trp5

Clemizole, an H1 histamine receptor antagonist, inhibits NS4B's RNA binding and hepatitis C virus (HCV) replication.

[D-Arg1,D-Trp5,7,9,Leu11]-Substance P is a potent inhibitor of small cell lung cancer (SCLC) cell growth. As a neuropeptide antagonist, [D-Arg1,D-Trp5,7,9,Leu11]-Substance P effectively blocks colony formation stimulated by multiple neuropeptides such as vasopressin and bradykinin. It inhibits Ca2+ mobilization and mitogen-activated protein kinase activation induced by vasopressin or bradykinin. [D-Arg1,D-Trp5,7,9,Leu11]-Substance P also suppresses the growth of H-69 xenografts in nude mice.

Clemizole (Standard) is the standard substance of Clemizole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.