Carbonic Anhydrase

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes. The enzyme maintains acid-base balance and helps transport carbon dioxide.

Cat. No.	Product name	CAS No.	Purity
T77560	Histone acetyltransferase p300 Inhibitor 4c	2103-99-3	99.86%
T77560	Histone acetyltransferase p300 Inhibitor 4c is a 2-aminothiazole derivative. Histone acetyltransferase p300 Inhibitor 4c inhibited hCA I, hCA II, AChE and BChE w...
T38808	Cyclamic acid sodium	139-05-9	99.84%
T38808	Cyclamic acid sodium (Cyclohexylsulfamicacidsodium) is a carbonic anhydrase inhibitor and one of the most widely used artificial sweeteners in food and pharmaceu...
T2616	PIK-93	593960-11-3	99.83%
T2616	PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
T6503	Fluorometholone Acetate	3801-06-7	99.77%
T6503	Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
T6S0221	Eriocitrin	13463-28-0	99.77%
T6S0221	1. Eriocitrin (Eriodictyol-7-O-Rutinoside) is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress....
T0465	Ellagic acid	476-66-4	99.76%
T0465	Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the ...
T1409	Methocarbamol	532-03-6	99.75%
T1409	Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment...
T67774	Compound CDy9	952306-80-8	99.75%
T67774	Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.
T34093	PNNP	330-13-2	99.73%
T34093	pNNP (Nitrophenylphosphate) can be used as a substrate for the PP2C assay. pNNP inhibits β-carbonic anhydrase and α-carbonate dehydrogenase, as well as H. pylori...
T25372	EMD57033	147527-31-9	99.72%
T25372	EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to pro...
T2530	Levosimendan	141505-33-1	99.7%
T2530	Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart...
T2134	Dorzolamide hydrochloride	130693-82-2	99.48%
T2134	Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that ...
T1999	Taselisib	1282512-48-4	99.46%
T1999	Taselisib (GDC-0032) is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplasti...
T9323	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide	654-62-6	99.34%
T9323	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-tumor...
T0782	Benzthiazide	91-33-8	99.34%
T0782	Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). Th...
T0114	Trichlormethiazide	133-67-5	99.32%
T0114	Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazid...
T77631	Enpp/Carbonic anhydrase-IN-2	2883495-39-2	99.13%
T77631	Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.0...
T4321	Indisulam	165668-41-7	99.07%
T4321	Indisulam (E 7070) is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing...
T68136	(Iso)-Samixogrel	133276-52-5	98.67%
T68136	(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.
T73177	HCAII-IN-9	2878477-18-8	98.63%
T73177	hCAII-IN-9 is a potent carbonic anhydrase inhibitor that inhibits hCA II, hCA IX, and hCA XII with IC50s of 1.18 μM and 0.17 μM , and 2.99 μM , respectively. hCA...