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Search Results for " sigma-1 receptor "

Targets

42

Compounds

1728

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T12910 Sigma-1 receptor antagonist 1 Sigma receptor
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studie...
T12911 Sigma-1 receptor antagonist 2 Sigma receptor
Sigma-1 receptor antagonist 2 is a potent and selective antagonist of sigma 1 receptor1 R) (σ1 and σ2 receptor with Kis of 3.88 and 1288 nM , respectively).
T12912 Sigma-1 receptor antagonist 3 Sigma receptor , HER
Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-11) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain.
T16883 Sigma-2 receptor antagonist 1 Others
Sigma-2 receptor antagonist 1 is an antagonist of the sigma-2 (σ-2) receptor.
T9244 σ1 Receptor antagonist-1 Sigma receptor
σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.
T78734 Sigma-1 receptor antagonist 5 Sigma receptor
Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic action on sigma receptors (Ki=4.5 nM (σ1R), 10 nM (σ2R)) and the histamine H3 receptor...
T4229 S1RA hydrochloride E-52862 hydrochloride Sigma receptor
S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki > 1000 nM).
T1865 S1RA E-52862 Sigma receptor
S1RA (E-52862)(E-52862) is a potent and selective sigma-1 receptor1R, Ki=17 nM) antagonist, showed good selectivity against σ2R (Ki > 1000 nM).
T13510 Sigma-LIGAND-1 Sigma receptor
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor.
T5027 Dimemorfan phosphate 3,17-dimethylmorphinan Sigma receptor
Dimemorfan phosphate (3,17-dimethylmorphinan) is a sigma 1 receptor agonist. Dimemorfan phosphate is used as a potent antitussive.
T4111 Blarcamesine hydrochloride Anavex 2-73,AVex-73 hydrochloride,AE-37 hydrochloride Sigma receptor
Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).
T7488 BD1063 dhydrochloride BD1063 Sigma receptor
BD1063 dhydrochloride is a potent and selective sigma 11) receptor antagonist(Ki = 9 nM).
T79499 KSK68 Histamine Receptor
KSK68 is a potent dual sigma-1 and histamine H3 receptor antagonist with potential analgesic activity and high affinity for H3 receptors, sigma-1, sigma-2 receptors.KSK68 can be used in the study of pain related diseases...
T79500 KSK94 Histamine Receptor
KSK94 is a specific H3 receptor antagonist that inhibits H3, sigma-1, and sigma-2 receptors , with Ki values of 7.9, 2958, and 75.2 nM, respectively, and can be used to study injurious pain and neuropathic pain.
T1186L Ifenprodil RC 61-91,RC-61-91,RC61-91,RC 6191 Adrenergic Receptor , NMDAR
Ifenprodil (RC61-91) is an inhibitor of the NMDA receptor, specifically of GluN1 (glycine-binding NMDA receptor subunit 1) and GluN2B (glutamate-binding NMDA receptor subunit 2) subunits. Additionally, Ifenprodil inhibit...
T1885 Siramesine hydrochloride Lu 28-179 hydrochloride Ferroptosis , Sigma receptor , lysosomal autophagy
Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent anticancer activity in vivo.
T21788 BD 1008 dihydrobromide Sigma receptor
BD 1008 dihydrobromide is a selective antagonist of the sigma 11) receptor (Ki = 2 nM). BD 1008 dihydrobromide have high affinity for sigma1 receptors, moderate affinity for sigma2 receptors.
T1740 BD-1047 dihydrobromide BD1047.2HBr Sigma receptor
BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacy in schizophrenia.
T39211 PD 144418 oxalate Sigma receptor
PD 144418 oxalate is a highly potent and selective sigma 11) receptor ligand, displaying a Ki value of 0.08 nM for σ1 and 1377 nM for σ2. It exhibits negligible affinity for other receptors, ion channels, and enzymes....
T5389 Volinanserin M 100907,MDL100907 5-HT Receptor
Volinanserin (MDL100907) (MDL 100907) is a potent and selective antagonist of the serotonin receptor 5-HT2 (Ki: 0.36 nM) and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 adrenergic and sigma recepto...
T22870 IPAG Opioid Receptor
IPAG is a potent σ-receptor antagonist (pKi=4.3). IPAG can induce cell apoptosis.
T60835 SKF83959 Dopamine Receptor
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.SKF83959 is a potent ...
T8834 EST64454 hydrochloride EST64454 Sigma receptor
EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.
T7352 Pridopidine ACR16,ASP2314,FR310826 Dopamine Receptor
Pridopidine (FR310826), a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model.
T79500L KSK94 FA KSK94 FA(2566716-07-0 Free base) Histamine Receptor
KSK94 FA is a potent histamine H3 receptor antagonist that inhibits H3 receptors and is used in the study of neuropathic pain and obesity.
T25584 KSCM-1 KSCM 1
KSCM-1 is a selective sigma-1 receptor ligand.
T70809 BD 1008 Free Base
BD 1008 Free Base is a selective sigma receptor antagonist, with a reported binding affinity of Kᵢ = 2 ± 1 nM for the sigma-1 receptor and 4 times selectivity over the sigma-2 receptor.
T63048 Sigma-LIGAND-1 hydrochloride
Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand that acts at the DTG (IC50: 16 nM) and PPP (IC50: 19 nM) sites. Sigma-LIGAND-1 hydrochloride is able to act on the dopamine D2 receptor (Ki: 4000 nM).
T10093L E1R Others
E1R is a positive sigma-1 receptor (Sig1R PAM) allosteric modulator. It has a cognition-enhancing activity.
T71949 CM304
CM304 is a highly selective sigma-1 receptor antagonist.
T10093 (2R,3R)-E1R Others
(2R,3R)-E1R is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders.
T10097 (2S,3S)-E1R Others
(2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders.
T10094 (2R,3S)-E1R Others
(2R,3S)-E1R (Compound 2c) is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders.
T61376 Opipramol
Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) that primarily acts as a sigma (σ) receptor agonist, exhibiting potent interaction with sigma recognition sites (K i value of 50 nM). It can be employed i...
T12665 (Rac)-E1R Others
(Rac)-E1R is the racemate of E1R. (Rac)-E1R is a sigma-1 receptor positive allosteric (Sig1R PAM) modulator of for the treatment of cognition/memory disorders.
T61846 CM398
CM398 is an orally active chemical compound that acts as a highly selective ligand for the sigma-2 receptor (K i =0.43 nM), demonstrating a significant ratio of selectivity between sigma-1 and sigma-2 receptors (1000-fol...
T16445 PD 144418 Sigma receptor
PD 144418 displays potential antipsychotic activity. PD 144418 is a high affinity, potent and selective sigma 11) receptor ligand (Ki: 0.08 nM and 1377 nM for σ1 and σ2 respectively). It shows devoid of any significan...
T60391 Phenyltoloxamine
Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity with Ki of 160 nM [1] [2] [3].
T39176 PB28
PB28 is a cyclohexylpiperazine derivative that functions as a potent and highly selective agonist of the sigma 2 (σ2) receptor, exhibiting a Ki (binding affinity) of 0.68 nM. At the same time, PB28 acts as an antagonist ...
T79356 SARS-CoV-2-IN-57 Sigma receptor
SARS-CoV-2-IN-57 (compound (+)-R-26) is a potent inhibitor of SARS-CoV-2 with an IC50 of 80 nM and demonstrates high affinity for the Sigma Receptor, exhibiting Kis of 13.6 nM (S1R) and 14.4 nM (S2R) [1].
T4620 Siramesine Lu 28-179 Sigma receptor
Siramesine (Lu 28-179)(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer activity in vivo.lysosome-destabilizing agent siram...
T36639 Donecopride (fumarate hydrate)
Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= ...

Compounds

Sigma-1 receptor antagonist 1
T12910
Synonym:
Target: Sigma receptor
Sigma-1 receptor antagonist 2
T12911
Synonym:
Target: Sigma receptor
Sigma-1 receptor antagonist 3
T12912
Synonym:
Target: Sigma receptor, HER
Sigma-2 receptor antagonist 1
T16883
Synonym:
Target: Others
σ1 Receptor antagonist-1
T9244
Synonym:
Target: Sigma receptor
Sigma-1 receptor antagonist 5
T78734
Synonym:
Target: Sigma receptor
S1RA hydrochloride
T4229
Synonym: E-52862 hydrochloride
Target: Sigma receptor
S1RA
T1865
Synonym: E-52862
Target: Sigma receptor
Sigma-LIGAND-1
T13510
Synonym:
Target: Sigma receptor
Dimemorfan phosphate
T5027
Synonym: 3,17-dimethylmorphinan
Target: Sigma receptor
Blarcamesine hydrochloride
T4111
Synonym: Anavex 2-73,AVex-73 hydrochloride,AE-37 hydrochloride
Target: Sigma receptor
BD1063 dhydrochloride
T7488
Synonym: BD1063
Target: Sigma receptor
KSK68
T79499
Synonym:
Target: Histamine Receptor
KSK94
T79500
Synonym:
Target: Histamine Receptor
Ifenprodil
T1186L
Synonym: RC 61-91,RC-61-91,RC61-91,RC 6191
Target: Adrenergic Receptor, NMDAR
Siramesine hydrochloride
T1885
Synonym: Lu 28-179 hydrochloride
Target: Ferroptosis, Sigma receptor, lysosomal autophagy
BD 1008 dihydrobromide
T21788
Synonym:
Target: Sigma receptor
BD-1047 dihydrobromide
T1740
Synonym: BD1047.2HBr
Target: Sigma receptor
PD 144418 oxalate
T39211
Synonym:
Target: Sigma receptor
Volinanserin
T5389
Synonym: M 100907,MDL100907
Target: 5-HT Receptor
IPAG
T22870
Synonym:
Target: Opioid Receptor
SKF83959
T60835
Synonym:
Target: Dopamine Receptor
EST64454 hydrochloride
T8834
Synonym: EST64454
Target: Sigma receptor
Pridopidine
T7352
Synonym: ACR16,ASP2314,FR310826
Target: Dopamine Receptor
KSK94 FA
T79500L
Synonym: KSK94 FA(2566716-07-0 Free base)
Target: Histamine Receptor
KSCM-1
T25584
Synonym: KSCM 1
Target:
BD 1008 Free Base
T70809
Synonym:
Target:
Sigma-LIGAND-1 hydrochloride
T63048
Synonym:
Target:
E1R
T10093L
Synonym:
Target: Others
CM304
T71949
Synonym:
Target:
(2R,3R)-E1R
T10093
Synonym:
Target: Others
(2S,3S)-E1R
T10097
Synonym:
Target: Others
(2R,3S)-E1R
T10094
Synonym:
Target: Others
Opipramol
T61376
Synonym:
Target:
(Rac)-E1R
T12665
Synonym:
Target: Others
CM398
T61846
Synonym:
Target:
PD 144418
T16445
Synonym:
Target: Sigma receptor
Phenyltoloxamine
T60391
Synonym:
Target:
PB28
T39176
Synonym:
Target:
SARS-CoV-2-IN-57
T79356
Synonym:
Target: Sigma receptor
Siramesine
T4620
Synonym: Lu 28-179
Target: Sigma receptor
Donecopride (fumarate hydrate)
T36639
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-00699 CD155/PVR Protein, Human, Recombinant (hFc) Human HEK293
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-01776 Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) Human HEK293
Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and...
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-00654 ACVR2B Protein, Human, Recombinant (hFc) Human HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-03947 CD48 Protein, Human, Recombinant (hFc) Human HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-00586 CLEC-2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPY-02121 CXADR/CAR Protein, Human, Recombinant (His) Human HEK293
CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. ...
TMPY-01829 CD83 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00399 HER3/ERBB3 Protein, Human, Recombinant Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPK-00114 C-Reactive Protein /CRP Protein, Human, Recombinant (His) Human HEK293
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPY-05239 HER2/ERBB2 Protein, Human, Recombinant , Biotinylated Human HEK293
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01037 CSF1R Protein (Met1-Glu512), Human, Recombinant (His) Human HEK293
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-01226 CD4 Protein, Mouse, Recombinant (His) Mouse HEK293
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-01023 CD38 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05364 CD8 alpha Protein, Human, Recombinant (hFc) Human HEK293
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-02031 B7-H3 Protein, Human, Recombinant (His) Human HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-01050 Cadherin 6/CDH6 Protein, Human, Recombinant (His) Human HEK293
Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progres...
TMPY-03363 C-Reactive Protein Protein, Human, Recombinant Human HEK293
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reacti...
TMPY-01608 Decorin Protein, Human, Recombinant (His) Human HEK293
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPY-02019 CD59 Protein, Human, Recombinant (His) Human HEK293
CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran...
TMPY-02099 CD63 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-05319 BCMA/TNFRSF17 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-04262 B7-H3 Protein, Human, Recombinant (His), Biotinylated Human HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-00978 Progranulin Protein, Human, Recombinant (His) Human HEK293
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ...
TMPY-02034 Siglec-2/CD22 Protein, Human, Recombinant (His) Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) Human HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His) Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-03407 NQO1 Protein, Human, Recombinant (His) Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-...
TMPY-02227 IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) Rat E. coli
Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-04753 IRE1 Protein, Human, Recombinant (aa 465-977) Human Baculovirus-Insect Cells
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPY-06077 LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc) Human HEK293
TMPY-02361 VEGFR2/KDR Protein, Human, Recombinant (His) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-05208 PD-L1 Protein, Human, Recombinant Human HEK293
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-01853 SIRP gamma Protein, Human, Recombinant (His) Human HEK293
Signal-regulatory protein gamma (SIRPG/SIRP gamma) also known as CD172 antigen-like family member B, CD172g, and CD172g antigen, is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunog...
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc) Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His) Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r...
TMPY-02647 IFNAR1 Protein, Human, Recombinant (His) Human HEK293
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His) Human,Rhesus HEK293
ERBB4 is a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. ERBB4 is ...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc) Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His) Human HEK293
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-01166 TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-01283 Glypican 3/GPC3 Protein, Human, Recombinant (His) Human HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-01851 CD73 Protein, Human, Recombinant (His) Human HEK293
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-00772 DC-SIGN Protein, Human, Recombinant (hFc) Human HEK293
Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable...
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) Human HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, includi...
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AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus-Insect Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293
CD155/PVR Protein, Human, Recombinant (hFc)
TMPY-00699
Species: Human
Expression System: HEK293
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His)
TMPY-01776
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
TMPY-00664
Species: Human
Expression System: HEK293
ACVR2B Protein, Human, Recombinant (hFc)
TMPY-00654
Species: Human
Expression System: HEK293
CD48 Protein, Human, Recombinant (hFc)
TMPY-03947
Species: Human
Expression System: HEK293
CLEC-2 Protein, Mouse, Recombinant (hFc)
TMPY-00586
Species: Mouse
Expression System: HEK293
CXADR/CAR Protein, Human, Recombinant (His)
TMPY-02121
Species: Human
Expression System: HEK293
CD83 Protein, Human, Recombinant (His)
TMPY-01829
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant
TMPY-00399
Species: Human
Expression System: HEK293
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
TMPK-00114
Species: Human
Expression System: HEK293
HER2/ERBB2 Protein, Human, Recombinant , Biotinylated
TMPY-05239
Species: Human
Expression System: HEK293
CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
TMPY-01037
Species: Human
Expression System: HEK293
CD4 Protein, Mouse, Recombinant (His)
TMPY-01226
Species: Mouse
Expression System: HEK293
CD38 Protein, Human, Recombinant (His)
TMPY-01023
Species: Human
Expression System: HEK293
CD8 alpha Protein, Human, Recombinant (hFc)
TMPY-05364
Species: Human
Expression System: HEK293
B7-H3 Protein, Human, Recombinant (His)
TMPY-02031
Species: Human
Expression System: HEK293
Cadherin 6/CDH6 Protein, Human, Recombinant (His)
TMPY-01050
Species: Human
Expression System: HEK293
C-Reactive Protein Protein, Human, Recombinant
TMPY-03363
Species: Human
Expression System: HEK293
Decorin Protein, Human, Recombinant (His)
TMPY-01608
Species: Human
Expression System: HEK293
CD59 Protein, Human, Recombinant (His)
TMPY-02019
Species: Human
Expression System: HEK293
CD63 Protein, Human, Recombinant (His)
TMPY-02099
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
TMPY-05319
Species: Human
Expression System: HEK293
B7-H3 Protein, Human, Recombinant (His), Biotinylated
TMPY-04262
Species: Human
Expression System: HEK293
Progranulin Protein, Human, Recombinant (His)
TMPY-00978
Species: Human
Expression System: HEK293
Siglec-2/CD22 Protein, Human, Recombinant (His)
TMPY-02034
Species: Human
Expression System: HEK293
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
TMPY-05435
Species: Human
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant (His)
TMPY-04348
Species: Human
Expression System: HEK293
NQO1 Protein, Human, Recombinant (His)
TMPY-03407
Species: Human
Expression System: E. coli
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)
TMPY-02227
Species: Rat
Expression System: E. coli
IRE1 Protein, Human, Recombinant (aa 465-977)
TMPY-04753
Species: Human
Expression System: Baculovirus-Insect Cells
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc)
TMPY-06077
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (His)
TMPY-02361
Species: Human
Expression System: HEK293
PD-L1 Protein, Human, Recombinant
TMPY-05208
Species: Human
Expression System: HEK293
SIRP gamma Protein, Human, Recombinant (His)
TMPY-01853
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
TMPY-01936
Species: Mouse
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (hFc)
TMPY-00947
Species: Human
Expression System: HEK293
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
TMPY-01912
Species: Human
Expression System: HEK293
IFNAR1 Protein, Human, Recombinant (His)
TMPY-02647
Species: Human
Expression System: HEK293
ErbB4 Protein, Human, Rhesus, Recombinant (His)
TMPY-02813
Species: Human,Rhesus
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc)
TMPY-04970
Species: Human
Expression System: HEK293
CD30/TNFRSF8 Protein, Human, Recombinant (His)
TMPY-01827
Species: Human
Expression System: HEK293
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)
TMPY-01166
Species: Human
Expression System: HEK293
Glypican 3/GPC3 Protein, Human, Recombinant (His)
TMPY-01283
Species: Human
Expression System: HEK293
CD73 Protein, Human, Recombinant (His)
TMPY-01851
Species: Human
Expression System: HEK293
DC-SIGN Protein, Human, Recombinant (hFc)
TMPY-00772
Species: Human
Expression System: HEK293
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
TMPY-01462
Species: Human
Expression System: HEK293
TargetMol