TN1235 |
3,4,5-Tricaffeoylquinic acid
|
86632-03-3
|
98%
|
|
3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like rece...
|
TN1543 |
Cynaropicrin
|
35730-78-0
|
98%
|
|
Cynaropicrin is a potent activator of the AhR-Nrf2-Nqo1 pathway, and could therefore be applied to prevention of UVB-induced photo aging; it may be a potential a...
|
TN3219 |
7,8-Didehydrocimigenol
|
150972-72-8
|
98%
|
|
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of ...
|
T11442 |
GNE684
|
2438637-64-8
|
98%
|
|
GNE684 is a potent inhibitor of potent receptor interacting protein 1 (RIP1) with average Ki app values of 21 nM, 189 nM and 691 nM for human mouse and rat RIP1,...
|
TN3708 |
Coronarin D
|
119188-37-3
|
98%
|
|
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
TN3779 |
De-O-methyllasiodiplodin
|
32885-82-8
|
98%
|
|
De-O-methyllasiodiplodin exhibits radical scavenging, moderate antibacterial, and potential anti-inflammatory effects, it shows moderate suppression effects on i...
|
TN2243 |
Sugiol
|
511-05-7
|
98%
|
|
Sugiol (10-Deoxoxanthoperol) has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and h...
|
T2S0606 |
Bakkenolide A
|
19906-72-0
|
98%
|
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
|
TN3298 |
8alpha-Hydroxyhirsutinolide
|
1394156-45-6
|
98%
|
|
8alpha-Hydroxyhirsutinolide shows anti-inflammatory activity, it inhibits TNF-α-induced NF-κB activity with the IC(50) value of 1.9 uM.
|
TN4986 |
Selinidin
|
19427-82-8
|
98%
|
|
Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.
|
T12985L |
SPD304
|
869998-49-2
|
98%
|
|
SPD304 is a selective TNF-α inhibitor and blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 µM for inhibiting in vitro TNF receptor 1 bind...
|
TN4093 |
Galeopsin
|
76475-16-6
|
98%
|
|
Galeopsin shows potential anti-inflammatory activity by inhibiting proinflammatory cytokine TNF-α, it has anti-proliferative effect on several cancer cell lines....
|
TN2178 |
Sanggenone H
|
86450-80-8
|
98%
|
|
Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α± and IL-1α² and inhibited the NF-κB nuclear translocation in LPS-stimulated m...
|
TN4190 |
Hedycoronen A
|
1383441-73-3
|
98%
|
|
Hedycoronen A and hedycoronen B have the potential anti-inflammatory benefits, they are potent inhibitors of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, w...
|
TN4776 |
Physalin D
|
54980-22-2
|
98%
|
|
Physalin D shows antimalarial activity; it also exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 m...
|
TN4392 |
Koaburaside
|
41653-73-0
|
98%
|
|
Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have ...
|
TN2149 |
Reynosin
|
28254-53-7
|
98%
|
|
Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reci...
|
TN5912 |
Macluraxanthone
|
5848-14-6
|
98%
|
|
Macluraxanthone (3-Hydroxyblancoxanthone) has many biological activities including anticholinesterase, antioxidant, anticancer, antimalarial, anti-inflammatory a...
|
TN2588 |
11-Hydroxytephrosin
|
72458-85-6
|
98%
|
|
11-Hydroxytephrosin inhibits NF-kappaB activity.
|