uridine

Uridine (Uridin) is a nucleoside compound, one of the four bases that make up RNA, that replaces thymine in DNA during transcription and pairs with adenine.

Uridine,2',3'-o-(1-methylethylidene)-,4-oxidechemicalbook,5'-(2-methylpropanoate) is a pharmaceutical intermediate used in the synthesis of various active compounds.

Uridine triacetate (RG 2133 triacetate) (Tri-O-acetyl uridine), an orally active prodrug of uridine, is efficiently absorbed in the gut and swiftly deacetylated in the circulation to release free uridine. It is utilized in the research of 5-fluorouracil (5-FU) and capecitabine toxicity, particularly targeting early-onset cardiac or central nervous system (CNS) complications.

Uridine triphosphate trisodium salt (UTP, Trisodium Salt) is a nucleotide.

Uridine triphosphate (Uridine 5'-triphosphate) increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.

5-Bromouridine is a uracil derivative with a broad spectrum of antitumor activity that induces apoptosis in cancer cells by inhibiting DNA synthesis.5-Bromouridine is also used as a marker for DNA and RNA, where the molecule is labeled with a radioisotope or pigment after being introduced into a DNA or RNA strand.

L-Uridine is the enantiomer of D-uridine, a nucleoside that acts as a phosphate acceptor for nucleoside phosphotransferase, in the normal RNA component of a normal RNA isolated from Polyporaceae fungus Poria cocos (Schw.) L-Uridine has potential antiviral activity.

Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. Uridine-5'-diphosphate disodium salt also acts as an antagonist of P2Y14.

5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. Uridine 5'-monophosphate (Uridylic acid) is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside uridine. UMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase uracil.

Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM) and can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.

2',3'-Isopropylideneuridine is a nucleoside derivative that has shown antiviral activity in several studies, particularly against members of the Flaviviridae family (Flaviviruses), such as Hepatitis C virus (HCV).

Uridine 5'-monophosphate disodium salt (Disodium UMP) has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucleotides on growth of specific intestinal bacteria.

Uridine 5'-diphosphate sodium salt is a selective native agonist of the P2Y6 receptor (EC50: 300 nM; pEC50: 6.52) and a potent antagonist of P2Y14 (pEC50: 7.28).

Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.

Uridine diphosphate glucose (UDP-glucose) is a pyrimidine nucleotide sugar, serving as a precursor for oligosaccharides, polysaccharides, glycoproteins, and glycolipids containing glucose. It is a key intermediate in carbohydrate metabolism and participates in numerous enzymatic reactions, acting as a P2Y14 agonist.

Uridine triphosphate (UTP) is a purine nucleotide P2U receptor agonist with potential use in lung cancer treatment. By activating P2Y2 receptors, it enhances the proliferation of human cancerous ductal epithelial cells. Additionally, UTP induces fibrotic responses in cardiac fibroblasts through P2Y2 receptor activation and prolongs the action potential duration of guinea pig papillary muscles via the P2Y2 purinergic receptor.

Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled Uridine triphosphate sodium that can be used for isotope tracing.Uridine triphosphate (UTP) is a key in RNA synthesis molecule that serves as a substrate for RNA polymerase during transcription.

Uridine 5′-triphosphate tris salt (Uridine 5'-triphosphoric acid) is an agonist to the P2Y receptor and has been used to study concentrations of intracellular Ca2+, as well as a phosphate donor for in vitro kinase assays.

Uridine 5'-monophosphate (Standard) is the standard substance of Uridine 5'-monophosphate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. Uridine 5'-monophosphate (Uridylic acid) is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside uridine. UMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase uracil.

Uridine 5'-monophosphate disodium salt (Standard) is the standard substance of Uridine 5'-monophosphate disodium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Uridine 5'-monophosphate disodium salt (Disodium UMP) has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucleotides on growth of specific intestinal bacteria.

5-(Methoxycarbonyl)methyluridine, a uracil derivative, is an important modifying nucleotide in the anticodon loop of yeast tRNAs, allowing tRNAs to be correctly pre-structured and bind to codons on mRNAs, and the lack of the mcm5U modification (e.g., in elp3 mutant strains) leads to increased protein aggregation.

Uridine triphosphate (trisodium dihydrate) (UTP (trisodium dihydrate); Uridine 5'-triphosphate (trisodium dihydrate)) is utilized as a biomaterial or organic compound in life sciences research.

Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RNA synthesis.

Cytidine 5'-diphosphate trisodium salt (CDP) catalyzes the production of Cytidine triphosphate (CTP) for DNA and RNA synthesis by transferring a phosphoryl group from ATP to cytidine monophosphate (CMP) through the action of uridine monophosphate kinase (UMPK).