quinazolinone — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8871	C/EBPα inducer 1	4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-	Others
	C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via upregulation of C/EBP.		Others
T24879	Thioxodihydroquinazolinone-19	Thioxodihydroquinazolinone19
	In platinum-resistant A2780cis human ovarian cancer cells, thioxodihydroquinazolinone-19 is an inducer of apoptotic cell death. It acts by exhibiting a strong inhibitory effect in ovarian CSC-LCs in combination with cisp...
T2103	Ispinesib	CK0238273,SB-715992	Apoptosis , Kinesin , KSP
	Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.		Apoptosis , Kinesin , KSP
T4993	Afloqualone	HQ-495	GABA Receptor
	Afloqualone (HQ-495) is a agonist of GABA Receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. It has sedative and muscle-relaxant effects, resulting from its agonist activity ...		GABA Receptor
T8785	HALOFUGINONE LACTATE		DNA/RNA Synthesis , TGF-beta/Smad
	HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner ...		DNA/RNA Synthesis , TGF-beta/Smad
T71574	Mci 176
	Mci 176 is a quinazolinone calcium antagonist.
T25431	Fluproquazone	Tormosyl,46 790,46-790
	Fluproquazone is a quinazolinone derivative with potent antipyretic, analgesic, and anti-inflammatory effects. However, it was withdrawn during development due to liver toxicity.
T83074	Anticancer agent 95
	Quinazolinone Compound 95, also known as Compound 24, exhibits anticancer properties [1].

Compounds

C/EBPα inducer 1

T8871

Synonym: 4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-

Target: Others

Thioxodihydroquinazolinone-19

T24879

Synonym: Thioxodihydroquinazolinone19

Target:

Ispinesib

T2103

Synonym: CK0238273,SB-715992

Target: Apoptosis, Kinesin, KSP

Afloqualone

T4993

Synonym: HQ-495

Target: GABA Receptor

HALOFUGINONE LACTATE

T8785

Synonym:

Target: DNA/RNA Synthesis, TGF-beta/Smad

Synonym: Tormosyl,46 790,46-790

Cat No.	Product Name	Synonyms	Targets
TMO2713	4(3H)-Quinazolinone	Quinazolin-4-ol,4-Hydroxyquinazoline,4-Quinazolinol,4-Quinazolone,4-Quinazolinone	Antibacterial , Platelet aggregation
	4(3H)-Quinazolinone (4-Hydroxyquinazoline) is a chemically synthesized masonry block, a biologically active nitrogen heterocyclic compound. It possesses various biological properties such as antibacterial, antifungal, an...		Antibacterial , Platelet aggregation
TN1012	Febrifugine		IL Receptor , Anti-infection , Parasite
	Febrifugine is an effective coccidiostat, possesses schizonticide props; it and its derivatives shows high degree of antimalarial activity but use limited by toxicity .		IL Receptor , Anti-infection , Parasite
TN1012L	Febrifugine dihydrochloride	ISF-2123,Propyldazine hydrochloride,Atensil,(+)-Febrifugine dihydrochloride,Pildralazine dihydrochloride	Parasite
	Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.		Parasite
T3524	Halofuginone hydrobromide	Tempostatin,RU-19110 (hydrobromide),Stenorol	Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...