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triphosphate

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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Acyclovir
Acycloguanosine, Aciclovir
T145459277-89-3
Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.
  • $39
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TargetMol | Citations Cited
Cytidine 5'-diphosphate trisodium salt
CDP
T4042634393-59-4
Cytidine 5'-diphosphate trisodium salt (CDP) catalyzes the production of Cytidine triphosphate (CTP) for DNA and RNA synthesis by transferring a phosphoryl group from ATP to cytidine monophosphate (CMP) through the action of uridine monophosphate kinase (UMPK).
  • $29
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IMT1
Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-, LDC195943(IMT1)
T88412304621-31-4
IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.
  • $74
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Guanosine-5'-triphosphate disodium salt
GTP disodium, 5'-GTP disodium salt
T1151156001-37-7
Guanosine-5'-triphosphate disodium salt (5'-GTP disodium salt) is an enhancer of myogenic cell differentiation and serves as an energy source for translation and other critical cellular processes.
  • $30
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Guanosine 5'-triphosphate trisodium salt
GTP Trisodium salt, 5'-GTP trisodium salt
T496936051-31-7
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates signal-transducing G proteins involved in cellular processes such as proliferation, differentiation, and activation of intracellular kinase cascades. It regulates proliferation and apoptosis through the hydrolysis by small GTPases Ras and Rho, and plays a role in vesicle docking, fusion, and formation via Rab. Additionally, GTP serves as an energy-rich precursor for the biosynthesis of DNA and RNA.
  • $42
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Cytidine-5'-triphosphate disodium
Cytidine 5'-triphosphate (disodium salt), CTP
T528836051-68-0
Cytidine 5'-triphosphate disodium salt is one of the endogenous metabolites and is a cation-permeable ligand-gated ion channel agonist.
  • $35
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Guanosine 5'-triphosphate trisodium salt hydrate
5'-GTP trisodium salt hydrate
T10178207300-85-4
5'-GTP trisodium salt hydrate, an activator of the signal-transducing G proteins, serves as a precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
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Galidesivir triphosphate
BCX4430-triphosphate, Immucillin-A triphosphate, BCX6870
T113521467740-78-8
Galidesivir triphosphate is a substrate for viral RNA-dependent RNA polymerase (RDRP), resulting in termination of viral RNA replication and thus serves as an antiviral. Galidesivir triphosphate inhibits HCV NS5B RNA polymerase activity and protects mice against Ebola. Galidesivir triphosphate (Immucillin-A triphosphate) is converted by the prodrug Galidesivir.
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6-8 weeks
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Deoxythymidine triphosphate
T166318423-43-3
Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.
  • $34
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N4-Acetylcytidine triphosphate sodium
ac4CTP sodium
T194622803886-33-9
N4-Acetylcytidine triphosphate sodium is an efficient substrate for T7 Polymerase-catalyzed in vitro transcription.
  • $486
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N4-Acetylcytidine triphosphate
ac4CTP
T194631428903-57-4
N4-Acetylcytidine triphosphate is an efficient substrate for T7 Polymerase-catalyzed in vitro transcription.
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NHC-triphosphate
T1947634973-27-8
NHC-triphosphate is a weak alternative substrate for the viral polymerase and changes the mobility of the product in polyacrylamide electrophoresis gels.
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6-8 weeks
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Guanosine triphosphate tritris
GTP tritris
T201035103192-46-7
Guanosine triphosphate tritris (GTP tritris) serves as a crucial enhancer in myocyte differentiation, playing an essential role in regulating miRNA-muscle regulatory factors. It promotes the release of exosomes rich in guanine and guanine-derived molecules, and is considered an activation precursor for RNA synthesis. In mitochondrial functionality, GTP is involved in the entry of proteins into the matrix, which is vital for various regulatory pathways. It initiates peptide synthesis by facilitating the binding of formylmethionine-tRNA to the ribosome, and aids in polypeptide chain elongation. Additionally, GTP acts as a carrier for phosphates and pyrophosphates, channeling chemical energy into specific biosynthetic pathways. It activates signal transduction G proteins, regulates cellular processes such as proliferation and differentiation, and its hydrolysis by small GTPases (including Ras and Rho) is indispensable for both proliferation and apoptosis. Furthermore, the small GTPase Rab assists in vesicle docking, fusion, and formation. Beyond signal transduction, GTP is also an energy-rich precursor in the biosynthesis of DNA and RNA enzymes.
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Uridine 5'-triphosphate tetrasodium
Uridine 5'-(tetrahydrogen triphosphate) tetrasodium salt
T20289914264-46-1
Uridine triphosphate (UTP) is a purine nucleotide P2U receptor agonist with potential use in lung cancer treatment. By activating P2Y2 receptors, it enhances the proliferation of human cancerous ductal epithelial cells. Additionally, UTP induces fibrotic responses in cardiac fibroblasts through P2Y2 receptor activation and prolongs the action potential duration of guinea pig papillary muscles via the P2Y2 purinergic receptor.
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10-14 weeks
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Kinetin triphosphate tetrasodium
KTP tetrasodium, 6-Fu-ATP tetrasodium, 6-FuATP tetrasodium
T203014
Kinetin triphosphate tetrasodium (KTP tetrasodium) is the tetrasodium salt form of Kinetin triphosphate, an ATP analog that enhances the activity of Parkinson's disease-associated mutant mitochondrial kinases PINK1(G309D) and PINK1(WT) and has therapeutic potential for neurodegenerative diseases.
  • $249
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Clofarabine-5'-triphosphate
Clofarabine-TP
T203136134646-41-6
Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.
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10-14 weeks
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Purine riboside-5'-O-triphosphate sodium
PTP tetrasodium
T20358635892-95-6
Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine (HY-103694) and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 µM.
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10-14 weeks
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(+)-Carbovir triphosphate
L-CBVTP, LCBVTP, L CBVTP
T23574144606-93-9
(+)-Carbovir triphosphate, an active metabolite of Abacavir, was utilized to study the molecular mechanism of inhibition and drug resistance in HIV-1 reverse transcriptase.
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3-6 months
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4'-Azidothymidine 5'-triphosphate
Adrt TP,Adrt-TP,AdrtTP
T29431140158-13-0
4'-Azidothymidine 5'-triphosphate exerts selectively action on both reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta.
  • $1,820
8-10 weeks
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Aminoquinol triphosphate
Aminochinol triphosphate
T299913653-53-0
Aminoquinol triphosphate may be useful in the treatment of acute necrotising cutaneous leishmaniasis.
  • $1,520
6-8 weeks
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3'-Deoxyuridine-5'-triphosphate
T3565769199-40-2
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II and strongly competes with UTP incorporation into RNA, with a Ki value of 2.0 μM[1].
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6-8 weeks
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3'-Deoxyuridine-5'-triphosphate trisodium
T35658
'3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II by competitively blocking UTP incorporation into RNA with a dissociation constant (Ki) of 2.0 μM[1].
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D-myo-Inositol-1,4,5-triphosphate tripotassium
Ins(1,4,5)-P3 tripotassium, Inositol 1,4,5-trisphosphate tripotassium
T35934141611-11-2
D-myo-Inositol-1,4,5-triphosphate tripotassium (Ins(1,4,5)-P3 tripotassium) is a second messenger in cellular signal transduction that triggers Ca2+ mobilization.
  • $113
35 days
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