scopolamine butylbromide

Scopolamine butylbromide ((-)-Scopolamine butylbromide) is a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM).

Scopolamine nitrate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

1. Scopolamine (Scopine (-)-tropate), a nonselective muscarinic receptor antagonist, induces distinct behaviors of attenuated motility and C-like hyperactivity. 2. Scopolamine can increase acetylcholinesterase activity by was significantly attenuated by RCM treatment. 3. Scopolamine can cause learning and memory impairments and galantamine can reverse the symptom. 4. Scopolamine produces rapid and significant symptom improvement in patients with depression.

Scopolamine hydrobromide ((-)-Scopolamine hydrobromide) is an alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in URINARY INCONTINENCE, in MOTION SICKNESS, as an antispasmodic, and as a mydriatic and cycloplegic.