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(2)
By Tag- N-6xHis
- C-6xHis(1)
- C-Myc(1)
- N-10xHis(1)
- N-GST(1)
- Tag Free(1)
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By Tag By Expression System- E. coli(5)
- P. pastoris (Yeast)(1)
By Species- Human(6)
By SPR-compatible Buffer- Buffer exchange required(6)
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Results for "
smad1
" in TargetMol Product Catalog- Inhibitors & Agonists6
- Inhibitory Antibodies1
- Natural Products2
- Recombinant Protein6
CompareTransforming Growth Factor-β-Signaling Protein 1, Transforming Growth Factor-Beta-Signaling Protein 1, SMAD1, SMAD Family Member 1, SMAD 1, Mothers Against DPP Homolog 1, Mothers Against Decapentaplegic Homolog 1, Mad-Related Protein 1, MADR1, MADH1, MAD Homolog 1, JV4-1, hSMAD1, BSP-1, BSP1
TMPJ-01129
Expression system: E. coli
Length: 1-465, Full Length
Activity: Not Tested
Length: 1-465, Full Length
Activity: Not Tested
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CompareSMURF2, SMAD-specific E3 ubiquitin-protein ligase 2, SMAD ubiquitination regulatory factor 2, hSMURF2, HECT-type E3 ubiquitin transferase SMURF2, E3 ubiquitin-protein ligase SMURF2
TMPH-01269
Expression system: E. coli
Length: 1-748, Full Length
Activity: Not Tested
Length: 1-748, Full Length
Activity: Not Tested
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CompareGrowth differentiation factor 2, GDF-2, GDF2, Bone morphogenetic protein 9 (BMP-9), BMP9
TMPH-01414
Expression system: P. pastoris (Yeast)
Length: 300-429, Partial
Activity: Not Tested
Length: 300-429, Partial
Activity: Not Tested
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CompareSMAD6, SMAD family member 6 (SMAD 6;Smad6;hSMAD6), Mothers against DPP homolog 6, Mothers against decapentaplegic homolog 6, MADH6, MAD homolog 6
TMPH-01702
Expression system: E. coli
Length: 1-496, Full Length
Activity: Not Tested
Length: 1-496, Full Length
Activity: Not Tested
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CompareRadotermin, LPS-associated protein 4, Lipopolysaccharide-associated protein 4, LAP-4, Growth differentiation factor 5, GDF-5, CDMP-1, CDMP1, Cartilage-derived morphogenetic protein 1, Bone morphogenetic protein 14, BMP-14
TMPJ-00966
Expression system: E. coli
Length: 382-501, Full Length of Mature Protein
Activity: Not Tested
Length: 382-501, Full Length of Mature Protein
Activity: Not Tested
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CompareSMAD4, SMAD Family Member 4, SMAD 4, Mothers Against DPP Homolog 4, Mothers Against Decapentaplegic Homolog 4, MADH4, MAD Homolog 4, hSMAD4, DPC4, Deletion Target in Pancreatic Carcinoma 4
TMPJ-01108
SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD homology 2) domain. It is the component of the heterotrimeric SMAD2 SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. SMAD4 promotes binding of the SMAD2 SMAD4 FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. SMAD4 may act as a tumor suppressor. It positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. Mutations or deletions in SMAD4 have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.
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