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By Target- MAO
- NADPH(1)
- Nrf2(1)
- Others(1)
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Results for "
target/Reductase/2
" in TargetMol Product Catalog- Inhibitors & Agonists2
DHFR-IN-2
T60286331942-46-2
DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor of MtDHFR, with an IC50 of 7 μM. The enzyme dihydrofolate reductase from M. tuberculosis (MtDHFR) holds high unexploited potential as a drug target due to its importance for pathogen survival. DHFR-IN-2 can be used for tuberculosis (TB) research [1].
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Nrf2-ARE/hMAO-B/QR2 modulator 1
T603953035124-25-2
Nrf2-ARE hMAO-B QR2 modulator 1, a resveratrol derivative and multi-target-directed ligand (mtdl), activated the NRF2-ARE pathway (CD = 9.83 μM), selectively inhibited hMAO-B and QR2（quinone reductase-2，NQO2) (IC 50 = 8.05 and 0.57 μM), and was able to promote hippocampal neurogenesis and exert neuroprotective and antioxidant effects in an Alzheimer's disease model.
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