , Autophagy |
Tolvaptan (OPC-41061) is an orally bioavailable, selective, arginine vasopressin receptor 2 (V2, AVPR2) antagonist that can be used to treat hyponatremia. | |||
T7303 | LIXIVAPTAN | VPA-985,WAY-VPA 985 | Vasopressin Receptor |
Lixivaptan (VPA-985) is an orally active and selective vasopressin receptor V2 antagonist(Ki = 2.3 nM) | |||
T6453 | Conivaptan hydrochloride | Vaprisol,Conivaptan HCl,YM 087 | Vasopressin Receptor |
Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist, used in the therapy of hypervolemic hyponatremia and euvolemic. | |||
T7434 | Argipressin | Arg8-vasopressin,Vasopressin,AVP | Vasopressin Receptor |
Argipressin (Vasopressin) is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth ... | |||
T2568 | Felypressin | Octapressin,Felypressin Acetate,PLV-2,H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2 | Vasopressin Receptor |
Felypressin (Octapressin) is a synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activity. | |||
T2568L | Felypressin acetate | 2-(L-Phenylalanine)-8-L-lysinevasopressin,PLV2. H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond),PLV 2,PLV-2 | Vasopressin Receptor |
Felypressin acetate (PLV-2) is an agonist of vasopressin 1 and acts on all arginine vasopressin receptors 1AS. Felypressin acetate can be used in dental procedures. | |||
T4996 | Atosiban | RWJ22164,RW22164 | Oxytocin Receptor , Vasopressin Receptor |
Atosiban (RW22164) is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhibits the oxytocin-mediated rel... | |||
T4141 | RG7713 | RO 5028442 | Vasopressin Receptor |
RG7713 (RO 5028442) has been used in trials studying Autistic Disorder. | |||
T21308 | Histrelin | Supprelin LA,Histrelin Acetate | Others |
Histrelin (Supprelin LA) acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It is considered a GnRH agonist. Histrelin is used in the treatment of hormone-sensitive cancers of th... | |||
T28153 | Nelivaptan | SSR149415,SR 149415,SR-149415 | Vasopressin Receptor |
Nelivaptan (SR 149415) is a vasopressin V1b receptor antagonist. | |||
T7284 | Argipressin acetate (113-79-1(free base)) | Others | |
Vasopressin acetate is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle... | |||
T15682 | L-371,257 | Oxytocin Receptor , Vasopressin Receptor | |
L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a. | |||
T5144 | Desmopressin acetate (16679-58-6 free base) | Desmopressin acetate,DDAVP | Vasopressin Receptor |
Desmopressin acetate (16679-58-6 free base) (DDAVP) is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyur... | |||
T15273 | Fedovapagon | VA483,A106483 | Vasopressin Receptor |
Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. Fedovapagon can be used to study overactive bladder, nocturia... | |||
TP1192L | Conopressin S acetate(111317-90-9 free base) | Con-S acetate | Vasopressin Receptor |
Conopressin S acetate(111317-90-9 free base) (Con-S acetate) is a natural product isolated from Conus striatus, shows high affinity with vasopressin V1b receptor (AVPR1B), with a Ki of 8.3 nM. | |||
TP1927L1 | D[Leu4,Lys8]-VP acetate | d[Leu4,Lys8]-VP acetate(42061-33-6 free base) | Vasopressin Receptor |
d[Leu4,Lys8]-VP acetate is a selective vasopressin V1b receptor agonist. The Kis for rat, human and mouse V1b receptors are 0.16 nM, 0.52 nM and 0.1.38 nM, respectively. d[Leu4,Lys8]-VP acetate exhibits weak antidiuretic... | |||
TP2082L | D[Cha4]-AVP acetate(500170-27-4 free base) | Vasopressin Receptor | |
d[Cha4]-AVP acetate is a potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secre... | |||
T23393 | SR 49059 | Others | |
vasopressin V1A receptor antagonist | |||
T28745 | Selepressin | FE 202158,FE202158 | |
Selepressin, an analog of vasopressin, is a potent, selective vasopressin V1a receptor agonist. | |||
T28629 | RWJ 676070 | RWJ676070,RWJ-676070 | |
RWJ 676070 is an antagonist of vasopressin V1A/V2 receptor. | |||
T29085 | VA-111913 | VA111913,VA 111913 | |
VA-111913, a vasopressin receptor antagonist, is used potentially for the treatment of dysmenorrhea. | |||
T70066 | Pecavaptan | ||
Pecavaptan is a vasopressin receptor antagonist. | |||
T21465 | Mozavaptan hydrochloride | OPC-31260,OPC31260,Mozavaptan HCl,OPC 31260 | |
Mozavaptan is a vasopressin receptor antagonist. | |||
T34325 | Ribuvaptan | ||
Ribuvaptan is a antagonist of vasopressin receptor . | |||
T29177 | YM 218 | YM218,YM-218 | |
YM 218 is a novel, potent, selective antagonist of nonpeptide vasopressin V1A receptor. | |||
T76509 | Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin | ||
Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), is a weak agonist at antidiuretic receptor . However, Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin is a potent agonist at pit... | |||
T39611 | Enuvaptan | Enuvaptan,BAY-2327949 | |
Enuvaptan is a vasopressin receptor antagonist and has the potential for research into renal and cardiovascular diseases. | |||
T29178 | YM 471 | YM-471,YM471 | |
YM 471 is a non-peptide arginine vasopressin (AVP) V1A and V2 receptor antagonist with oral activity. | |||
T24759 | Satavaptan fumarate | SR-121463A,SR 121463 A,SR-121463 A,SR121463A | |
Satavaptan fumarate is a selective antagonist of the non-peptide vasopressin V2 receptor. | |||
T76633 | (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin | ||
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin is a potent vasopressin V1 receptor (VP V1R) antagonist. (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin significantly decreases the mean arterial pressure (MAP... | |||
T27965 | M-0002 | RWJ-351647,SPD556,SPD-556,M0002,RWJ351647 | |
M-0002, a vasopressin V2 receptor antagonist, is used potentially for the treatment of ascites. | |||
T28664 | Satavaptan | SR121463,SR 121463,SR-121463 | |
Satavaptan is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis. | |||
T28854 | SRX 251 | SRX-251,SRX251 | |
SRX 251, a vasopressin V1a receptor antagonist, is used potentially for the treatment of primary dysmenorrhea. | |||
T80073 | Dp[Tyr(methyl)2,Arg8]-Vasopressin | Vasopressin Receptor | |
Dp[Tyr(Me)2,Arg8]-Vasopressin is a non-selective antagonist of the peptide arginine vasopressin V1b receptor [1]. | |||
TP2136 | (d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin | ||
Selective vasopressin V1A receptor antagonist. Inhibits vasopressin and oxytocin-induced increases in intracellular calcium concentrations in vitro (IC50 values are 5 and 30 nM respectively). Exhibits potent and prolonge... | |||
T79173 | PF-06478939 | Oxytocin Receptor | |
PF-06478939 is a peptide that functions as an agonist at the oxytocin (OT) receptor and vasopressin receptor without crossing the blood-brain barrier. It exhibits EC50 values of 0.01 nM at the OT receptor and 0.078 nM at... | |||
T24370 | L-368899 free base | L 368899,L 368,899,L368,899,L-368899,L368899,L-368,899 | |
L-368899 is a non-peptide and orally active antagonist of oxytocin receptor (IC50: 8.9 nM). It displays 40-fold selectivity over vasopressin V1a and V2 receptors (IC50: 370 and 570 nM respectively). | |||
T17251 | VNA-932 | WAY-VNA 932 | Others |
VNA-932 is an agonist of the vasopressin V2-receptor (IC50: 80.3 nM and 778 nM in human-V2 binding and V1a binding assay). | |||
T30275 | Azilsartan trimethylethanolamine | Azilsartan,TAK-536 | |
Azilsartan is an angiotensin II receptor antagonist for the treatment of hypertension and was developed by Takeda. Azilsartan Medoxomil lowers blood pressure by blocking the effects of angiotensin II, a type of vasopress... | |||
T62906 | Lazuvapagon | ||
Lazuvapagon is a vasopressin V2 receptor agonist that can be used to study enuresis. | |||
T80270 | Invopressin | OCE-205 | Vasopressin Receptor |
Invopressin (Compound 42), a vasopressin V1A receptor partial agonist (EC50: 1.0 nM), is utilized in research related to cirrhosis conditions such as bacterial peritonitis, HRS2, and refractory ascites [1]. | |||
T80137 | (d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin | d(CH2)5[Tyr(Me)2, Dab5]AVP | Vasopressin Receptor |
(d(CH2)5[Tyr(Me)2, Dab5]AVP), a vasopressin V1a receptor-specific antagonist, demonstrates a pA2 value of 6.71 [1]. | |||
TP1192 | Conopressin S | Con-S | |
Conopressin S, isolated from Conus striatus, shows high affinity with vasopressin V1b receptor (AVPR1B), with a Ki of 8.3 nM. |
Cat No. | Product Name | Species | Expression System |
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TMPH-02818 | Osteocalcin Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption. | |||
TMPH-01589 | KIR2DS3 Protein, Human, Recombinant (His) | Human | Yeast |
Secreted polyprotein that is packaged and proteolytically processed by prohormone convertases PCSK1 and PCSK2 in a cell-type-specific manner. VGF and peptides derived from its processing play many roles in neurogenesis a... |
Cat No. | Product Name | ||
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L7110 | Anti-Hypertension Compound Library | 719 compounds | |
719 hypertension-related small molecules for high-throughput and high-content screening. |