sepiapterin reductase

QM385 is a potent inhibitor of sepiapterin reductase (SPR)(IC50 of 1.49 nM).

SPR inhibitor 3 is a class of small-molecule compounds used to inhibit the activity of sepiapterin reductase; it blocks the biosynthetic pathway of tetrahydrobiopterin (BH4), thereby affecting the production of nitric oxide synthase and monoamine neurotransmitters.

Homovanillic acid (Vanillacetic acid), a dopamine metabolite, is linked to aromatic L-amino acid decarboxylase deficiency, growth hormone deficiency, celiac disease, and sepiapterin reductase deficiency.

N-Acetyldopamine is a natural catecholamine exhibiting immunomodulatory and antioxidant effects, capable of attenuating LPS-induced TNF-α and superoxide production in THP-1 cells. It inhibits sepiapterin reductase activity.

(4-Hydroxy-3-methoxyphenyl) acetic-2,2-D2 Acid is a deuterated compound of  (4-Hydroxy-3-methoxyphenyl) acetic Acid (TMSM-3295). (4-Hydroxy-3-methoxyphenyl)acetic Acid has a CAS number of 306-08-1. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

Homovanillic Acid-13C-D3 the 13C and deuterated compound of Homovanillic Acid (T3S0507). Homovanillic Acid has a CAS number of 306-08-1. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

Homovanillic acid (Standard) is a reference standard for research and analysis in studies involving Homovanillic acid. Homovanillic acid (Vanillacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, growth hormone deficiency, celiac disease, and sepiapterin reductase deficiency.

(4-Hydroxy-3-Methoxyphenyl)Acetic-2,2-D2 Acid (Standard) is a reference standard of (4-Hydroxy-3-Methoxyphenyl)Acetic-2,2-D2 Acid intended for quantitative analysis, quality control, and related biochemical research applications. (4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid is a deuterated compound of (4-Hydroxy-3-methoxyphenyl)acetic Acid. (4-Hydroxy-3-methoxyphenyl)acetic Acid has a CAS number of 306-08-1. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.