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Results for "

unwinding

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
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    1
    TargetMol | Natural_Products
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    9
    TargetMol | Recombinant_Protein
ATPγS tetralithium salt
ATP-gamma-S tetralithium salt
T2259293839-89-5In house
ATPγS tetralithium salt is a good substrate for RNA-stimulated nucleotide hydrolysis and RNA unwinding activity of eIF4A.
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Irinotecan hydrochloride trihydrate
Irinotecan HCl Trihydrate, CPT-11 HCl Trihydrate
T0486136572-09-3
Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.
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ML216
CID-49852229
T54131430213-30-1
ML216 (CID-49852229) is a small molecule inhibitor of BLM helicase with an IC50 of 1.8 μM, demonstrating 28-fold selectivity against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s > 50 μM).
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TargetMol | Citations Cited
TargetMol
GSK4418959
IDE275, IDE 275, GSK 4418959
T2040893064599-36-3
GSK4418959 (IDE275) is an orally active, non-covalent, reversible, and selective WRN helicase inhibitor. GSK4418959 inhibits ATPase and DNA unwinding functions in an ATP-competitive manner. GSK4418959 can be used to study MSI-H related research.
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10-14 weeks
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